Hepatocyte growth factor/scatter factor—Met signaling in tumorigenicity and invasion/metastasis

[1]  T. Shuin,et al.  Overexpression of c-met proto-oncogene associated with chromophilic renal cell carcinoma with papillary growth , 1998, Virchows Archiv.

[2]  G. V. Vande Woude,et al.  Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells. , 1996, Oncogene.

[3]  G. V. Vande Woude,et al.  Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network , 1996, Molecular and cellular biology.

[4]  R. Ball,et al.  Hepatocyte growth factor/scatter factor is present in most pleural effusion fluids from cancer patients. , 1996, British Journal of Cancer.

[5]  N. Rahimi,et al.  Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[6]  W. Birchmeier,et al.  Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland , 1995, The Journal of cell biology.

[7]  Carmen Birchmeier,et al.  Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud , 1995, Nature.

[8]  P. Troncoso,et al.  c-met proto-oncogene expression in benign and malignant human prostate tissues. , 1995, The Journal of urology.

[9]  J. Siegfried,et al.  Stimulatory effects of hepatocyte growth factor on normal and neoplastic human bronchial epithelial cells. , 1995, The American journal of physiology.

[10]  L. Donehower,et al.  Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients. , 1995, Cancer research.

[11]  A. Bardelli,et al.  The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. , 1995, Oncogene.

[12]  K. Miyazawa,et al.  Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator. , 1995, European journal of biochemistry.

[13]  G. H. Weiss,et al.  Expression of scatter factor in human bladder carcinoma. , 1995, Journal of the National Cancer Institute.

[14]  S. Aparício,et al.  A role for HGF/SF in neural induction and its expression in Hensen's node during gastrulation. , 1995, Development.

[15]  R. Poulsom,et al.  Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer. , 1995, Cancer research.

[16]  Tetsuo Noda,et al.  Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor , 1995, Nature.

[17]  M. Sharpe,et al.  Scatter factor/hepatocyte growth factor is essential for liver development , 1995, Nature.

[18]  P. Lollini,et al.  The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit. , 1995, Oncogene.

[19]  L. Orci,et al.  Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. , 1995, Journal of cell science.

[20]  M. Noble,et al.  Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros , 1995, The Journal of cell biology.

[21]  K. Matsumoto,et al.  Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. , 1994, The Journal of biological chemistry.

[22]  H. Friess,et al.  Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer. , 1994, Cancer research.

[23]  A. Joseph,et al.  Regulation of scatter factor production via a soluble inducing factor , 1994, The Journal of cell biology.

[24]  K.,et al.  The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras. , 1994, The Journal of biological chemistry.

[25]  P Zola,et al.  Overexpression of the MET/HGF receptor in ovarian cancer , 1994, International journal of cancer.

[26]  K. Matsumoto,et al.  Autocrine stimulation of motility in SBC-5 human lung carcinoma cells by a two-kringle variant of HGF. , 1994, Cancer letters.

[27]  E. Rosen,et al.  Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[28]  K. Matsumoto,et al.  Involvement of hepatocyte growth factor in kidney development. , 1994, Developmental biology.

[29]  M. Bhargava,et al.  Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor , 1994, International journal of cancer.

[30]  G. V. Vande Woude,et al.  Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[31]  E. Rosen,et al.  Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epi , 1994, The Journal of clinical investigation.

[32]  A. Bardelli,et al.  A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family , 1994, Cell.

[33]  T. Nakamura,et al.  Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. , 1994, Oncogene.

[34]  M. Ogawa,et al.  Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer. , 1994, Cancer research.

[35]  S. Byers,et al.  Hepatocyte growth factor stimulates invasion across reconstituted basement membranes by a new human small intestinal cell line , 1994, Clinical & Experimental Metastasis.

[36]  T. Nakamura,et al.  Purification and characterization of hepatocyte growth factor (HGF)-converting enzyme: activation of pro-HGF. , 1994, Biochemical and biophysical research communications.

[37]  G. V. Vande Woude,et al.  The Met proto-oncogene mesenchymal to epithelial cell conversion. , 1994, Science.

