Cholangiocyte proliferation and liver fibrosis
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[1] A. Benedetti,et al. Control of Cholangiocyte Adaptive Responses by Visceral Hormones and Neuropeptides , 2009, Clinical reviews in allergy & immunology.
[2] P. Gartside,et al. Bile duct changes in alcoholic liver disease , 2008 .
[3] N. LaRusso,et al. Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[4] J. Medina-Pestana,et al. Serum levels of YKL‐40 and hyaluronic acid as noninvasive markers of liver fibrosis in haemodialysis patients with chronic hepatitis C virus infection , 2008, Journal of viral hepatitis.
[5] Hong Wang,et al. Interaction of CD44 and hyaluronic acid enhances biliary epithelial proliferation in cholestatic livers. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[6] D. Schuppan,et al. Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression. , 2008, Gastroenterology.
[7] A. Franchitto,et al. Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. , 2008, American journal of physiology. Cell physiology.
[8] A. Torrice,et al. Insulin-like growth factor-1 isoforms in rat hepatocytes and cholangiocytes and their involvement in protection against cholestatic injury , 2008, Laboratory Investigation.
[9] R. Mancinelli,et al. Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[10] M. Ebrahimkhani,et al. Wound healing and local neuroendocrine regulation in the injured liver , 2008, Expert Reviews in Molecular Medicine.
[11] H. Friess,et al. Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies. , 2008, Journal of hepatology.
[12] F. Marra,et al. Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario. , 2008, Molecular aspects of medicine.
[13] M. Pekalski,et al. Epithelial–mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease , 2008, Laboratory Investigation.
[14] Ji Won Kim,et al. Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis. , 2008, Human pathology.
[15] G. Rasi,et al. Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma. , 2007, World journal of gastroenterology.
[16] S. Glaser,et al. Knockout of α-calcitonin gene-related peptide reduces cholangiocyte proliferation in bile duct ligated mice , 2007, Laboratory Investigation.
[17] S. Glaser,et al. Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis. , 2007, Gastroenterology.
[18] H. Tilg,et al. Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. , 2007, Gastroenterology.
[19] N. Voelkel,et al. VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice. , 2007, American journal of physiology. Cell physiology.
[20] Merlin C. Thomas,et al. The Role of Tubular Epithelial-Mesenchymal Transition in Progressive Kidney Disease , 2007, Cells Tissues Organs.
[21] A. Franchitto,et al. H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway , 2007, Laboratory Investigation.
[22] S. Glaser,et al. Cytoprotective effects of taurocholic acid feeding on the biliary tree after adrenergic denervation of the liver , 2007, Liver international : official journal of the International Association for the Study of the Liver.
[23] David C. Jones,et al. Biliary epithelial‐mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis , 2007, Hepatology.
[24] J. Sicklick,et al. Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation , 2007, Laboratory Investigation.
[25] N. LaRusso,et al. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. , 2007, Gastroenterology.
[26] S. Glaser,et al. Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver. , 2007, Gastroenterology.
[27] M. Harbeck,et al. Cell physiology of cAMP sensor Epac , 2006, The Journal of physiology.
[28] H. Yoshiji,et al. Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development. , 2006, Hepatology research : the official journal of the Japan Society of Hepatology.
[29] T. Springer,et al. Integrin structures and conformational signaling. , 2006, Current opinion in cell biology.
[30] J. Sicklick,et al. Evidence for epithelial-mesenchymal transitions in adult liver cells. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[31] L. Bryan-Lluka,et al. A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. , 2006, The American journal of pathology.
[32] A. Franchitto,et al. Administration of r-VEGF-A prevents hepatic artery ligation-induced bile duct damage in bile duct ligated rats. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[33] S. Glaser,et al. Heterogeneity of the intrahepatic biliary epithelium. , 2006, World journal of gastroenterology.
[34] G. Svegliati-Baroni,et al. Estrogens maintain bile duct mass and reduce apoptosis after biliodigestive anastomosis in bile duct ligated rats. , 2006, Journal of hepatology.
[35] T. Roskams,et al. Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases , 2006, Hepatology.
[36] Yan-chun Zhou,et al. Modulation of expression and function of Toll-like receptor 3 in A549 and H292 cells by histamine. , 2006, Molecular immunology.
[37] G. Stoica,et al. Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. , 2006, Gastroenterology.
[38] S. Glaser,et al. Adrenergic receptor agonists prevent bile duct injury induced by adrenergic denervation by increased cAMP levels and activation of Akt. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[39] Tao Li,et al. Effects of 5-hydroxytamine and its antagonists on hepatic stellate cells. , 2006, Hepatobiliary & pancreatic diseases international : HBPD INT.
