[14]Subsite preferences of retroviral proteinases
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A. Wlodawer | B. Dunn | A. Gustchina | J. Kay
[1] I. Thompson. Visual cortex: Stars and stripes present the colours , 1985, Nature.
[2] B. Dunn,et al. Design, synthesis and analysis of new synthetic substrates for the aspartic proteinases. , 1985, Biochemical Society transactions.
[3] T. Miyata,et al. Retroviral protease-like sequence in the yeast transposon Ty 1 , 1985, Nature.
[4] William R. Taylor,et al. A structural model for the retroviral proteases , 1987, Nature.
[5] A. Skalka,et al. Activity of avian retroviral protease expressed in Escherichia coli , 1988, Journal of virology.
[6] C. Debouck,et al. Recombinant HIV-1 reverse transcriptase: purification, primary structure, and polymerase/ribonuclease H activities. , 1989, Archives of biochemistry and biophysics.
[7] A. Skalka,et al. Avian retroviral protease and cellular aspartic proteases are distinguished by activities on peptide substrates. , 1989, The Journal of biological chemistry.
[8] A Wlodawer,et al. Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution. , 1989, Science.
[9] M. Jaskólski,et al. Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease. , 1989, Science.
[10] Maria Miller,et al. Crystal structure of a retroviral protease proves relationship to aspartic protease family , 1989, Nature.
[11] B. Dunn,et al. Hydrolysis of a series of synthetic peptide substrates by the human rhinovirus 14 3C proteinase, cloned and expressed in Escherichia coli. , 1989, The Journal of general virology.
[12] M. Navia,et al. Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1 , 1989, Nature.
[13] Brian W. Metcalf,et al. Human immunodeficiency virus protease: A target for aids therapy , 1990 .
[14] Dependence of the P2-S2 stereochemical selectivity of papain on the nature of the catalytic-site chemistry. Quantification of selectivity in the catalysed hydrolysis of the enantiomeric N-acetylphenylalanylglycine 4-nitroanilides. , 1990, The Biochemical journal.
[15] B. Dunn,et al. Viral proteinases: weakness in strength. , 1990, Biochimica et biophysica acta.
[16] V. Kostka,et al. Sub‐site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV‐1 , 1990, FEBS letters.
[17] C. Vlahos,et al. Substitutions at the P2' site of gag p17-p24 affect cleavage efficiency by HIV-1 protease. , 1990, Biochemical and biophysical research communications.
[18] I. Pastan,et al. Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates , 1990, Journal of virology.
[19] I. Weber,et al. Comparison of inhibitor binding in HIV‐1 protease and in non‐viral aspartic proteases: the role of the flap , 1990, FEBS letters.
[20] M. Jaskólski,et al. Structure of the aspartic protease from Rous sarcoma retrovirus refined at 2-A resolution. , 1989, Biochemistry.
[21] D. Norbeck,et al. Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease. , 1990, Science.
[22] R. Dixon,et al. Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution. , 1991, The Journal of biological chemistry.
[23] W. Farmerie,et al. Sensitive, soluble chromogenic substrates for HIV-1 proteinase. , 1990, The Journal of biological chemistry.
[24] V. Kostka,et al. Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases. , 1990, Biochemical and biophysical research communications.
[25] D. Norbeck,et al. Chapter 15. HIV Protease Inhibitors , 1991 .
[26] M. Minnich,et al. Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease. , 1991, Biochemistry.
[27] A. Billich,et al. Analysis of subsite preferences of HIV-1 proteinase using MA/CA junction peptides substituted at the P3-P1' positions. , 1991, Archives of biochemistry and biophysics.
[28] T. Copeland,et al. Comparison of the HIV‐1 and HIV‐2 proteinases using oligopeptide substrates representing cleavage sites in Gag and Gag‐Pol polyproteins , 1991, FEBS letters.
[29] P. Berti,et al. Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites. , 1991, Biochemistry.
[30] I. Weber,et al. Studies on the role of the S4 substrate binding site of HIV proteinases , 1991, FEBS letters.
[31] M. Katharine Holloway,et al. X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry , 1991 .
[32] A Wlodawer,et al. Structural and evolutionary relationships between retroviral and eucaryotic aspartic proteinases. , 1991, Biochemistry.
