Association of dopamine D2/3 receptor binding potential measured using PET and [11C]-(+)-PHNO with post-mortem DRD2/3 gene expression in the human brain

[1]  Rupert Lanzenberger,et al.  Topologically Guided Prioritization of Candidate Gene Transcripts Coexpressed with the 5-HT1A Receptor by Combining In Vivo PET and Allen Human Brain Atlas Data , 2020, Cerebral cortex.

[2]  G. Dorffner,et al.  On the relationship of first-episode psychosis to the amphetamine-sensitized state: a dopamine D2/3 receptor agonist radioligand study , 2020, Translational Psychiatry.

[3]  David Liljequist,et al.  Intraclass correlation – A discussion and demonstration of basic features , 2019, PloS one.

[4]  Ben D. Fulcher,et al.  A practical guide to linking brain-wide gene expression and neuroimaging data , 2018, NeuroImage.

[5]  Louis Richer,et al.  Cell-Specific Gene-Expression Profiles and Cortical Thickness in the Human Brain , 2018, Cerebral cortex.

[6]  Siegfried Kasper,et al.  Spatial analysis and high resolution mapping of the human whole-brain transcriptome for integrative analysis in neuroimaging , 2018, NeuroImage.

[7]  A. Bernacchia,et al.  Hierarchy of transcriptomic specialization across human cortex captured by structural neuroimaging topography , 2018, Nature Neuroscience.

[8]  Jan Mauer,et al.  FTO, m6Am, and the hypothesis of reversible epitranscriptomic mRNA modifications , 2018, FEBS letters.

[9]  John D. Murray,et al.  Hierarchy of transcriptomic specialization across human cortex captured by myelin map topography , 2017, bioRxiv.

[10]  Wolfgang M Pauli,et al.  Descriptor : A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei , 2018 .

[11]  Vince D. Calhoun,et al.  Regional and source-based patterns of [11C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D2 and D3 receptor availability in cocaine-use disorder , 2017, NeuroImage.

[12]  A. Komorowski,et al.  Association of Protein Distribution and Gene Expression Revealed by PET and Post-Mortem Quantification in the Serotonergic System of the Human Brain , 2016, Cerebral cortex.

[13]  Gal Chechik,et al.  On Expression Patterns and Developmental Origin of Human Brain Regions , 2016, PLoS Comput. Biol..

[14]  Chen Chu,et al.  Analysis of Gene Expression Profiles in the Human Brain Stem, Cerebellum and Cerebral Cortex , 2016, PloS one.

[15]  Stanley J. Watson,et al.  Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model , 2016, Proceedings of the National Academy of Sciences.

[16]  Richard E. Carson,et al.  Age-related changes in binding of the D2/3 receptor radioligand [11C](+)PHNO in healthy volunteers , 2016, NeuroImage.

[17]  Robert B. Innis,et al.  Measuring specific receptor binding of a PET radioligand in human brain without pharmacological blockade: The genomic plot , 2016, NeuroImage.

[18]  P. Expert,et al.  MENGA: A New Comprehensive Tool for the Integration of Neuroimaging Data and the Allen Human Brain Transcriptome Atlas , 2016, PloS one.

[19]  Robert B. Innis,et al.  A new method for measuring specific receptor binding of a PET radioligand in human brain without pharmacological blockade , 2016 .

[20]  Shinichiro Nakajima,et al.  Imaging the D3 dopamine receptor across behavioral and drug addictions: Positron emission tomography studies with [11C]-(+)-PHNO , 2015, European Neuropsychopharmacology.

[21]  M. Rietschel,et al.  Correlated gene expression supports synchronous activity in brain networks , 2015, Science.

[22]  Sylvain Houle,et al.  Lack of Age-Dependent Decrease in Dopamine D3 Receptor Availability: A [11C]-(+)-PHNO and [11C]-Raclopride Positron Emission Tomography Study , 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[23]  Shinichiro Nakajima,et al.  Imaging the D 3 dopamine receptor across behavioral and drug addictions: Positron emission tomography studies , 2015 .

[24]  Gaia Rizzo,et al.  Imaging of monoamine oxidase-A in the human brain with [11C]befloxatone: quantification strategies and correlation with mRNA transcription maps , 2014, Nuclear medicine communications.

[25]  A. Raj,et al.  Spatial patterns of genome‐wide expression profiles reflect anatomic and fiber connectivity architecture of healthy human brain , 2014, Human brain mapping.

[26]  Sylvain Houle,et al.  Stress-Induced Dopamine Response in Subjects at Clinical High Risk for Schizophrenia with and without Concurrent Cannabis Use , 2014, Neuropsychopharmacology.

[27]  Sylvain Houle,et al.  Heightened D3 Dopamine Receptor Levels in Cocaine Dependence and Contributions to the Addiction Behavioral Phenotype: A Positron Emission Tomography Study with [11C]-(+)-PHNO , 2014, Neuropsychopharmacology.

[28]  Wolfgang Wadsak,et al.  Reliable set-up for in-loop 11C-carboxylations using Grignard reactions for the preparation of [carbonyl-11C]WAY-100635 and [11C]-(+)-PHNO☆ , 2013, Applied Radiation and Isotopes.

