Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.

[1]  R. Ley,et al.  The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine , 2011, Science.

[2]  B. Pulendran,et al.  Dendritic cell control of tolerogenic responses , 2011, Immunological reviews.

[3]  A. Diefenbach,et al.  Control of epithelial cell function by interleukin‐22‐producing RORγt+ innate lymphoid cells , 2011, Immunology.

[4]  S. Rutz,et al.  Regulation and functions of the IL-10 family of cytokines in inflammation and disease. , 2011, Annual review of immunology.

[5]  D. Artis,et al.  CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut. , 2011, Immunity.

[6]  N. Socci,et al.  Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans. , 2010, The Journal of clinical investigation.

[7]  J. D. Di Santo,et al.  Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2. , 2010, Immunity.

[8]  F. Powrie,et al.  Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells , 2010, Immunity.

[9]  O. Pabst,et al.  The puzzle of intestinal lamina propria dendritic cells and macrophages , 2010, European journal of immunology.

[10]  J. Sirard,et al.  TLR5 Signaling Stimulates the Innate Production of IL-17 and IL-22 by CD3negCD127+ Immune Cells in Spleen and Mucosa , 2010, The Journal of Immunology.

[11]  F. Powrie,et al.  Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells , 2010, European journal of immunology.

[12]  S. Mazmanian,et al.  Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota , 2010, Proceedings of the National Academy of Sciences.

[13]  Steffen Jung,et al.  Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria , 2010, Nature Reviews Immunology.

[14]  J. Renauld,et al.  IL-22 defines a novel immune pathway of antifungal resistance , 2010, Mucosal Immunology.

[15]  Richard A Flavell,et al.  Bacterial flagellin stimulates Toll-like receptor 5-dependent defense against vancomycin-resistant Enterococcus infection. , 2010, The Journal of infectious diseases.

[16]  T. Hohl,et al.  Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection. , 2009, Cell host & microbe.

[17]  Dan R. Littman,et al.  Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria , 2009, Cell.

[18]  F. Ginhoux,et al.  Origin of the lamina propria dendritic cell network. , 2009, Immunity.

[19]  Steffen Jung,et al.  Intestinal lamina propria dendritic cell subsets have different origin and functions. , 2009, Immunity.

[20]  K. Mills,et al.  Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. , 2009, Immunity.

[21]  M. Veldhoen,et al.  Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. , 2009, Immunity.

[22]  M. Neurath,et al.  STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing , 2009, The Journal of experimental medicine.

[23]  K. Takeda,et al.  Regulatory mechanisms of immune responses to intestinal bacteria , 2009, Mucosal Immunology.

[24]  C. Tato,et al.  Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22 , 2009, The Journal of experimental medicine.

[25]  L. Eckmann,et al.  Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface , 2008, Proceedings of the National Academy of Sciences.

[26]  A. Hidrón,et al.  Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007 , 2008, Infection Control & Hospital Epidemiology.

[27]  Ronald P. DeMatteo,et al.  Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits , 2008, Nature.

[28]  R. Knight,et al.  Worlds within worlds: evolution of the vertebrate gut microbiota , 2008, Nature Reviews Microbiology.

[29]  Hiroshi Kiyono,et al.  Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5 , 2008, Nature Immunology.

[30]  M. Rojas,et al.  Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation1 , 2008, The Journal of Immunology.

[31]  A. Osterman,et al.  An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models , 2008, Science.

[32]  S. Sa,et al.  Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens , 2008, Nature Medicine.

[33]  M. Fei,et al.  IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia , 2008, Nature Medicine.

[34]  B. Becher,et al.  IL-22 Is Expressed by Th17 Cells in an IL-23-Dependent Fashion, but Not Required for the Development of Autoimmune Encephalomyelitis1 , 2007, The Journal of Immunology.

[35]  A. Murphy,et al.  Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. , 2007, Immunity.

[36]  Y. Belkaid,et al.  A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism , 2007, The Journal of experimental medicine.

[37]  F. Powrie,et al.  Interleukin-23 drives innate and T cell–mediated intestinal inflammation , 2006, The Journal of experimental medicine.

[38]  L. Hooper,et al.  Symbiotic Bacteria Direct Expression of an Intestinal Bactericidal Lectin , 2006, Science.

[39]  R. Locksley,et al.  Visualization of IL-12/23p40 In Vivo Reveals Immunostimulatory Dendritic Cell Migrants that Promote Th1 Differentiation1 , 2006, The Journal of Immunology.

[40]  C. Coban,et al.  Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells , 2006, Nature Immunology.

[41]  C. Donskey The role of the intestinal tract as a reservoir and source for transmission of nosocomial pathogens. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[42]  S. Targan,et al.  Bacterial flagellin is a dominant antigen in Crohn disease , 2004 .

[43]  M. Neurath,et al.  Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. , 2003, The Journal of clinical investigation.

[44]  T. Pineau,et al.  Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor , 1995, Science.

[45]  H. Spits,et al.  The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling , 2011, Nature Immunology.

[46]  Andreas Diefenbach,et al.  RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells , 2009, Nature Immunology.

[47]  S. Akira,et al.  Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. , 1999, Immunity.