[40] C. Ganellin,et al. Histamine and its receptors , 2006, British journal of pharmacology.
[41] B. Rehermann,et al. The liver as an immunological organ , 2004 .
[42] A. Franchitto,et al. The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis. , 2005, Journal of hepatology.
[43] A. Vercelli,et al. Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis. , 2005, World journal of gastroenterology.
[44] W. Grizzle,et al. Cholangiocyte endothelin 1 and transforming growth factor beta1 production in rat experimental hepatopulmonary syndrome. , 2005, Gastroenterology.
[45] S. Glaser,et al. Secretin activation of the apical Na+‐dependent bile acid transporter is associated with cholehepatic shunting in rats , 2005, Hepatology.
[46] M. Richardson,et al. Fibrosis correlates with a ductular reaction in hepatitis C: Roles of impaired replication, progenitor cells and steatosis , 2005, Hepatology.
[47] T. Roskams,et al. Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin. , 2005, Gastroenterology.
[48] A. Franchitto,et al. Estrogen receptors in cholangiocytes and the progression of primary biliary cirrhosis. , 2004, Journal of hepatology.
[49] N. LaRusso,et al. The cholangiopathies: disorders of biliary epithelia. , 2004, Gastroenterology.
[50] S. Glaser,et al. cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway. , 2004, Journal of hepatology.
[51] S. Glaser,et al. Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis. , 2004, Gastroenterology.
[52] E. Brambilla,et al. Expression of vascular endothelial growth factor (VEGF) and its receptors (VEGF-R1 [Flt-1] and VEGF-R2 [KDR/Flk-1]) in tumorlets and in neuroendocrine cell hyperplasia of the lung. , 2004, Human pathology.
[53] G. Tiegs,et al. Innervation of immune cells: evidence for neuroimmunomodulation in the liver. , 2004, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.
[54] N. LaRusso,et al. The Pathophysiology of Biliary Epithelia , 2004 .
[55] E. Gaudio,et al. Tamoxifen in treatment of primary biliary cirrhosis , 2004, Hepatology.
[56] G. Tiegs,et al. Neurokinin-1 Receptor Antagonists Protect Mice from CD95- and Tumor Necrosis Factor-α-Mediated Apoptotic Liver Damage , 2004, Journal of Pharmacology and Experimental Therapeutics.
[57] N. Sinelli,et al. Hepatic fibrogenesis requires sympathetic neurotransmitters , 2004, Gut.
[58] Simi Ali,et al. Chronic renal allograft dysfunction: the role of T cell-mediated tubular epithelial to mesenchymal cell transition. , 2004, Journal of the American Society of Nephrology : JASN.
[59] T. Patel,et al. Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[60] S. Glaser,et al. Gastrin reverses established cholangiocyte proliferation and enhanced secretin‐stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+‐dependent PKC isoforms , 2003, Liver international : official journal of the International Association for the Study of the Liver.
[61] A. Vollmar,et al. Neurokinin-1 Receptor Antagonists CP-96,345 and L-733,060 Protect Mice from Cytokine-Mediated Liver Injury , 2003, Journal of Pharmacology and Experimental Therapeutics.
[62] R. Hultcrantz,et al. The Myofibroblastic Conversion of Peribiliary Fibrogenic Cells Distinct from Hepatic Stellate Cells Is Stimulated by Platelet-Derived Growth Factor During Liver Fibrogenesis , 2003, Laboratory Investigation.
[63] D. Drucker. Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. , 2003, Molecular endocrinology.
[64] L. Boros,et al. Cultured pancreatic ductal cells undergo cell cycle re-distribution and beta-cell-like differentiation in response to glucagon-like peptide-1. , 2002, Journal of molecular endocrinology.
[65] A. Franchitto,et al. Intracellular pathways mediating estrogen‐induced cholangiocyte proliferation in the rat , 2002, Hepatology.
[66] S. Morini,et al. Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes. , 2002, Gastroenterology.
[67] S. Sumitran-Holgersson,et al. High frequency of autoantibodies in patients with primary sclerosing cholangitis that bind biliary epithelial cells and induce expression of CD44 and production of interleukin 6 , 2002, Gut.
[68] S. Glaser,et al. Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha , 2002, Hepatology.
[69] M. Tammi,et al. Hyaluronan and Homeostasis: A Balancing Act* , 2002, The Journal of Biological Chemistry.
