Expanded Polyglutamine Protein Forms Nuclear Inclusions and Causes Neural Degeneration in Drosophila

[1]  S. Tsuji,et al.  Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch , 1998, Nature Genetics.

[2]  R. Albin,et al.  Ectopically Expressed CAG Repeats Cause Intranuclear Inclusions and a Progressive Late Onset Neurological Phenotype in the Mouse , 1997, Cell.

[3]  C A Ross,et al.  Intranuclear Neuronal Inclusions: A Common Pathogenic Mechanism for Glutamine-Repeat Neurodegenerative Diseases? , 1997, Neuron.

[4]  M. Hayden,et al.  Rethinking genotype and phenotype correlations in polyglutamine expansion disorders. , 1997, Human molecular genetics.

[5]  H. Zoghbi,et al.  The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1 , 1997, Nature.

[6]  S. W. Davies,et al.  Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. , 1997, Science.

[7]  S. Carroll,et al.  Fossils, genes and the evolution of animal limbs , 1997, Nature.

[8]  Hans Lehrach,et al.  Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo , 1997, Cell.

[9]  K. Fischbeck,et al.  Intranuclear Inclusions of Expanded Polyglutamine Protein in Spinocerebellar Ataxia Type 3 , 1997, Neuron.

[10]  Mark Turmaine,et al.  Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation , 1997, Cell.

[11]  D. Housman,et al.  The complex pathology of trinucleotide repeats. , 1997, Current opinion in cell biology.

[12]  K. Fischbeck,et al.  Machado‐Joseph disease gene product is a cytoplasmic protein widely expressed in brain , 1997, Annals of neurology.

[13]  M. Freeman,et al.  Reiterative Use of the EGF Receptor Triggers Differentiation of All Cell Types in the Drosophila Eye , 1996, Cell.

[14]  S. W. Davies,et al.  Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice , 1996, Cell.

[15]  J. Abrams,et al.  grim, a novel cell death gene in Drosophila. , 1996, Genes & development.

[16]  S. Narumiya,et al.  Expanded polyglutamine in the Machado–Joseph disease protein induces cell death in vitro and in vivo , 1996, Nature Genetics.

[17]  Alexandra Durr,et al.  Spinocerebellar ataxia 3 and machado‐joseph disease: Clinical, molecular, and neuropathological features , 1996, Annals of neurology.

[18]  T. Tully,et al.  CREB and the formation of long-term memory , 1996, Current Opinion in Neurobiology.

[19]  A. Mccarthy.  Development , 1996, Current Opinion in Neurobiology.

[20]  H. Steller,et al.  Cell Killing by the Drosophila Gene reaper , 1996, Science.

[21]  T D Bird,et al.  Spinocerebellar ataxia type 1 and Machado-Joseph disease: incidence of CAG expansions among adult-onset ataxia patients from 311 families with dominant, recessive, or sporadic ataxia. , 1995, American journal of human genetics.

[22]  H. Steller,et al.  The head involution defective gene of Drosophila melanogaster functions in programmed cell death. , 1995, Genes & development.

[23]  L. Schöls,et al.  Trinucleotide expansion within the MJD1 gene presents clinically as spinocerebellar ataxia and occurs most frequently in German SCA patients. , 1995, Human molecular genetics.

[24]  C. Goodman,et al.  Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance , 1994, Neuron.

[25]  M. Pericak-Vance,et al.  The Haw River Syndrome: Dentatorubropallidoluysian atrophy (DRPLA) in an African–American family , 1994, Nature Genetics.

[26]  G M Rubin,et al.  Expression of baculovirus P35 prevents cell death in Drosophila. , 1994, Development.

[27]  Gerald M. Rubin,et al.  The activities of two Ets-related transcription factors required for drosophila eye development are modulated by the Ras/MAPK pathway , 1994, Cell.

[28]  M. C. Ellis,et al.  Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. , 1993, Development.

[29]  N. Perrimon,et al.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. , 1993, Development.

[30]  T. Venkatesh.  Neuronal development in the Drosophila retina. , 1993, Journal of neurobiology.

[31]  Seymour Benzer,et al.  The eyes absent gene: Genetic control of cell survival and differentiation in the developing Drosophila eye , 1993, Cell.

[32]  W. Gelbart,et al.  An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila. , 1991, Development.

[33]  R. Cagan,et al.  The emergence of order in the Drosophila pupal retina. , 1989, Developmental biology.

[34]  R. Schuh,et al.  Pattern formation in Drosophila. , 1989, Seminars in cell biology.

[35]  K. White,et al.  The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages. , 1988, Developmental biology.

[36]  S. Benzer,et al.  Neuronal development in the drosophila retina: Monoclonal antibodies as molecular probes , 1984, Cell.

[37]  G. Rubin,et al.  The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene , 1983, Cell.

[38]  S. Benzer,et al.  Development of the Drosophila retina, a neurocrystalline lattice. , 1976, Developmental biology.

[39]  M. Bate,et al.  The development of Drosophila melanogaster , 2009 .

[40]  Shigenobu Nakamura,et al.  CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1 , 1994, Nature Genetics.

[41]  G. Rubin,et al.  Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. , 1994, Annual review of neuroscience.

[42]  H. Steller,et al.  Programmed cell death during Drosophila embryogenesis. , 1993, Development.

[43]  W. Gelbart,et al.  The relationship of decapentaplegic and engrailed expression in Drosophila imaginal disks: do these genes mark the anterior-posterior compartment boundary? , 1991, Development.