Mechanisms of myofibroblast activity and phenotypic modulation.

[1]  J. Massagué,et al.  Regulation of cell adhesion receptors by transforming growth factor-beta. Regulation of vitronectin receptor and LFA-1. , 1989, The Journal of biological chemistry.

[2]  O. Petersen,et al.  A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts , 1996, The Journal of cell biology.

[3]  V. Koteliansky,et al.  Expression of extra domain A fibronectin sequence in vascular smooth muscle cells is phenotype dependent , 1989, The Journal of cell biology.

[4]  J. Murphy-Ullrich,et al.  Thrombospondin causes activation of latent transforming growth factor- beta secreted by endothelial cells by a novel mechanism [published erratum appears in J Cell Biol 1993 Sep;122(5):following 1143] , 1993, The Journal of cell biology.

[5]  A. Desmoulière,et al.  Heparin induces alpha-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts. , 1992, Laboratory investigation; a journal of technical methods and pathology.

[6]  M. Rekhter,et al.  Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. , 1994, The American journal of pathology.

[7]  X. Causse,et al.  Interferon‐α2b therapy reduces liver fibrosis in chronic non‐A, non‐B hepatitis: A quantitative histological evaluation , 1993, Hepatology.

[8]  Sadao Kimura,et al.  A novel potent vasoconstrictor peptide produced by vascular endothelial cells , 1988, Nature.

[9]  D. Baker,et al.  Fibronectin Type III Repeats Mediate RGD-independent Adhesion and Signaling through Activated β1 Integrins* , 1997, The Journal of Biological Chemistry.

[10]  L. Wakefield,et al.  Release and activation of platelet latent TGF–β in blood clots during dissolution with plasmin , 1995, Nature Medicine.

[11]  B. Hirschel,et al.  GRANULATION TISSUE AS A CONTRACTILE ORGAN: A STUDY OF STRUCTURE AND FUNCTION , 1972 .

[12]  A. Vaheri,et al.  Sequential appearance of fibronectin and collagen in experimental granulation tissue. , 1980, Laboratory investigation; a journal of technical methods and pathology.

[13]  H. Antoniades,et al.  Injury induces in vivo expression of platelet-derived growth factor (PDGF) and PDGF receptor mRNAs in skin epithelial cells and PDGF mRNA in connective tissue fibroblasts. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Albert K. Harris,et al.  Fibroblast traction as a mechanism for collagen morphogenesis , 1981, Nature.

[15]  M. Majesky,et al.  Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta , 1990, The Journal of cell biology.

[16]  G. Gabbiani,et al.  Rat alveolar myofibroblasts acquire alpha-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis. , 1993, The American journal of pathology.

[17]  E. Ruoslahti,et al.  Transforming growth factor-beta in disease: the dark side of tissue repair. , 1992, The Journal of clinical investigation.

[18]  G. Tuszynski,et al.  Matrix-bound thrombospondin promotes angiogenesis in vitro , 1994, The Journal of cell biology.

[19]  J. Moyano,et al.  Fibronectin Type III5 Repeat Contains a Novel Cell Adhesion Sequence, KLDAPT, Which Binds Activated α4β1 and α4β7 Integrins* , 1997, The Journal of Biological Chemistry.

[20]  P. Lindahl,et al.  Not all myofibroblasts are alike: revisiting the role of PDGF‐A and PDGF‐B using PDGF‐targeted mice , 1998, Current opinion in nephrology and hypertension.

[21]  R. Pascal,et al.  The colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. 3. Replication and differentiation in human hyperplastic and adenomatous polyps. , 1971, Gastroenterology.

[22]  G. Gabbiani,et al.  Early granulocyte-macrophage colony-stimulating factor expression by alveolar inflammatory cells during bleomycin-induced rat lung fibrosis. , 1998, Laboratory investigation; a journal of technical methods and pathology.

[23]  G. Gabbiani Some historical and philosophical reflections on the myofibroblast concept. , 1999, Current topics in pathology. Ergebnisse der Pathologie.

[24]  G. Proetzel,et al.  Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease , 1992, Nature.

[25]  E Ruoslahti,et al.  RGD and other recognition sequences for integrins. , 1996, Annual review of cell and developmental biology.

[26]  Harold E. Dvorak,et al.  Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat , 1989, The Journal of cell biology.

[27]  D. J. Miletich,et al.  Progesterone Potentiation of Bupivacaine Arrhythmogenicity in Pentobarbital‐Anesthetized Rats and Beating Rat Heart Cell Cultures , 1992, Journal of cardiovascular pharmacology.

[28]  A. Giannetti,et al.  Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing , 1995, The Journal of cell biology.

