Hemisphere‐dependent Cognitive Performances in Epileptic Patients

Summary: Short‐term memory (STM), long‐term memory (LTM), and recency judgment were investigated in 75 right‐handed nonaphasic patients without visual deficits who had epileptic foci localized in one of four different regions of the brain: right temporal lobe, left temporal lobe, right frontal lobe, and left frontal lobe. The results led to the following conclusions: (1) left temporal lesions yielded comparatively greater impairment for the verbal LTM task, whereas right temporal lesions were more disruptive for the spatial LTM task; (2) no significant differences between left‐ and right‐brain‐damaged patients in STM tasks were obtained; (3) left frontal lesions yielded deficits in a recency task in accordance with hemispheric specialization; (4) only prolonged epileptic syndroipes impaired neuropsychological performance in those tests; (5) comparisons between male and female patients and between those with and without clear evidence of a structural lesion did not reach statistical significance.

[1]  B. Milner MEMORY AND THE MEDIAL TEMPORAL REGIONS OF THE BRAIN , 1970 .

[2]  R. Sperry,et al.  Memory impairment after commissurotomy in man. , 1974, Brain : a journal of neurology.

[3]  B. Milner,et al.  Interhemispheric differences in the localization of psychological processes in man. , 1971, British medical bulletin.

[4]  Brenda Milner,et al.  Visually-guided maze learning in man: effects of bilateral hippocampal, bilateral frontal, and unilateral cerebral lesions , 1965 .

[5]  G. Rizzolatti,et al.  Hemispheric Superiority in Reaction Time to Faces: A Sex Difference , 1977, Cortex.

[6]  H. Lansdell The Use of Factor Scores from the Wechsler-Bellevue Scale of Intelligence in Assessing Patients with Temporal Lobe Removals , 1968 .

[7]  D. M. Sterne The Benton, Porteus and WAIS digit span tests with normal and brain-injured subjects. , 1969, Journal of clinical psychology.

[8]  H. Gastaut,et al.  Computerized Transverse Axial Tomography in Epilepsy* , 1976, Epilepsia.

[9]  N. Butters,et al.  Short term memory disorders following temporal lobe removals in humans. , 1972, Cortex; a journal devoted to the study of the nervous system and behavior.

[10]  H. Spinnler,et al.  Immediate and Delayed Recognition of Nonsense Figures in Patients with Unilateral Hemisphere Damage , 1969 .

[11]  Brodie Hughes,et al.  MISSILE WOUNDS OF THE BRAIN A Study of Psychological Deficits , 1970 .

[12]  T. Rasmussen,et al.  INTRACAROTID INJECTION OF SODIUM AMYTAL FOR THE LATERALIZATION OF CEREBRAL SPEECH DOMINANCE EXPERIMENTAL AND CLINICAL OBSERVATIONS , 1960 .

[13]  D. Hebb Distinctive features of learning in the higher animal , 1961 .

[14]  J. Mcglone,et al.  Sex differences in the cerebral organization of verbal functions in patients with unilateral brain lesions. , 1977, Brain : a journal of neurology.

[15]  P J Hogarth,et al.  The physiological basis of memory. , 1966, Advancement of science.

[16]  Paolo Nichelli,et al.  Verbal and Non-Verbal Short-Term Memory Impairment Following Hemispheric Damage , 1975, Cortex.

[17]  G. Rizzolatti,et al.  Hemispheric differences in the discrimination of line orientation. , 1974, Neuropsychologia.

[18]  A. Baddeley,et al.  Amnesia and the distinction between long- and short-term memory. , 1970 .

[19]  E K Warrington,et al.  Amnesia and memory for visual location. , 1974, Neuropsychologia.

[20]  H. Fairweather Sex differences in cognition , 1976, Cognition.

[21]  G. Rizzolatti,et al.  Opposite superiorities of the right and left cerebral hemispheres in discriminative reaction time to physiognomical and alphabetical material. , 1971, Brain : a journal of neurology.

[22]  E. Renzi,et al.  Spatial Memory and Hemispheric Locus of Lesion , 1977, Cortex.

[23]  E K Warrington,et al.  The anatomical localisation of selective impairment of auditory verbal short-term memory. , 1971, Neuropsychologia.

[24]  D. Drachman,et al.  Memory and the hippocampal complex. II. Is memory a multiple process , 1966 .

[25]  L. Costa The Relation of Visuospatial Dysfunction to Digit Span Performance in Patients with Cerebral Lesions , 1975, Cortex.