Rapid, Wnt-Induced Changes in GSK3β Associations that Regulate β-Catenin Stabilization Are Mediated by Gα Proteins

[1]  V. Katanaev,et al.  Trimeric G Protein-Dependent Frizzled Signaling in Drosophila , 2005, Cell.

[2]  G. Struhl,et al.  Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Wange Lu,et al.  Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth , 2004, Cell.

[4]  Xi He Wnt Signaling Went derailed Again a New Track via the LIN-18 Receptor? , 2004, Cell.

[5]  R. J. Hill,et al.  C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling , 2004, Cell.

[6]  Keith Brennan,et al.  Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize β-catenin independently of Frizzled proteins , 2004, Oncogene.

[7]  Xi He,et al.  LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way , 2004, Development.

[8]  E. Wieschaus,et al.  A Nuclear Function for Armadillo/β-Catenin , 2004, PLoS biology.

[9]  H. Varmus,et al.  Requirement for a Nuclear Function of β-Catenin in Wnt Signaling , 2003, Molecular and Cellular Biology.

[10]  Reinhart Heinrich,et al.  The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway , 2003, PLoS biology.

[11]  Nobuyuki Onishi,et al.  The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[12]  Hsien-yu Wang,et al.  Wnt Signaling, Ca2+, and Cyclic GMP: Visualizing Frizzled Functions , 2003, Science.

[13]  I. Weissman,et al.  Wnt proteins are lipid-modified and can act as stem cell growth factors , 2003, Nature.

[14]  H. Varmus,et al.  Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors , 2003, BMC Cell Biology.

[15]  Richard W. Carthew,et al.  Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway , 2003, Nature.

[16]  John B. Thomas,et al.  Wnt-mediated axon guidance via the Drosophila Derailed receptor , 2003, Nature.

[17]  G. Milligan Principles: extending the utility of [35S]GTP gamma S binding assays. , 2003, Trends in pharmacological sciences.

[18]  Kenneth R Chien,et al.  Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure , 2002, Development.

[19]  J. J. Carrillo,et al.  Measurement of Agonist-Dependent and -Independent Signal Initiation of α1b-Adrenoceptor Mutants by Direct Analysis of Guanine Nucleotide Exchange on the G Protein Gα11 , 2002, Journal of Pharmacology and Experimental Therapeutics.

[20]  N. Perrimon,et al.  The Promise and Perils of Wnt Signaling Through β-Catenin , 2002, Science.

[21]  Matthias Mann,et al.  Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. , 2002, Genes & development.

[22]  Xi He,et al.  Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism , 2002, Cell.

[23]  R. Moon,et al.  G Protein Signaling from Activated Rat Frizzled-1 to the β-Catenin-Lef-Tcf Pathway , 2001, Science.

[24]  J Mao,et al.  Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. , 2001, Molecular cell.

[25]  William C. Skarnes,et al.  An LDL-receptor-related protein mediates Wnt signalling in mice , 2000, Nature.

[26]  Yoichi Kato,et al.  LDL-receptor-related proteins in Wnt signal transduction , 2000, Nature.

[27]  Andrew Tomlinson,et al.  arrow encodes an LDL-receptor-related protein essential for Wingless signalling , 2000, Nature.

[28]  A. Antipova,et al.  Interaction of Dishevelled and XenopusAxin-Related Protein Is Required for Wnt Signal Transduction , 2000, Molecular and Cellular Biology.

[29]  M. Kirschner,et al.  Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. , 2000, Molecular cell.

[30]  R. Moon,et al.  Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Nusse,et al.  Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. , 1999, Genes & development.

[32]  T. Dale,et al.  Interaction of Axin and Dvl‐2 proteins regulates Dvl‐2‐stimulated TCF‐dependent transcription , 1999, The EMBO journal.

[33]  M. Kitagawa,et al.  An F‐box protein, FWD1, mediates ubiquitin‐dependent proteolysis of β‐catenin , 1999, The EMBO journal.

[34]  Hideki Yamamoto,et al.  Phosphorylation of Axin, a Wnt Signal Negative Regulator, by Glycogen Synthase Kinase-3β Regulates Its Stability* , 1999, The Journal of Biological Chemistry.

[35]  Fumiaki Ito,et al.  Cytoskeletal reorganization by soluble Wnt‐3a protein signalling , 1998, Genes to cells : devoted to molecular & cellular mechanisms.

[36]  S. Aaronson,et al.  Characterization of Wnt-1 and Wnt-2 induced growth alterations and signaling pathways in NIH3T3 fibroblasts , 1998, Oncogene.

[37]  Paul Polakis,et al.  Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β , 1998, Current Biology.

[38]  M. Humphries,et al.  The structure of cell-adhesion molecules. , 1998, Trends in cell biology.

[39]  R. Moon,et al.  Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling , 1997, Nature.

[40]  R. Moon,et al.  Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A. , 1997, Developmental biology.

[41]  R. Moon,et al.  A frizzled homolog functions in a vertebrate Wnt signaling pathway , 1996, Current Biology.

[42]  Jeremy Nathans,et al.  A new member of the frizzled family from Drosophila functions as a Wingless receptor , 1996, Nature.

[43]  Norbert Perrimon,et al.  dishevelled and armadillo act in the Wingless signalling pathway in Drosophila , 1994, Nature.

[44]  Hsien-yu Wang,et al.  Antisense oligodeoxynucleotides to Gs protein α-subunit sequence accelerate differentiation of fibroblasts to adipocytes , 1992, Nature.

[45]  H. Lodish,et al.  Insulin and nonhydrolyzable GTP analogs induce translocation of GLUT 4 to the plasma membrane in alpha-toxin-permeabilized rat adipose cells. , 1991, The Journal of biological chemistry.

[46]  H. Varmus,et al.  Requirement for a nuclear function of beta-catenin in Wnt signaling. , 2003, Molecular and cellular biology.

[47]  R. Moon,et al.  Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. , 2003, Nature.

[48]  N. Perrimon,et al.  The promise and perils of Wnt signaling through beta-catenin. , 2002, Science.

[49]  G. Milligan,et al.  Measurement of Agonist-Dependent and -Independent Signal Initiation of (cid:1) 1b -Adrenoceptor Mutants by Direct Analysis of Guanine Nucleotide Exchange on the G Protein G (cid:1) 11 , 2002 .

[50]  Xi He,et al.  Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. , 2002, Cell.

[51]  P. Polakis,et al.  Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. , 1998, Current biology : CB.