Negative inotropic effects of diadenosine tetraphosphate are mediated by protein kinase C and phosphodiesterases stimulation in the rat heart
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[1] M. Nishida,et al. Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases , 2017, Pharmacology & therapeutics.
[2] K. Guan,et al. PDE2 at the crossway between cAMP and cGMP signalling in the heart. , 2017, Cellular signalling.
[3] A. Kamkin,et al. Diadenosine pentaphosphate affects electrical activity in guinea pig atrium via activation of potassium acetylcholine-dependent inward rectifier , 2017, The Journal of Physiological Sciences.
[4] D. Abramochkin,et al. The role of diadenosine pentaphosphate and nicotinamide adenine dinucleotide (NAD+) as potential nucleotide comediators in the adrenergic regulation of cardiac function , 2017, Neurochemical Journal.
[5] D. Abramochkin,et al. Effects of Nicotinamide Adenine Dinucleotide (NAD+) and Diadenosine Tetraphosphate (Ap4A) on Electrical Activity of Working and Pacemaker Atrial Myocardium in Guinea Pigs , 2016, Bulletin of Experimental Biology and Medicine.
[6] J. Pérez-Schindler,et al. Single inhibition of either PDE3 or PDE4 unmasks β2-adrenoceptor-mediated inotropic and lusitropic effects in the left but not right ventricular myocardium of rat. , 2015, European journal of pharmacology.
[7] L. Durnin,et al. The purinergic neurotransmitter revisited: a single substance or multiple players? , 2014, Pharmacology & therapeutics.
[8] J. Jankowski,et al. Highly sensitive, selective and rapid LC-MS method for simultaneous quantification of diadenosine polyphosphates in human plasma. , 2014, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[9] D. Cooper,et al. AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex. , 2013, The Biochemical journal.
[10] W. Knight,et al. Therapeutic potential of PDE modulation in treating heart disease. , 2013, Future medicinal chemistry.
[11] L. Monge,et al. Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart. , 2011, European journal of pharmacology.
[12] M. Conti,et al. Conserved expression and functions of PDE4 in rodent and human heart , 2010, Basic Research in Cardiology.
[13] Clint L. Miller,et al. Targeting Cyclic Nucleotide Phosphodiesterase in the Heart: Therapeutic Implications , 2010, Journal of cardiovascular translational research.
[14] H. Mischak,et al. Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system , 2009, British journal of pharmacology.
[15] I. Hers,et al. Protein Kinase C-mediated Phosphorylation and Activation of PDE3A Regulate cAMP Levels in Human Platelets* , 2009, Journal of Biological Chemistry.
[16] G. Burnstock,et al. P2 receptors in cardiovascular regulation and disease , 2008, Purinergic Signalling.
[17] Eric A. Barnard,et al. International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy , 2006, Pharmacological Reviews.
[18] G. Reiser,et al. Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors. , 2006, Journal of medicinal chemistry.
[19] H. Schlüter,et al. Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor , 2005, Nature Medicine.
[20] J. Pintor,et al. Interaction between Dinucleotide and Nicotinic Receptors in Individual Cholinergic Terminals , 2004, Journal of Pharmacology and Experimental Therapeutics.
[21] E. Jacobs,et al. P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits. , 2004, American journal of physiology. Heart and circulatory physiology.
[22] H. Schlüter,et al. Identification and Quantification of Diadenosine Polyphosphate Concentrations in Human Plasma , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[23] J. Pintor,et al. Ca2+ Signalling in Brain Synaptosomes Activated by Dinucleotides , 2003, The Journal of Membrane Biology.
[24] Hong Wang,et al. P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197. , 2003, European journal of pharmacology.
[25] S. Buvinic,et al. P2Y1 and P2Y2 receptors are coupled to the NO/cGMP pathway to vasodilate the rat arterial mesenteric bed , 2002, British journal of pharmacology.
[26] M. LeWinter,et al. Activation of PKC decreases myocardial O2 consumption and increases contractile efficiency in rats. , 2001, American journal of physiology. Heart and circulatory physiology.
[27] D. Sheridan,et al. Contribution of nitric oxide and prostanoids to the cardiac electrophysiological and coronary vasomotor effects of diadenosine polyphosphates. , 2001, The Journal of pharmacology and experimental therapeutics.
[28] G. Vassort. Adenosine 5'-triphosphate: a P2-purinergic agonist in the myocardium. , 2001, Physiological reviews.
[29] R. Gerzer,et al. NO-independent regulatory site on soluble guanylate cyclase , 2001, Nature.
[30] Q. Shan,et al. Cardiac and vascular effects of nitric oxide synthase inhibition in lipopolysaccharide-treated rats. , 2000, European journal of pharmacology.
[31] K. Rahn,et al. Diadenosine polyphosphates cause contraction and relaxation in isolated rat resistance arteries. , 2000, The Journal of pharmacology and experimental therapeutics.
[32] J. Pei,et al. The role of phosphodiesterase in mediating the effect of protein kinase C on cyclic AMP accumulation upon kappa-opioid receptor stimulation in the rat heart. , 2000, The Journal of pharmacology and experimental therapeutics.
[33] H. Schlüter,et al. Identification and characterization of diadenosine 5′,5‴‐P1,P2‐diphosphate and diadenosine 5′,5‴‐P1,P3‐triphosphate in human myocardial tissue , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[34] D. Sheridan,et al. The effects of diadenosine polyphosphates on the cardiovascular system. , 1999, Cardiovascular research.
[35] S. Huke,et al. Inotropic effects of diadenosine tetraphosphate (AP4A) in human and animal cardiac preparations. , 1999, The Journal of pharmacology and experimental therapeutics.
[36] J. Pintor,et al. The neurotransmitter role of diadenosine polyphosphates , 1998, FEBS letters.
[37] J. Nishimura,et al. Diadenosine polyphosphates directly relax porcine coronary arterial smooth muscle. , 1997, The Journal of pharmacology and experimental therapeutics.
[38] E. Barnard,et al. Molecular biology of P2Y purinoceptors: expression in rat heart. , 1996, Journal of autonomic pharmacology.
[39] G. Burnstock,et al. The activation of P1‐ and P2‐purinoceptors in the guinea‐pig left atrium by diadenosine polyphosphates , 1996, British journal of pharmacology.
[40] W. Paulus,et al. Myocardial contractile response to nitric oxide and cGMP. , 1996, Circulation.
[41] H. Schlüter,et al. Diadenosine phosphates and the physiological control of blood pressure , 1994, Nature.
[42] M. Miras-Portugal,et al. Diadenosine polyphosphate (ApxA) as new neurotransmitters , 1993 .
[43] R. Busse,et al. Potent effects of AP3A and AP4A on coronary resistance and autacoid release of intact rabbit hearts. , 1991, The American journal of physiology.
[44] G. Isenberg,et al. Calcium tolerant ventricular myocytes prepared by preincubation in a “KB medium” , 1982, Pflügers Archiv.
[45] H. Nechushtan,et al. Amino-acyl tRNA synthetases generate dinucleotide polyphosphates as second messengers: functional implications. , 2014, Topics in current chemistry.
[46] G. Reiser,et al. Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor. , 2008, The Biochemical journal.
[47] G. Reiser,et al. Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor. , 2008, The Biochemical journal.
[48] H. Schlüter,et al. Inotropic effects of diadenosine tetraphosphate in isolated canine cardiac preparations. , 1999, Journal of cardiovascular pharmacology.
[49] W. Thompson. Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function. , 1991, Pharmacology & therapeutics.