[29]  N. Kaminski,et al.  The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. , 1999, Cell.

[30]  Z. Werb,et al.  ECM signalling: orchestrating cell behaviour and misbehaviour. , 1998, Trends in cell biology.

[31]  M. Sporn,et al.  Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex , 1990, Molecular and cellular biology.

[32]  Paul Martin,et al.  Wound Healing--Aiming for Perfect Skin Regeneration , 1997, Science.

[33]  I. Singer The fibronexus: a transmembrane association of fibronectin-containing fibers and bundles of 5 nm microfilaments in hamster and human fibroblasts , 1979, Cell.

[34]  D. Rifkin,et al.  Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1 , 1998 .

[35]  W. Schürch,et al.  Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. , 1990, Laboratory investigation; a journal of technical methods and pathology.

[36]  G. Mariani,et al.  Tumor targeting potential of the monoclonal antibody BC‐1 against oncofetal fibronectin in nude mice bearing human tumor implants , 1997, Cancer.

[37]  A. Desmoulière,et al.  GM-CSF-induced granulation tissue formation: relationships between macrophage and myofibroblast accumulation , 1993, Virchows Archiv. B, Cell pathology including molecular pathology.

[38]  A. Desmoulière,et al.  α-Smooth muscle actin is expressed in a subpopulation of cultured and cloned fibroblasts and is modulated by γ-interferon☆ , 1992 .

[39]  R. Pascal,et al.  Colonic pericryptal fibroblast sheath: replication, migration, and cytodifferentiation of a mesenchymal cell system in adult tissue. II. Fine structural aspects of normal rabbit and human colon. , 1968, Gastroenterology.

[40]  C. Betsholtz,et al.  PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis , 1996, Cell.

[41]  Arne N. Akbar,et al.  RGD peptides induce apoptosis by direct caspase-3 activation , 1999, Nature.

[42]  D. Rockey,et al.  Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing. , 1996, The Journal of clinical investigation.

[43]  W. Schürch,et al.  Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. , 1989, Laboratory investigation; a journal of technical methods and pathology.

[44]  M. Odenthal,et al.  Synthesis of cellular fibronectin by rat liver fat-storing (Ito) cells: regulation by cytokines. , 1992, Gastroenterology.

[45]  P. Bornstein,et al.  Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Mustafa,et al.  Endothelin association with the cultured rat Kupffer cell: Characterization and regulation , 1995, Hepatology.

[47]  F. Bühler,et al.  Effects of Endothelin‐1 on Vascular Smooth Muscle Cell Phenotypic Differentiation , 1992, Journal of cardiovascular pharmacology.

[48]  R. Muschel,et al.  Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on the G2 delay. , 1996, Oncogene.

[49]  Sumio Watanabe,et al.  Immunocytochemical Detection of Desmin in Fat‐Storing Cells (Ito Cells) , 1984, Hepatology.

[50]  S. Frisch,et al.  Disruption of epithelial cell-matrix interactions induces apoptosis , 1994, The Journal of cell biology.

[51]  E. Chambaz,et al.  Thrombospondins selectively activate one of the two latent forms of transforming growth factor-beta present in adrenocortical cell-conditioned medium. , 1995, Endocrinology.

[52]  K. Cutroneo,et al.  Auto-induction of transforming growth factor-beta in human lung fibroblasts. , 1993, American journal of respiratory cell and molecular biology.

[53]  A. Desmoulière,et al.  Effect of gamma-interferon on the clinical and biologic evolution of hypertrophic scars and Dupuytren's disease: an open pilot study. , 1994, Plastic and reconstructive surgery.

[54]  K. Miyazono,et al.  Transforming growth factor-beta: latent forms, binding proteins and receptors. , 1993, Growth factors.

[55]  W. Jiménez,et al.  Endothelin 1 does not play a major role in the homeostasis of arterial pressure in cirrhotic rats with ascites. , 1995, Gastroenterology.

[56]  B R Johansson,et al.  Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. , 1997, Science.

[57]  D. Rockey,et al.  Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis , 1994, The Journal of cell biology.

[58]  T. Pawson,et al.  The discoidin domain receptor tyrosine kinases are activated by collagen. , 1997, Molecular cell.

[59]  J. Marx DNA repair defect tied to mutated TGF-beta receptor gene. , 1995, Science.

[60]  L. Rubbia‐Brandt,et al.  Locally applied GM-CSF induces the accumulation of α-smooth muscle act in containing myofibroblasts , 1991, Virchows Archiv. B, Cell pathology including molecular pathology.

