Tetrazine ligation for chemical proteomics
暂无分享,去创建一个
[1] J. Elf,et al. Application of Noncanonical Amino Acids for Protein Labeling in a Genomically Recoded Escherichia coli. , 2017, ACS synthetic biology.
[2] P. Kele,et al. Bio‐orthogonal Fluorescent Labelling of Biopolymers through Inverse‐Electron‐Demand Diels–Alder Reactions , 2017, Chembiochem : a European journal of chemical biology.
[3] Michael F. Cuccarese,et al. Quantitating drug-target engagement in single cells in vitro and in vivo. , 2017, Nature chemical biology.
[4] B. Oliveira,et al. Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells , 2016, Angewandte Chemie.
[5] R. Wombacher,et al. Green- to far-red-emitting fluorogenic tetrazine probes – synthetic access and no-wash protein imaging inside living cells† †Electronic supplementary information (ESI) available: Synthetic procedures and spectroscopic data, details of cell experiments and imaging. See DOI: 10.1039/c6sc03879d Click h , 2016, Chemical science.
[6] W. Niu,et al. Fluorogenic protein labeling using a genetically encoded unstrained alkene† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc03635j Click here for additional data file. , 2016, Chemical science.
[7] Peng R. Chen,et al. Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells. , 2016, Angewandte Chemie.
[8] H. Hang,et al. Site-Specific Bioorthogonal Labeling for Fluorescence Imaging of Intracellular Proteins in Living Cells. , 2016, Journal of the American Chemical Society.
[9] I. Choi,et al. A bioorthogonal approach for imaging the binding between Dasatinib and its target proteins inside living cells. , 2016, Chemical communications.
[10] Ralph Weissleder,et al. Imaging approaches to optimize molecular therapies , 2016, Science Translational Medicine.
[11] Haoxing Wu,et al. A Bioorthogonal Near-Infrared Fluorogenic Probe for mRNA Detection. , 2016, Journal of the American Chemical Society.
[12] J. Chin,et al. Tagging and Enriching Proteins Enables Cell-Specific Proteomics , 2016, Cell chemical biology.
[13] Douglas W. Thomson,et al. A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level. , 2016, ACS chemical biology.
[14] Jongmin Park,et al. Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells. , 2016, Chemical communications.
[15] Fang Liu,et al. Diels-Alder Reactivities of Benzene, Pyridine, and Di-, Tri-, and Tetrazines: The Roles of Geometrical Distortions and Orbital Interactions. , 2016, Journal of the American Chemical Society.
[16] Jongmin Park,et al. Investigation of Specific Binding Proteins to Photoaffinity Linkers for Efficient Deconvolution of Target Protein. , 2016, ACS chemical biology.
[17] Jason W. Chin,et al. Selective, rapid and optically switchable regulation of protein function in live mammalian cells. , 2015, Nature chemistry.
[18] J. Chin,et al. Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins , 2015, Journal of the American Chemical Society.
[19] Peng R. Chen,et al. Diels-Alder reaction-triggered bioorthogonal protein decaging in living cells. , 2014, Nature chemical biology.
[20] A. Deiters,et al. Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes. , 2014, Chemical communications.
[21] Steven E. Wheeler,et al. Two Rapid Catalyst-Free Click Reactions for In Vivo Protein Labeling of Genetically Encoded Strained Alkene/Alkyne Functionalities , 2014, Bioconjugate chemistry.
[22] Ligand‐Assisted Dual‐Site Click Labeling of EGFR on Living Cells , 2014, Chembiochem : a European journal of chemical biology.
[23] R. Weissleder,et al. Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. , 2014, Angewandte Chemie.
[24] S. Yao,et al. "Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling. , 2014, Journal of the American Chemical Society.
[25] Carsten Schultz,et al. Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy. , 2014, Angewandte Chemie.
[26] Jennifer A. Prescher,et al. Finding the right (bioorthogonal) chemistry. , 2014, ACS chemical biology.
[27] J. Chin,et al. Bioorthogonal reactions for labeling proteins. , 2014, ACS chemical biology.
[28] H. Janssen,et al. Click to release: instantaneous doxorubicin elimination upon tetrazine ligation. , 2013, Angewandte Chemie.
[29] R. Weissleder,et al. Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET , 2013, PloS one.
[30] Yuguo Zheng,et al. Target identification of biologically active small molecules via in situ methods. , 2013, Current opinion in chemical biology.
[31] R. Weissleder,et al. Bioorthogonal approach to identify unsuspected drug targets in live cells. , 2013, Angewandte Chemie.
[32] R. Weissleder,et al. BODIPY-tetrazine derivatives as superbright bioorthogonal turn-on probes. , 2013, Angewandte Chemie.
[33] C. Slugovc,et al. Inverse electron demand Diels-Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme. , 2013, Chemical Society reviews.
[34] C. Porco,et al. Direct Evidence of a Dinuclear Copper Intermediate in Cu(I)-Catalyzed Azide-Alkyne Cycloadditions , 2013, Science.
[35] P. Clemons,et al. Target identification and mechanism of action in chemical biology and drug discovery. , 2013, Nature chemical biology.