[38]  J. Rubin,et al.  Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product. , 1993, Biochimica et biophysica acta.

[39]  G. V. Vande Woude,et al.  Met expression and sarcoma tumorigenicity. , 1993, Cancer research.

[40]  S. Hirohashi,et al.  Immunohistochemical Detection of Hepatocyte Growth Factor/Scatter Factor in Human Cancerous and Inflammatory Lesions of Various Organs , 1993, Japanese journal of cancer research : Gann.

[41]  K. Matsumoto,et al.  Hepatocyte growth factor transforms immortalized mouse liver epithelial cells. , 1993, Oncogene.

[42]  C. Birchmeier,et al.  Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development , 1993, The Journal of cell biology.

[43]  P. Comoglio,et al.  Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression. , 1993, British Journal of Cancer.

[44]  E. Villa-Moruzzi,et al.  A protein tyrosine phosphatase activity associated with the hepatocyte growth factor/scatter factor receptor. , 1993, The Journal of biological chemistry.

[45]  A. Bardelli,et al.  A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor , 1993, Molecular and cellular biology.

[46]  T. Nakamura,et al.  Tumorigenesis induced by coexpression of human hepatocyte growth factor and the human met protooncogene leads to high levels of expression of the ligand and receptor. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[47]  T. Nakamura,et al.  Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[48]  P. Comoglio,et al.  Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger. , 1993, The Journal of biological chemistry.

[49]  T. Nakamura,et al.  Regulation of fibroblast hepatocyte growth factor/scatter factor expression by human breast carcinoma cell lines and peptide growth factors. , 1993, Cancer research.

[50]  H. Kleinman,et al.  Scatter factor induces blood vessel formation in vivo. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[51]  F. Blasi Urokinase and urokinase receptor: A paracrine/autocrine system regulating cell migration and invasiveness , 1993 .

[52]  T. Nakamura,et al.  Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts. , 1993, British Journal of Cancer.

[53]  T. Nakamura,et al.  Proteolytic activation of a single-chain precursor of hepatocyte growth factor by extracellular serine-protease. , 1992, Biochemical and biophysical research communications.

[54]  W. Birchmeier,et al.  Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. , 1992, The EMBO journal.

[55]  V. Ellis,et al.  The Urokinase Receptor: Involvement in Cell Surface Proteolysis and Cancer Invasion , 1992, Annals of the New York Academy of Sciences.

[56]  W. Birchmeier,et al.  A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[57]  M. Pierotti,et al.  Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas. , 1992, Oncogene.

[58]  H. Ito,et al.  Frequent amplification of the c-met gene in scirrhous type stomach cancer. , 1992, Biochemical and biophysical research communications.

[59]  T. Nakamura,et al.  Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor , 1992, Molecular and cellular biology.

[60]  L. Naldini,et al.  Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth , 1992, The Journal of cell biology.

[61]  L. Orci,et al.  Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells. , 1992, The Journal of biological chemistry.

[62]  A. Bardelli,et al.  Autophosphorylation promotes complex formation of recombinant hepatocyte growth factor receptor with cytoplasmic effectors containing SH2 domains. , 1992, Oncogene.

[63]  E. Medico,et al.  The c-met/HGF receptor in human tumours , 1992, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[64]  G. V. Vande Woude,et al.  The met proto-oncogene receptor and lumen formation. , 1992, Science.

[65]  H. Tsubouchi,et al.  The presence of scatter factor in patients with metastatic spread to the pleura. , 1992, British Journal of Cancer.

[66]  P. Godowski,et al.  Structure‐function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding. , 1992, The EMBO journal.

[67]  L. Orci,et al.  Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor , 1991, Cell.

[68]  L. Cantley,et al.  The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase. , 1991, The Journal of biological chemistry.

[69]  E Medico,et al.  Expression of the Met/HGF receptor in normal and neoplastic human tissues. , 1991, Oncogene.

[70]  M. Reiss,et al.  Tumor necrosis factor stimulates epithelial tumor cell motility. , 1991, Cancer research.

[71]  P. Comoglio,et al.  The receptor encoded by the human C‐MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors , 1991, International journal of cancer.

