Nervous System Bone Marrow-Derived APC in the Central T Lymphocytes Promote the Development of

[1]  M. Apuzzo,et al.  Cellular and Molecular Neurosurgery: Pathways from Concept to Reality-Part II: Vector Systems and Delivery Methodologies for Gene Therapy of the Central Nervous System. , 1997, Neurosurgery.

[2]  D. Dickson,et al.  The Pathogenesis of Senile Plaques , 1997, Journal of neuropathology and experimental neurology.

[3]  M. Apuzzo,et al.  Cellular and Molecular Neurosurgery: Pathways from Concept to Reality-Part I: Target Disorders and Concept Approaches to Gene Therapy of the Central Nervous System. , 1997, Neurosurgery.

[4]  D. Bourdette,et al.  Phenotype and function of hematopoietic‐derived cells in the CNS of SCID mouse‐lewis rat bone marrow chimeras , 1996, Journal of neuroscience research.

[5]  M. Schwartz,et al.  Transplantation of activated macrophages overcomes central nervous system regrowth failure , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[6]  J. Gehrmann.  Microglia: a sensor to threats in the nervous system? , 1996, Research in virology.

[7]  W. A. Rees,et al.  Biophysical studies of T-cell receptors and their ligands. , 1996, Current opinion in immunology.

[8]  J. Sedgwick.  Immune surveillance and autoantigen recognition in the central nervous system. , 1995, Australian and New Zealand journal of medicine.

[9]  Laurie H Glimcher,et al.  B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy , 1995, Cell.

[10]  G. Kreutzberg,et al.  Microglia: Intrinsic immuneffector cell of the brain , 1995, Brain Research Reviews.

[11]  L. Steinman,et al.  Escape from “horror autotoxicus”: Pathogenesis and treatment of autoimmune disease , 1995, Cell.

[12]  I. Cohen,et al.  Expression of major histocompatibility complex class II molecules in rat T cells , 1994, European journal of immunology.

[13]  L. Steinman,et al.  Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis. , 1994, The Journal of clinical investigation.

[14]  D. Hafler,et al.  Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. , 1994, Journal of immunology.

[15]  M. Hart,et al.  Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. , 1994, Immunology today.

[16]  D. Barten,et al.  Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis , 1994, Journal of Neuroimmunology.

[17]  H. Weiner,et al.  Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis , 1994, The Journal of experimental medicine.

[18]  K. Toyka,et al.  In situ detection of transforming growth factor-β mRNA in experimental rat glioma and reactive glial cells , 1994, Neuroscience Letters.

[19]  V. Kuchroo,et al.  Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. , 1993, Journal of immunology.

[20]  A. Weinberg,et al.  Lymphokine mRNA expression in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis is associated with a host recruited CD45R hi/CD4+ population during recovery , 1993, Journal of Neuroimmunology.

[21]  H. McFarland,et al.  Identification of a novel T cell epitope of human proteolipid protein (residues 40–60) recognized by proliferative and cytolytic CD4+ T cells from multiple sclerosis patients , 1993, Journal of Neuroimmunology.

[22]  A. Weinberg,et al.  Treatment of relapsing experimental autoimmune encephalomyelitis with T cell receptor peptides , 1993, Journal of neuroscience research.

[23]  D. Bourdette,et al.  Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells. , 1993, Journal of immunology.

[24]  Sudhir Gupta,et al.  Dual expression of CD45RA and CD45RO isoforms on myelin basic protein-specific CD4+ T-cell lines in multiple sclerosis , 1993, Journal of Clinical Immunology.

[25]  C. Janeway,et al.  Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma , 1993, The Journal of experimental medicine.

[26]  B. Haynes,et al.  In vivo models of human lymphopoiesis and autoimmunity in severe combined immune deficient mice , 1992, Journal of Clinical Immunology.

[27]  A. Vandenbark,et al.  TCR peptide therapy decreases the frequency of encephalitogenic T cells in the periphery and the central nervous system , 1992, Journal of Neuroimmunology.

[28]  Changhee Kim,et al.  A combination of adoptive transfer and antigenic challenge induces consistent murine experimental autoimmune encephalomyelitis in C57BL/6 mice and other reputed resistant strains , 1992, Journal of Neuroimmunology.

[29]  D. Bourdette,et al.  Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosis , 1992, Journal of Neuroimmunology.

[30]  H. Lassmann,et al.  Bone Marrow-derived Elements in the Central Nervous System: An Immunohistochemical and Ultrastructural Survey of Rat Chimeras , 1992, Journal of neuropathology and experimental neurology.

[31]  J. Dick,et al.  Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. , 1992, Science.

[32]  I. Goldschneider,et al.  Relative susceptibility of SJL/J and B10.S mice to experimental allergic encephalomyelitis is correlated with high and low responsiveness to myelin basic protein , 1991, Journal of Neuroimmunology.

[33]  W. Hickey,et al.  T‐lymphocyte entry into the central nervous system , 1991, Journal of neuroscience research.

[34]  R. Clark,et al.  An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis , 1990, The Journal of experimental medicine.

[35]  J. McCune,et al.  Long-term human hematopoiesis in the SCID-hu mouse , 1990, The Journal of experimental medicine.

[36]  H. Offner,et al.  Antibodies specific for VB8 receptor peptide suppress experimental autoimmune encephalomyelitis. , 1990, Journal of immunology.

[37]  L. Hood,et al.  Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies , 1990, The Journal of experimental medicine.

[38]  A. Vandenbark,et al.  Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis , 1989, Nature.

[39]  E. Heber-Katz,et al.  Protection from experimental allergic encephalomyelitis conferred by a monoclonal antibody directed against a shared idiotype on rat T cell receptors specific for myelin basic protein , 1988, The Journal of experimental medicine.

[40]  I. Weissman,et al.  The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. , 1988, Science.

[41]  W. Hickey,et al.  Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. , 1988, Science.

[42]  D. Hinrichs,et al.  Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element , 1987, The Journal of experimental medicine.

[43]  H. Lassmann,et al.  Cellular immune reactivity within the CNS , 1986, Trends in Neurosciences.

[44]  P. M. Chisholm,et al.  Co-expression of CD4 and CD8 molecules and de novo expression of MHC class II antigens on activated rat T cells. , 1986, Immunology.

[45]  R. Custer,et al.  A severe combined immunodeficiency mutation in the mouse , 1983, Nature.

[46]  R. Zinkernagel,et al.  Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system , 1974, Nature.

[47]  E. Shevach,et al.  FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES , 1973, The Journal of experimental medicine.

[48]  H. McFarland,et al.  T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes. , 1993, Autoimmunity.

[49]  K. Black,et al.  Response of microglial cells to experimental rat glioma , 1992, Glia.