Miniaturized signal conditioning system for Kapton/sup (R)/-based biopotential and ion-selective electrode arrays

A miniaturized signal conditioning system for biopotential and ion-selective cardiovascular microelectrodes is presented. This prototype system will serve as the basis for an implantable, inductively powered biotelemetry system for in vivo measurements of cardiac biopotentials and ionic activities. A SPICE system model is being proposed to facilitate the design process of the system components-electrodes, signal conditioning chip, and interconnections. A prototype of the signal conditioning chip has been fabricated and tested. Thermosonic wirebonding and goldplating have been investigated as a method to interconnect this chip with the electrode array.

[1]  H. T. Nagle,et al.  Transmission line models for ion-selective membranes in cardiology simulated with SPICE , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[2]  Gabor C. Temes,et al.  An 8-b 1.3-MHz successive-approximation A/D converter , 1990 .

[3]  John H. Lau,et al.  Chip on Board: Technologies for Multichip Modules , 1995 .