[72]  M. Mareel,et al.  Mechanisms of Invasion and Metastasis , 1991 .

[73]  J. Rubin,et al.  A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[74]  S. Hirono,et al.  Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme‐linked immunosorbent assay , 1991, Hepatology.

[75]  J Vandekerckhove,et al.  Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells , 1990, The Journal of cell biology.

[76]  G. V. Vande Woude,et al.  Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[77]  J. Folkman What is the evidence that tumors are angiogenesis dependent? , 1990, Journal of the National Cancer Institute.

[78]  Toshikazu Nakamura,et al.  Purification and subunit structure of hepatocyte growth factor from rat platelets , 1987, FEBS letters.

[79]  M. Braun,et al.  Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[80]  Michael Stoker,et al.  Scatter factor is a fibroblast-derived modulator of epithelial cell mobility , 1987, Nature.

[81]  C. Cooper,et al.  Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts. , 1986, The EMBO journal.

[82]  C. Cooper,et al.  Mechanism of met oncogene activation , 1986, Cell.

[83]  L. Liotta,et al.  Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell. , 1985, The American journal of pathology.

[84]  C. Cooper,et al.  Molecular cloning of a new transforming gene from a chemically transformed human cell line , 1984, Nature.

[85]  C. Cooper,et al.  New method for detecting cellular transforming genes. , 1982, Science.

[86]  D. Lowy,et al.  A quantitative in vitro focus assay for bovine papilloma virus. , 1980, Virology.

[87]  D. Lowy,et al.  Helper-independent transformation by unintegrated Harvey sarcoma virus DNA , 1978, Journal of virology.

[88]  J. Rhim,et al.  Transformation of human osteosarcoma cells by a chemical carcinogen. , 1975, Journal of the National Cancer Institute.

[89]  J. Kondo,et al.  A novel protease obtained from FBS-containing culture supernatant, that processes single chain form hepatocyte growth factor to two chain form in serum-free culture , 2006, Cytotechnology.

[90]  A. Tannapfel,et al.  Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines , 2004, Virchows Archiv.

[91]  B. Elliott,et al.  Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma. , 1996, The American journal of pathology.

[92]  E. Rosen,et al.  Regulation of scatter factor (hepatocyte growth factor) production by tumor-stroma interaction. , 1995, EXS.

[93]  K. Miyazawa,et al.  Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. , 1994, Cell adhesion and communication.

[94]  K. Miyazawa,et al.  Tyrosine Phosphorylation of β-Catenin and Plakoglobin Enhanced by Hepatocyte Growth Factor and Epidermal Growth Factor in Human Carcinoma Cells , 1994 .

[95]  H. Birkedal‐Hansen,et al.  Matrix metalloproteinases: a review. , 1993, Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists.

[96]  N. Shima,et al.  Tumor cytotoxic activity of HGF-SF. , 1993, EXS.

[97]  G. Rodrigues,et al.  Isoforms of the met receptor tyrosine kinase. , 1993, EXS.

[98]  K. Matsumoto,et al.  Roles of HGF as a pleiotropic factor in organ regeneration. , 1993, EXS.

[99]  M. Sharpe,et al.  Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells. , 1993, Symposia of the Society for Experimental Biology.

[100]  L. Liotta,et al.  Tumor cell interactions with the extracellular matrix during invasion and metastasis. , 1993, Annual review of cell biology.

[101]  G. V. Vande Woude,et al.  Signal transduction in c-met mediated motogenesis. , 1993, EXS.

[102]  R. Halaban,et al.  Scatter factor and hepatocyte growth factor: activities, properties, and mechanism. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[103]  K. Matsumoto,et al.  Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions. , 1992, Critical reviews in oncogenesis.

[104]  M. Barbacid,et al.  C127 cells resistant to transformation by tyrosine protein kinase oncogenes. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[105]  D. Rifkin,et al.  Cell-associated plasminogen activation: regulation and physiological functions. , 1988, Annual review of cell biology.

[106]  C. Cooper,et al.  Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines. , 1984, Cancer research.