Medium-sized UAV play an important role in the modern war, In order to ensure its full operational efficiency, UAV, as the High-tech weaponry and equipment, must have a coordinated maintenance and support organization, and provide sufficient maintenance support capability for operational and post-war maintenance. Firstly, this paper discusses the current development of medium UAV maintenance support organizational structure in domestic and foreign, and analyzes the differences between three-level and two-level maintenance and support organization; Then, combining the characteristics of the UAV system and maintenance and support technologies existing to conduct feasibility analysis on the UAV two-level maintenance and support organization for unmanned aerial systems maintenance and support organizations; Finally, this paper give some recommendations about UAV maintenance and support organization structure and integrated support technologies.