Remote homology between Munc13 MUN domain and vesicle tethering complexes.

[1]  D. Devos,et al.  Conservation of Helical Bundle Structure between the Exocyst Subunits , 2009, PloS one.

[2]  M. Munson Tip20p reaches out to Dsl1p to tether membranes , 2009, Nature Structural &Molecular Biology.

[3]  D. Stevens,et al.  The Ca2+-dependent Activator Protein for Secretion CAPS: Do I Dock or do I Prime? , 2009, Molecular Neurobiology.

[4]  M. Yamashita,et al.  The non-neuronal syntaxin SYN-1 regulates defecation behavior and neural activity in C. elegans through interaction with the Munc13-like protein AEX-1. , 2009, Biochemical and biophysical research communications.

[5]  P. Jeffrey,et al.  Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex , 2009, Nature Structural &Molecular Biology.

[6]  J. Rizo,et al.  Synaptic vesicle fusion , 2008, Nature Structural &Molecular Biology.

[7]  U. Matti,et al.  CAPS Facilitates Filling of the Rapidly Releasable Pool of Large Dense-Core Vesicles , 2008, The Journal of Neuroscience.

[8]  F. Varoqueaux,et al.  Munc13-4 Regulates Granule Secretion in Human Neutrophils1 , 2008, The Journal of Immunology.

[9]  U. Heinemann,et al.  Diversity in structure and function of tethering complexes: evidence for different mechanisms in vesicular transport regulation. , 2008, Current protein & peptide science.

[10]  N. Grishin,et al.  PROMALS3D: a tool for multiple protein sequence and structure alignments , 2008, Nucleic acids research.

[11]  A. Brunger,et al.  Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex. , 2008, Structure.

[12]  J. Rizo,et al.  Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes. , 2008, Biochemistry.

[13]  Jian Zhang,et al.  Membrane association and functional regulation of Sec3 by phospholipids and Cdc42 , 2008, The Journal of cell biology.

[14]  Robert D. Finn,et al.  The Pfam protein families database , 2007, Nucleic Acids Res..

[15]  Nils Brose,et al.  CAPS-1 and CAPS-2 Are Essential Synaptic Vesicle Priming Proteins , 2007, Cell.

[16]  Zhaohui Xu,et al.  The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst. , 2007, Journal of molecular biology.

[17]  S. Sugita,et al.  Ca2+-dependent Activator Protein for Secretion 1 Is Critical for Constitutive and Regulated Exocytosis but Not for Loading of Transmitters into Dense Core Vesicles* , 2007, Journal of Biological Chemistry.

[18]  E. Jorgensen,et al.  UNC-31 (CAPS) Is Required for Dense-Core Vesicle But Not Synaptic Vesicle Exocytosis in Caenorhabditis elegans , 2007, The Journal of Neuroscience.

[19]  H. Cai,et al.  Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. , 2007, Developmental cell.

[20]  Mark C. Field,et al.  Control systems for membrane fusion in the ancestral eukaryote; evolution of tethering complexes and SM proteins , 2007, BMC Evolutionary Biology.

[21]  Reinhard Jahn,et al.  SNAREs — engines for membrane fusion , 2006, Nature Reviews Molecular Cell Biology.

[22]  J. Bessereau,et al.  UNC-13 and UNC-10/Rim Localize Synaptic Vesicles to Specific Membrane Domains , 2006, The Journal of Neuroscience.

[23]  D. Brewer,et al.  The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles , 2006, Nature Structural &Molecular Biology.

[24]  Lili Wang,et al.  Schizosaccharomyces pombe Git1 Is a C2-Domain Protein Required for Glucose Activation of Adenylate Cyclase , 2006, Genetics.

[25]  Yui Jin,et al.  Structural basis for myosin V discrimination between distinct cargoes , 2006, The EMBO journal.

[26]  A. West,et al.  Crystal structure of the S.cerevisiae exocyst component Exo70p. , 2005, Journal of molecular biology.

[27]  N. Grishin,et al.  A minimal domain responsible for Munc13 activity , 2005, Nature Structural &Molecular Biology.

[28]  Sunil Q. Mehta,et al.  Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo , 2005, Nature Structural &Molecular Biology.

[29]  Ralf Schneggenburger,et al.  A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? , 2005, The EMBO journal.

[30]  Axel T Brunger,et al.  Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase , 2005, The EMBO journal.

[31]  Johannes Söding,et al.  Protein homology detection by HMM?CHMM comparison , 2005, Bioinform..

[32]  V. A. Klenchin,et al.  CAPS Acts at a Prefusion Step in Dense-Core Vesicle Exocytosis as a PIP2 Binding Protein , 2004, Neuron.

[33]  T. Sūdhof The synaptic vesicle cycle. , 2004, Annual review of neuroscience.

[34]  A. Fischer,et al.  Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3) , 2003, Cell.

[35]  O. Gascuel,et al.  A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. , 2003, Systematic biology.

[36]  Mala Murthy,et al.  Mutations in the Exocyst Component Sec5 Disrupt Neuronal Membrane Traffic, but Neurotransmitter Release Persists , 2003, Neuron.

[37]  S. Munro,et al.  Vesicle tethering complexes in membrane traffic. , 2002, Journal of cell science.

[38]  Christian Rosenmund,et al.  Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[39]  V. A. Klenchin,et al.  Membrane Association Domains in Ca2+-dependent Activator Protein for Secretion Mediate Plasma Membrane and Dense-core Vesicle Binding Required for Ca2+-dependent Exocytosis* , 2002, The Journal of Biological Chemistry.

[40]  Motomichi Doi,et al.  Regulation of Retrograde Signaling at Neuromuscular Junctions by the Novel C2 Domain Protein AEX-1 , 2002, Neuron.

[41]  Jimin Pei,et al.  AL2CO: calculation of positional conservation in a protein sequence alignment , 2001, Bioinform..

[42]  E. Jorgensen,et al.  An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming , 2001, Nature.

[43]  K. Hofmann,et al.  Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform. , 2000, The Biochemical journal.

[44]  E. Jorgensen,et al.  UNC-13 is required for synaptic vesicle fusion in C. elegans , 1999, Nature Neuroscience.

[45]  E. Jorgensen,et al.  One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction , 1999, Nature Neuroscience.

[46]  Thomas C. Südhof,et al.  Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles , 1999, Nature.

[47]  S. Pfeffer Transport-vesicle targeting: tethers before SNAREs , 1999, Nature Cell Biology.

[48]  Y. Nakamura,et al.  Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. , 1998, Biochemical and biophysical research communications.

[49]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[50]  T. Südhof,et al.  Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins (*) , 1995, The Journal of Biological Chemistry.

[51]  A G Murzin,et al.  SCOP: a structural classification of proteins database for the investigation of sequences and structures. , 1995, Journal of molecular biology.

[52]  Reinhard Jahn,et al.  Vesicle fusion from yeast to man , 1994, Nature.

[53]  William R. Taylor,et al.  The rapid generation of mutation data matrices from protein sequences , 1992, Comput. Appl. Biosci..

[54]  N. Saitou,et al.  On the maximum likelihood method in molecular phylogenetics , 1991, Journal of Molecular Evolution.

[55]  Ben M. Webb,et al.  Protein structure modeling with MODELLER. , 2014, Methods in molecular biology.

[56]  P. Novick,et al.  The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif , 2005, Nature Structural &Molecular Biology.

[57]  J. Adachi,et al.  MOLPHY version 2.3 : programs for molecular phylogenetics based on maximum likelihood , 1996 .