Cardiac Mitochondrial PTEN-L determines cell fate between apoptosis and survival during chronic alcohol consumption

[1]  G. Mithieux,et al.  Chronic intake of 4-Methylimidazole induces Hyperinsulinemia and Hypoglycaemia via Pancreatic Beta Cell Hyperplasia and Glucose Dyshomeostasis , 2018, Scientific Reports.

[2]  K. Lim,et al.  PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy , 2018, Cell Research.

[3]  K. S. Rajan,et al.  Egr‐1 mediated cardiac miR‐99 family expression diverges physiological hypertrophy from pathological hypertrophy , 2018, Experimental cell research.

[4]  J. Bangsbo,et al.  PGC-1α and exercise intensity dependent adaptations in mouse skeletal muscle , 2017, PloS one.

[5]  J. Rajendhran,et al.  Cardiac mitochondrial dynamics: miR-mediated regulation during cardiac injury. , 2017, Journal of molecular and cellular cardiology.

[6]  Shi-Kun Liu,et al.  Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation , 2017, Acta Pharmacologica Sinica.

[7]  J. Hoek,et al.  Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity , 2017, Proceedings of the National Academy of Sciences.

[8]  M. Okada,et al.  Canstatin inhibits isoproterenol-induced apoptosis through preserving mitochondrial morphology in differentiated H9c2 cardiomyoblasts , 2016, Apoptosis.

[9]  J. Kalbfleisch,et al.  Attenuation of cardiac dysfunction and remodeling of myocardial infarction by microRNA-130a are mediated by suppression of PTEN and activation of PI3K dependent signaling. , 2015, Journal of molecular and cellular cardiology.

[10]  P. Arthur,et al.  Ethanol Dose- and Time-dependently Increases α and β Subunits of Mitochondrial ATP Synthase of Cultured Neonatal Rat Cardiomyocytes. , 2015, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

[11]  J. Fernandez-Solà.  Cardiovascular risks and benefits of moderate and heavy alcohol consumption , 2015, Nature Reviews Cardiology.

[12]  D. Hausenloy,et al.  Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular disease , 2015, European journal of pharmacology.

[13]  Jiliang Wu,et al.  Resveratrol attenuates high glucose-induced oxidative stress and cardiomyocyte apoptosis through AMPK , 2015, Molecular and Cellular Endocrinology.

[14]  L. Scorrano,et al.  Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. , 2015, Cell metabolism.

[15]  Xiaodong Wang,et al.  Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis , 2014, Proceedings of the National Academy of Sciences.

[16]  L. Scorrano,et al.  Akt protects the heart against ischaemia-reperfusion injury by modulating mitochondrial morphology , 2014, Thrombosis and Haemostasis.

[17]  A. Shah,et al.  Redox regulation of cardiac hypertrophy. , 2014, Journal of molecular and cellular cardiology.

[18]  G. Haddad,et al.  Acute alcohol modulates cardiac function as PI3K/Akt regulates oxidative stress. , 2014, Alcoholism, clinical and experimental research.

[19]  A. Zorzano,et al.  Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway , 2014, Journal of Cell Science.

[20]  M. Funaki,et al.  Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance. , 2014, Experimental cell research.

[21]  S. Archer,et al.  Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[22]  J. Campos,et al.  Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction , 2013, Journal of the American Heart Association.

[23]  G. Haddad,et al.  The good, the bad, and the ugly with alcohol use and abuse on the heart. , 2013, Alcoholism, clinical and experimental research.

[24]  Jennifer S. Yu,et al.  A Secreted PTEN Phosphatase That Enters Cells to Alter Signaling and Survival , 2013, Science.

[25]  Mark A Sussman,et al.  Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation , 2013, Proceedings of the National Academy of Sciences.

[26]  J. Naval,et al.  Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation* , 2013, The Journal of Biological Chemistry.

[27]  T. Netticadan,et al.  Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury. , 2012, Archives of biochemistry and biophysics.

[28]  A. M. van der Bliek,et al.  Mitochondrial Fission, Fusion, and Stress , 2012, Science.

[29]  O. Shupliakov,et al.  Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission , 2011, The EMBO journal.

[30]  D. Xing,et al.  Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission–fusion proteins , 2011, The FEBS journal.

[31]  Zhenyu Shen,et al.  PTEN inhibitors cause a negative inotropic and chronotropic effect in mice. , 2011, European journal of pharmacology.

[32]  I. Gostimskaya,et al.  Preparation of Highly Coupled Rat Heart Mitochondria , 2010, Journal of visualized experiments : JoVE.

[33]  R. Woscholski,et al.  Characterisation of the PTEN inhibitor VO-OHpic , 2010, Journal of chemical biology.