[33] J. Louis,et al. The effect of salt on the Michaelis Menten constant of the HIV‐1 protease correlates with the Hofmeister series , 1991, FEBS letters.
[34] P. Kraulis. A program to produce both detailed and schematic plots of protein structures , 1991 .
[35] A. Wlodawer,et al. The complexities of AIDS : an assessment of the HIV protease as a therapeutic target , 1991 .
[36] J. Huff,et al. HIV protease: a novel chemotherapeutic target for AIDS. , 1991, Journal of medicinal chemistry.
[37] V. Kostka,et al. Specificity studies on retroviral proteinase from myeloblastosis-associated virus. , 1991, Biochemistry.
[38] J. Kay,et al. Mutating P2 and P1 residues at cleavage junctions in the HIV‐1 pol polyprotein Effects on hydrolysis by HIV‐1 proteinase , 1991, FEBS letters.
[39] Synthesis of homologous peptides using fragment condensation: analogs of an HIV proteinase substrate. , 2009, International journal of peptide and protein research.
[40] B. Dunn,et al. Development of synthetic peptide substrates for the poliovirus 3C proteinase. , 1991, Archives of biochemistry and biophysics.
[41] M. Hatada,et al. Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. , 1991, Journal of medicinal chemistry.
[42] A Wlodawer,et al. Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor. , 1991, Biochemistry.
[43] I. Weber,et al. Comparative analysis of the sequences and structures of HIV‐1 and HIV‐2 proteases , 1991, Proteins.
[44] I. Pichová,et al. Subsite specificity of the proteinase from myeloblastosis associated virus , 1991, FEBS letters.
[45] T. L. Blundell,et al. X-ray analyses of peptide–inhibitor complexes define the structural basis of specificity for human and mouse renins , 1992, Nature.
[46] T. Copeland,et al. Solid phase synthesis of the proteinase of bovine leukemia virus Comparison of its specificity to that of HIV‐2 proteinase , 1992, FEBS letters.
[47] P. Darke,et al. Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design. , 1992, Journal of Medicinal Chemistry.
[48] J. A. Martin,et al. Recent advances in the design of HIV proteinase inhibitors. , 1992, Antiviral research.
[49] A Wlodawer,et al. Analysis of substrate interactions of the Rous sarcoma virus wild type and mutant proteases and human immunodeficiency virus-1 protease using a set of systematically altered peptide substrates. , 1992, The Journal of biological chemistry.
[50] K. Brocklehurst,et al. Variation in the P2-S2 stereochemical selectivity towards the enantiomeric N-acetylphenylalanylglycine 4-nitroanilides among the cysteine proteinases papain, ficin and actinidin. , 1992, The Biochemical journal.
[51] Narmada Thanki,et al. Crystal structure of a complex of HIV‐1 protease with a dihydroxyethylene‐containing inhibitor: Comparisons with molecular modeling , 1992, Protein science : a publication of the Protein Society.
[52] C. Debouck,et al. Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease. , 1992, Biochemistry.
[53] B. Dunn,et al. Substrate specificity and inhibitors of aspartic proteinases. , 1992, Scandinavian journal of clinical and laboratory investigation. Supplementum.
[54] An engineered retroviral proteinase from myeloblastosis associated virus acquires pH dependence and substrate specificity of the HIV‐1 proteinase. , 1992, The EMBO journal.
[55] J. Louis,et al. Kinetic and modeling studies of S3-S3' subsites of HIV proteinases. , 1992, Biochemistry.
[56] Intrinsic activity of precursor forms of HIV‐1 proteinase , 1992, FEBS letters.
[57] A M Hassell,et al. Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays. , 1992, Biochemistry.
[58] A Wlodawer,et al. Mutations that alter the activity of the Rous sarcoma virus protease. , 1992, The Journal of biological chemistry.
[59] A. Wlodawer,et al. Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites. , 1992, Biochemistry.
[60] A. Wlodawer,et al. Structure-based inhibitors of HIV-1 protease. , 1993, Annual review of biochemistry.
[61] B. Dunn,et al. Interactions of substrates and inhibitors with a family of tethered HIV-1 and HIV-2 homo- and heterodimeric proteinases. , 1994, The Journal of biological chemistry.
[62] A Wlodawer,et al. Energy calculations and analysis of HIV-1 protease-inhibitor crystal structures. , 1994, Protein engineering.