[29]  Sylvain Houle,et al.  Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive task. , 2013, Journal of psychiatry & neuroscience : JPN.

[30]  Allan R. Jones,et al.  The Allen Human Brain Atlas Comprehensive gene expression mapping of the human brain , 2012, Trends in Neurosciences.

[31]  David C. Glahn Faculty Opinions recommendation of An anatomically comprehensive atlas of the adult human brain transcriptome. , 2012 .

[32]  Allan R. Jones,et al.  An anatomically comprehensive atlas of the adult human brain transcriptome , 2012, Nature.

[33]  Richard E Carson,et al.  Affinity and selectivity of [11C]‐(+)‐PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo , 2012, Synapse.

[34]  Jens C. Pruessner,et al.  Increased Stress-Induced Dopamine Release in Psychosis , 2012, Biological Psychiatry.

[35]  Sylvain Houle,et al.  Higher Binding of the Dopamine D3 Receptor-Preferring Ligand [11C]-(+)-Propyl-Hexahydro-Naphtho-Oxazin in Methamphetamine Polydrug Users: A Positron Emission Tomography Study , 2012, The Journal of Neuroscience.

[36]  Sylvain Houle,et al.  Effects of antipsychotics on D3 receptors: A clinical PET study in first episode antipsychotic naive patients with schizophrenia using [11C]-(+)-PHNO , 2011, Schizophrenia Research.

[37]  R. Gainetdinov,et al.  The Physiology, Signaling, and Pharmacology of Dopamine Receptors , 2011, Pharmacological Reviews.

[38]  Mark Jenkinson,et al.  Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy , 2011, NeuroImage.

[39]  John D. Beaver,et al.  Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C]PHNO, and a Selective D3 Receptor Antagonist , 2010, Biological Psychiatry.

[40]  Sylvain Houle,et al.  Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925. , 2010, The international journal of neuropsychopharmacology.

[41]  Luis Serrano,et al.  Correlation of mRNA and protein in complex biological samples , 2009, FEBS letters.

[42]  Mark Slifstein,et al.  In vivo quantification of regional dopamine‐D3 receptor binding potential of (+)‐PHNO: Studies in non‐human primates and transgenic mice , 2009, Synapse.

[43]  Ariel Graff-Guerrero,et al.  The Dopamine D2 Receptors in High-Affinity State and D3 Receptors in Schizophrenia: A Clinical [11C]-(+)-PHNO PET Study , 2009, Neuropsychopharmacology.

[44]  Alan A. Wilson,et al.  First Human Evidence of d-Amphetamine Induced Displacement of a D2/3 Agonist Radioligand: A [11C]-(+)-PHNO Positron Emission Tomography Study , 2008, Neuropsychopharmacology.

[45]  John R. Sims,et al.  Dopamine receptor mRNA and protein expression in the mouse corpus striatum and cerebral cortex during pre- and postnatal development , 2007, Brain Research.

[46]  Shitij Kapur,et al.  Increased dopamine D2High receptors in amphetamine‐sensitized rats, measured by the agonist [3H](+)PHNO , 2007, Synapse.

[47]  Sylvain Houle,et al.  Positron Emission Tomography Quantification of [11C]-(+)-PHNO Binding in the Human Brain , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[48]  S. Kapur,et al.  Separate brain regions code for salience vs. valence during reward prediction in humans , 2007, Human brain mapping.

[49]  Shitij Kapur,et al.  Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO. , 2007, Synapse.

[50]  Sylvain Houle,et al.  Binding characteristics and sensitivity to endogenous dopamine of [11C]‐(+)‐PHNO, a new agonist radiotracer for imaging the high‐affinity state of D2 receptors in vivo using positron emission tomography , 2006, Journal of neurochemistry.

[51]  Sylvain Houle,et al.  High-Affinity States of Human Brain Dopamine D2/3 Receptors Imaged by the Agonist [11C]-(+)-PHNO , 2006, Biological Psychiatry.

[52]  Sylvain Houle,et al.  Radiosynthesis and evaluation of [11C]-(+)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol as a potential radiotracer for in vivo imaging of the dopamine D2 high-affinity state with positron emission tomography. , 2005, Journal of medicinal chemistry.

[53]  Richard E Carson,et al.  Noise Reduction in the Simplified Reference Tissue Model for Neuroreceptor Functional Imaging , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[54]  Nora D. Volkow,et al.  Imaging Monoamine Oxidase in the Human Brain , 1999 .

[55]  B. Levant,et al.  Differential distribution of D3 dopamine receptors in the brains of several mammalian species , 1998, Brain Research.

[56]  Christer Halldin,et al.  Autoradiographic localization of extrastriatal D2‐dopamine receptors in the human brain using [125I]epidepride , 1996, Synapse.

[57]  P Seeman,et al.  Dopamine D2 receptors mapped in rat brain with [3H](+)PHNO , 1994, Synapse.

[58]  R D Larsen,et al.  Dopamine receptors labelled by PHNO , 1993, Synapse.

[59]  M. Martres,et al.  Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor. , 1992, European journal of pharmacology.

[60]  J. Palacios,et al.  Dopamine receptors in human brain: Autoradiographic distribution of D2 sites , 1989, Neuroscience.

[61]  P. Seeman,et al.  The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form. , 1985, Endocrinology.