[70] M. Válková. Hepatic fibrogenesis. , 2002, Bratislavske lekarske listy.
[71] D. Wendum,et al. Hepatic Stellate Cell Proliferation is an Early Platelet-Derived Growth Factor-Mediated Cellular Event in Rat Cholestatic Liver Injury , 2001, Laboratory Investigation.
[72] S. Glaser,et al. Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes , 2001, Hepatology.
[73] H. Mitomi,et al. Significant correlations of E-cadherin, catenin, and CD44 variant form expression with carcinoma cell differentiation and prognosis of extrahepatic bile duct carcinomas. , 2001, American journal of clinical pathology.
[74] S. Glaser,et al. Regulation of cholangiocyte bicarbonate secretion. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[75] S. Glaser,et al. Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis. , 2001, American journal of physiology. Gastrointestinal and liver physiology.
[76] M. Beckmann,et al. Hormone Replacement Therapy after Treatment of Breast Cancer: Effects on Postmenopausal Symptoms, Bone Mineral Density and Recurrence Rates , 2001, Oncology.
[77] D. Schuppan,et al. Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis. , 2001, The American journal of pathology.
[78] A. Franchitto,et al. Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats. , 2000, Gastroenterology.
[79] F. Pierau,et al. Inhibitory neurogenic modulation of histamine-induced cutaneous plasma extravasation in the pigeon , 2000, Regulatory Peptides.
[80] N F LaRusso,et al. Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[81] S. Glaser,et al. Gastrin inhibits cholangiocyte growth in bile duct–ligated rats by interaction with cholecystokinin‐B/gastrin receptors via D ‐myo‐inositol 1,4,5‐triphosphate–, Ca2+‐, and protein kinase C α–dependent mechanisms , 2000 .
[82] D. Schuppan,et al. An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. , 2000, Gastroenterology.
[83] J. Bajorath. Molecular organization, structural features, and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions , 2000, Proteins.
[84] H. Herbst,et al. Expression of platelet-derived growth factor in newly formed cholangiocytes during experimental biliary fibrosis in rats. , 1999, Journal of hepatology.
[85] S. Glaser,et al. Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats. , 1999, Gastroenterology.
[86] Jones Ea,et al. The pathogenesis and treatment of pruritus and fatigue in patients with PBC. , 1999 .
[87] S. Glaser,et al. Acute carbon tetrachloride feeding induces damage of large but not small cholangiocytes from BDL rat liver. , 1999, American journal of physiology. Gastrointestinal and liver physiology.
[88] I. Shimizu,et al. Suppressive effects of estradiol on dimethylnitrosamine‐induced fibrosis of the liver in rats , 1999, Hepatology.
[89] J. Olynyk,et al. Oval cell numbers in human chronic liver diseases are directly related to disease severity. , 1999, The American journal of pathology.
[90] S. Glaser,et al. Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver , 1999, Hepatology.
[91] S. Glaser,et al. Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion. , 1999, Gastroenterology.
[92] N. Bergasa,et al. The pathogenesis and treatment of pruritus and fatigue in patients with PBC. , 1999, European journal of gastroenterology & hepatology.
[93] V. Desmet,et al. Ductular reaction and its diagnostic significance. , 1998, Seminars in diagnostic pathology.
[94] N. LaRusso,et al. Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation. , 1998, American journal of physiology. Gastrointestinal and liver physiology.
[95] L. Miller,et al. Secretin and vasoactive intestinal peptide receptors: members of a unique family of G protein-coupled receptors. , 1998, Gastroenterology.
[96] N. LaRusso,et al. The pathobiology of biliary epithelia , 2002, Hepatology.
[97] P. Dawson,et al. Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter. , 1997, The Journal of clinical investigation.
[98] S. Glaser,et al. Functional expression of the apical Na+-dependent bile acid transporter in large but not small rat cholangiocytes. , 1997, Gastroenterology.
[99] S. Glaser,et al. Gastrin inhibits secretin-induced ductal secretion by interaction with specific receptors on rat cholangiocytes. , 1997, American journal of physiology. Gastrointestinal and liver physiology.
[100] S. Glaser,et al. Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions. , 1997, The Journal of clinical investigation.
[101] S. Glaser,et al. Bile acids stimulate proliferative and secretory events in large but not small cholangiocytes. , 1997, The American journal of physiology.
[102] S. Glaser,et al. gamma-Interferon inhibits secretin-induced choleresis and cholangiocyte proliferation in a murine model of cirrhosis. , 1997, Journal of hepatology.