[34]  Sang-Bing Ong,et al.  Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury , 2010, Circulation.

[35]  E. Rimm,et al.  Alcohol Intake and Risk of Coronary Heart Disease in Younger, Middle-Aged, and Older Adults , 2010, Circulation.

[36]  M. Louhelainen,et al.  Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes , 2010, Blood pressure.

[37]  Qizhi Gong,et al.  Mitochondrial OPA1, apoptosis, and heart failure. , 2009, Cardiovascular research.

[38]  W. Zong,et al.  Execution of Superoxide-Induced Cell Death by the Proapoptotic Bcl-2-Related Proteins Bid and Bak , 2009, Molecular and Cellular Biology.

[39]  D. Wallace,et al.  Heterozygous Mutation of Opa1 in Drosophila Shortens Lifespan Mediated through Increased Reactive Oxygen Species Production , 2009, PloS one.

[40]  X. Yao,et al.  Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspring. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[41]  J. Wands,et al.  Acute ethanol exposure inhibits insulin signaling in the liver , 2007, Hepatology.

[42]  D. Chan,et al.  OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L , 2007, The Journal of cell biology.

[43]  Craig Brooks,et al.  Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins , 2007, Proceedings of the National Academy of Sciences.

[44]  J. Estaquier,et al.  Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis , 2007, Cell Death and Differentiation.

[45]  L. Scorrano,et al.  Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts , 2007, Nature Protocols.

[46]  J. Martinou,et al.  Inhibiting the Mitochondrial Fission Machinery Does Not Prevent Bax/Bak-Dependent Apoptosis , 2006, Molecular and Cellular Biology.

[47]  Richard Ila,et al.  Chronic-alcohol exposure alters IGF1 signaling in H9c2 cells via changes in PKC delta. , 2006, Alcohol.

[48]  C. Blackstone,et al.  Release of OPA1 during Apoptosis Participates in the Rapid and Complete Release of Cytochrome c and Subsequent Mitochondrial Fragmentation* , 2005, Journal of Biological Chemistry.

[49]  D. Chang,et al.  Smac/DIABLO and cytochrome c are released from mitochondria through a similar mechanism during UV-induced apoptosis , 2005, Apoptosis.

[50]  A. M. van der Bliek,et al.  Loss of the Intermembrane Space Protein Mgm1/OPA1 Induces Swelling and Localized Constrictions along the Lengths of Mitochondria* , 2004, Journal of Biological Chemistry.

[51]  C. Anuradha,et al.  Taurine restores ethanol-induced depletion of antioxidants and attenuates oxidative stress in rat tissues , 2004, Amino Acids.

[52]  J. Wands,et al.  Potential role of PTEN phosphatase in ethanol‐impaired survival signaling in the liver , 2003, Hepatology.

[53]  M. McNiven,et al.  The Mitochondrial Protein hFis1 Regulates Mitochondrial Fission in Mammalian Cells through an Interaction with the Dynamin-Like Protein DLP1 , 2003, Molecular and Cellular Biology.

[54]  J. Wands,et al.  Ethanol Impairs Insulin-stimulated Neuronal Survival in the Developing Brain , 2003, Journal of Biological Chemistry.

[55]  G. Lenaers,et al.  Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis* , 2003, The Journal of Biological Chemistry.

[56]  P. Frachon,et al.  Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. , 2002, Molecular biology of the cell.

[57]  M. Piano.  Alcohol and heart failure. , 2002, Journal of cardiac failure.

[58]  M. Piano.  Alcoholic cardiomyopathy: incidence, clinical characteristics, and pathophysiology. , 2002, Chest.

[59]  A. M. van der Bliek,et al.  Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. , 2001, Molecular biology of the cell.

[60]  A. M. van der Bliek,et al.  A Human Dynamin-related Protein Controls the Distribution of Mitochondria , 1998, The Journal of cell biology.

[61]  L. Bakeeva,et al.  Ultrastructure of mitochondrial reticulum of human cardiomyocytes in alcohol cardiomyopathy. , 1997, Biochemistry. Biokhimiia.

[62]  J. Marín-García,et al.  Heart mitochondria response to alcohol is different than brain and liver. , 1995, Alcoholism, clinical and experimental research.

[63]  G. Schultz,et al.  Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart. , 1991, Circulation research.

[64]  K. Yagi,et al.  Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. , 1979, Analytical biochemistry.

[65]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[66]  J. Sadoshima,et al.  Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system. , 2015, Journal of molecular and cellular cardiology.

[67]  M. Cobo-Marcos,et al.  Alcoholic cardiomyopathy. , 2014, World journal of cardiology.

[68]  Alfonso Bellacosa,et al.  A Secreted PTEN Phosphatase That Enters Cells to Alter Signaling and Survival , 2013 .