Age‐associated alterations in corpus callosum white matter integrity in bipolar disorder assessed using probabilistic tractography

Atypical age‐associated changes in white matter integrity may play a role in the neurobiology of bipolar disorder, but no studies have examined the major white matter tracts using nonlinear statistical modeling across a wide age range in this disorder. The goal of this study was to identify possible deviations in the typical pattern of age‐associated changes in white matter integrity in patients with bipolar disorder across the age range of 9–62 years.

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