[36] Mark E Bunnage,et al. Target validation using chemical probes. , 2013, Nature chemical biology.
[37] Jongmin Park,et al. From noncovalent to covalent bonds: a paradigm shift in target protein identification. , 2013, Molecular bioSystems.
[38] Herbert Waldmann,et al. Target identification for small bioactive molecules: finding the needle in the haystack. , 2013, Angewandte Chemie.
[39] R. Weissleder,et al. Bioorthogonal imaging of aurora kinase A in live cells. , 2012, Angewandte Chemie.
[40] J. Chin,et al. Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions , 2012, Journal of the American Chemical Society.
[41] Jongmin Park,et al. Discovery and target identification of an antiproliferative agent in live cells using fluorescence difference in two-dimensional gel electrophoresis. , 2012, Angewandte Chemie.
[42] T. Carell,et al. A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction. , 2012, Angewandte Chemie.
[43] Carsten Schultz,et al. Amino acids for Diels-Alder reactions in living cells. , 2012, Angewandte Chemie.
[44] J. Chin,et al. Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction. , 2012, Nature chemistry.
[45] Michael T. Taylor,et al. Genetically encoded tetrazine amino acid directs rapid site-specific in vivo bioorthogonal ligation with trans-cyclooctenes. , 2012, Journal of the American Chemical Society.
[46] Raymond E Moellering,et al. How chemoproteomics can enable drug discovery and development. , 2012, Chemistry & biology.
[47] R. Weissleder,et al. Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. , 2011, Bioconjugate chemistry.
[48] Peng R. Chen,et al. A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. , 2011, Nature chemical biology.
[49] R. Weissleder,et al. Bioorthogonal probes for polo-like kinase 1 imaging and quantification. , 2011, Angewandte Chemie.
[50] M. Debets,et al. Bioconjugation with strained alkenes and alkynes. , 2011, Accounts of chemical research.
[51] R. Weissleder,et al. Biomedical applications of tetrazine cycloadditions. , 2011, Accounts of chemical research.
[52] R. Weissleder,et al. Bioorthogonal Small‐Molecule Ligands for PARP1 Imaging in Living Cells , 2010, Chembiochem : a European journal of chemical biology.
[53] Ian Collins,et al. Probing the Probes: Fitness Factors For Small Molecule Tools , 2010, Chemistry & biology.
[54] R. Weissleder,et al. Bioorthogonal turn-on probes for imaging small molecules inside living cells. , 2010, Angewandte Chemie.
[55] Jason E Hein,et al. Copper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides. , 2010, Chemical Society reviews.
[56] M. Wenk,et al. Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities. , 2010, Journal of the American Chemical Society.
[57] Carolyn R Bertozzi,et al. Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. , 2009, Angewandte Chemie.
[58] G. Superti-Furga,et al. Target profiling of small molecules by chemical proteomics. , 2009, Nature chemical biology.
[59] Roger Y Tsien,et al. Constructing and exploiting the fluorescent protein paintbox (Nobel Lecture). , 2009, Angewandte Chemie.
[60] R. Weissleder,et al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. , 2008, Bioconjugate chemistry.
[61] Joseph M. Fox,et al. Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity. , 2008, Journal of the American Chemical Society.
[62] B. Leslie,et al. Identification of the Cellular Targets of Bioactive Small Organic Molecules Using Affinity Reagents , 2008 .
[63] C. Bertozzi,et al. In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish , 2008, Science.
[64] T. Kodadek,et al. Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. , 2007, Journal of the American Chemical Society.
[65] Carolyn R. Bertozzi,et al. Copper-free click chemistry for dynamic in vivo imaging , 2007, Proceedings of the National Academy of Sciences.
[66] Nurullah Saracoglu,et al. Recent Advances and Applications in 1,2,4,5-Tetrazine Chemistry , 2007 .
[67] M. Uesugi,et al. Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin. , 2007, Journal of the American Chemical Society.
[68] Jennifer A. Prescher,et al. Chemistry in living systems , 2005, Nature chemical biology.
[69] David R Spring,et al. Chemical genetics to chemical genomics: small molecules offer big insights. , 2005, Chemical Society reviews.
[70] Jennifer A. Prescher,et al. A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. , 2004, Journal of the American Chemical Society.
[71] Mark Haw. Holographic data storage: The light fantastic , 2003, Nature.
[72] Anna E Speers,et al. Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition. , 2003, Journal of the American Chemical Society.
[73] S. Gambhir,et al. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. , 2003, Genes & development.
[74] Luke G Green,et al. A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. , 2002, Angewandte Chemie.
[75] Morten Meldal,et al. Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. , 2002, The Journal of organic chemistry.
[76] D. Heldmann,et al. 1,2,4,5‐Tetrazine: Synthesis and Reactivity in [4+2] Cycloadditions , 1998 .
[77] C Humm,et al. The light fantastic. , 1998, Nursing times.
[78] R. Carboni,et al. Reactions of Tetrazines with Unsaturated Compounds. A New Synthesis of Pyridazines , 1959 .