Transmission and Reflection Diffraction Tomography in Breast Imaging

Commercial medical ultrasound scanners produce images of human tissue by interpreting the information carried by echoes reflected from structures contained inside it. In this paper, a new generation of toroidal ultrasound arrays is used to measure both the signals reflected and transmitted through the tissue. It is shown that transmission measurements encode complete information about the gross structure of the tissue and lead to images that are superior to those obtained form reflection measurements alone. Experimental results are provided for a gel phantom and a human breast in vivo.

[1]  Lianjie Huang,et al.  From beamforming to diffraction tomography , 2008 .

[2]  R. Waag,et al.  An Eigenfunction Method for Reconstruction of Large-Scale and High-Contrast Objects , 2007, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[3]  Russell J Fedewa,et al.  A ring transducer system for medical ultrasound research. , 2006, IEEE transactions on ultrasonics, ferroelectrics, and frequency control.

[4]  N. Duric,et al.  Detection of breast cancer with ultrasound tomography: first results with the Computed Ultrasound Risk Evaluation (CURE) prototype. , 2007, Medical physics.

[5]  Lin,et al.  Quantitative imaging using a time-domain eigenfunction method , 2000, The Journal of the Acoustical Society of America.

[6]  T. V. Oughton,et al.  Breast imaging in coronal planes with simultaneous pulse echo and transmission ultrasound. , 1981, Science.

[7]  J. Greenleaf,et al.  ALGEBRAIC RECONSTRUCTION OF SPATIAL DISTRIBUTIONS OF ACOUSTIC VELOCITIES IN TISSUE FROM THEIR TIME-OF-FLIGHT PROFILES. , 1975 .

[8]  E. H. Linfoot.  Principles of Optics , 1961 .

[9]  M. Worthington,et al.  Resolution limits in ray tomography due to wave behavior: Numerical experiments , 1993 .

[10]  T. M. Kolb,et al.  Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. , 2002, Radiology.

[11]  D. A. Palmer,et al.  High‐speed data acquisition in a diffraction tomography system employing large‐scale toroidal arrays , 1997 .

[12]  S. L. Lee,et al.  Algebraic Reconstruction of Spatial Distributions of Acoustic Absorption within Tissue from Their Two-Dimensional Acoustic Projections , 1974 .

[13]  F. L. Thurstone,et al.  Acoustic Speckle: Theory and Experimental Analysis , 1979 .

[14]  F Simonetti,et al.  Imaging beyond the Born approximation: an experimental investigation with an ultrasonic ring array. , 2007, Physical review. E, Statistical, nonlinear, and soft matter physics.

[15]  R.C. Waag,et al.  A Ring Transducer System for Medical , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.