[103] J. Boyer,et al. Role of kinases and phosphatases in the regulation of fluid secretion and Cl-/HCO3- exchange in cholangiocytes. , 1997, The American journal of physiology.
[104] M. Swain,et al. Improvement in cholestasis‐associated fatigue with a serotonin receptor agonist using a novel rat model of fatigue assessment , 1997, Hepatology.
[105] S. Glaser,et al. Regrowth of the rat biliary tree after 70% partial hepatectomy is coupled to increased secretin-induced ductal secretion. , 1996, Gastroenterology.
[106] A. Gentilini,et al. Inhibition by pentoxifylline of extracellular signal‐regulated kinase activation by platelet‐derived growth factor in hepatic stellate cells , 1996, British journal of pharmacology.
[107] L. Pannarale,et al. Hepatic microcirculation and peribiliary plexus in experimental biliary cirrhosis: a morphological study. , 1996, Gastroenterology.
[108] Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. , 1996, Endocrine reviews.
[109] I. Stamenkovic,et al. Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan , 1996, The Journal of cell biology.
[110] N. LaRusso,et al. Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes. , 1995, The American journal of physiology.
[111] P. van Eyken,et al. Ductular reaction in the liver. , 1995, Pathology, research and practice.
[112] J. Medina,et al. Immunohistochemical detection of chloride/bicarbonate anion exchangers in human liver , 1994, Hepatology.
[113] N. LaRusso,et al. Upregulation of secretin receptor gene expression in rat cholangiocytes after bile duct ligation. , 1994, The American journal of physiology.
[114] T. Gettys,et al. Secretin activates Cl- channels in bile duct epithelial cells through a cAMP-dependent mechanism. , 1994, The American journal of physiology.
[115] D. Lagunoff,et al. Somatostatin analogue (octreotide) inhibits bile duct epithelial cell proliferation and fibrosis after extrahepatic biliary obstruction. , 1993, The American journal of pathology.
[116] J. Boyer,et al. Effect of secretion on intracellular pH regulation in isolated rat bile duct epithelial cells. , 1993, The Journal of clinical investigation.
[117] P. Gartside,et al. Bile duct changes in alcoholic liver disease. The Veterans Administration Cooperative Study Group. , 1993, Liver.
[118] W. Meyers,et al. Secretin receptors in a new preparation of plasma membranes from intrahepatic biliary epithelium. , 1993, The Journal of surgical research.
[119] M. Iwai,et al. Alteration in sympathetic nerve activity during liver regeneration in rats after partial hepatectomy. , 1992, Journal of the autonomic nervous system.
[120] T. Maudelonde,et al. Estradiol stimulates cell growth and secretion of procathepsin D and a 120-kilodalton protein in the human ovarian cancer cell line BG-1. , 1992, The Journal of clinical endocrinology and metabolism.
[121] H. Stein,et al. Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease. , 1991, The American journal of pathology.
[122] J. Boyer,et al. Mechanisms and regulation of bile secretion , 1991, Hepatology.
[123] R Williams,et al. Hepatic histological findings after transplantation for chronic hepatitis B virus infection, including a unique pattern of fibrosing cholestatic hepatitis , 1991, Hepatology.
[124] V. Desmet,et al. Neuroendocrine features of reactive bile ductules in cholestatic liver disease. , 1990, The American journal of pathology.
[125] H. Stein,et al. Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis. , 1990, Gastroenterology.
[126] H. Stein,et al. Cellular localization of laminin gene transcripts in normal and fibrotic human liver. , 1989, The American journal of pathology.
[127] D. DiPette,et al. Dose-dependent systemic and regional hemodynamic effects of calcitonin gene-related peptide. , 1989, The American journal of the medical sciences.
[128] L. Sarkozi,et al. Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. , 1988, The Journal of clinical investigation.
[129] J. Tippins. CGRP: a novel neuropeptide from the calcitonin gene is the most potent vasodilator known. , 1986, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.
[130] Umezu Kohei,et al. Change of hepatic histamine content during hepatic fibrosis. , 1985 .
[131] H. Morris,et al. Calcitonin gene-related peptide is a potent vasodilator , 1985, Nature.
[132] S. Yuasa,et al. Change of hepatic histamine content during hepatic fibrosis. , 1985, Biochemical pharmacology.
[133] D. Chalbos,et al. Estrogens stimulate cell proliferation and induce secretory proteins in a human breast cancer cell line (T47D). , 1982, The Journal of clinical endocrinology and metabolism.