[61]  K. Syrigos,et al.  A pilot pharmacokinetic and immunoscintigraphic study with the technetium‐99m‐labeled monoclonal antibody BC‐1 directed against oncofetal fibronectin in patients with brain tumors , 1997, Cancer.

[62]  C. Betsholtz,et al.  Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. , 1997, Development.

[63]  M. Sporn,et al.  Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[64]  R. Hammer,et al.  Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons , 1994, Cell.

[65]  G. Gabbiani,et al.  Alpha smooth muscle actin (α-SM actin) in normal human ovaries, in ovarian stromal hyperplasia and in ovarian neoplasms , 1989, Virchows Archiv. B, Cell pathology including molecular pathology.

[66]  D. Danielpour,et al.  Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat. , 1993, The Journal of clinical investigation.

[67]  J. Massagué,et al.  Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. , 1986, The Journal of biological chemistry.

[68]  Gary R. Grotendorst,et al.  Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. , 1993, Molecular biology of the cell.

[69]  F. Giancotti,et al.  Integrin signaling: specificity and control of cell survival and cell cycle progression. , 1997, Current opinion in cell biology.

[70]  G. Gabbiani,et al.  Rat fibroblasts cultured from various organs exhibit differences in alpha-smooth muscle actin expression, cytoskeletal pattern, and adhesive structure organization. , 1998, Experimental cell research.

[71]  D. Ingber Tensegrity: the architectural basis of cellular mechanotransduction. , 1997, Annual review of physiology.

[72]  A. Desmoulière,et al.  Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. , 1995, The American journal of pathology.

[73]  M. Klagsbrun,et al.  Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor , 1985, The Journal of cell biology.

[74]  G. Yancopoulos,et al.  An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. , 1997, Molecular cell.

[75]  Kohei Miyazono,et al.  TGF-β signalling from cell membrane to nucleus through SMAD proteins , 1997, Nature.

[76]  A. Desmoulière,et al.  Modulation of fibroblastic cytoskeletal features during pathological situations: the role of extracellular matrix and cytokines. , 1994, Cell motility and the cytoskeleton.

[77]  O. Petersen,et al.  Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia. , 1993, Laboratory investigation; a journal of technical methods and pathology.

[78]  J. MacLeod,et al.  Fibronectin mRNA Splice Variant in Articular Cartilage Lacks Bases Encoding the V, III-15, and I-10 Protein Segments* , 1996, The Journal of Biological Chemistry.

[79]  P. Sime,et al.  Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation. , 1997, The American journal of pathology.

[80]  S. Friedman,et al.  Hepatic lipocytes: a major target for endothelin-1. , 1995, Journal of hepatology.

[81]  P. McKeown-Longo,et al.  Activation of Distinct α5β1-mediated Signaling Pathways by Fibronectin's Cell Adhesion and Matrix Assembly Domains , 1998, The Journal of cell biology.

[82]  C. Chaponnier,et al.  Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung. , 1992, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[83]  B Swolin,et al.  Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. , 1994, Genes & development.

[84]  R. Clark,et al.  In vivo co-distribution of fibronectin and actin fibers in granulation tissue: immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface , 1984, The Journal of cell biology.

[85]  W. Couser,et al.  Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo. , 1995, Kidney international.

[86]  R. Cuthbertson,et al.  Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage , 1987, Cell.

[87]  Giulio Gabbiani,et al.  Modulation of α‐smooth muscle actin expression in fibroblasts by transforming growth factor‐β isoforms: an in vivo and in vitro study , 1996, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[88]  D. Fisher,et al.  Loss of Matrix Adhesion Triggers Rapid Transformation-Selective Apoptosis in Fibroblasts , 1997, The Journal of cell biology.

[89]  R. Braun,et al.  Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis. , 1997, Biochemical pharmacology.

[90]  S. Schultz-Cherry,et al.  Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system. , 1994, The Journal of biological chemistry.

[91]  J. Massagué,et al.  Control of junB and extracellular matrix protein expression by transforming growth factor-beta 1 is independent of simian virus 40 T antigen-sensitive growth-sensitive growth-inhibitory events , 1991, Molecular and cellular biology.

[92]  Y. Kaneda,et al.  Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney , 1996, Nature Medicine.

[93]  V. Everts,et al.  Fine structure of fibroblasts in the periodontal ligament of the rat incisor and their possible role in tooth eruption. , 1974, Archives of oral biology.

[94]  R. S. Bressler Myoid cells in the capsule of the adrenal gland and in monolayers derived from cultured adrenal capsules , 1973, The Anatomical record.

[95]  P. Basset,et al.  Expression of Matrix Metalloproteinases during Rat Skin Wound Healing: Evidence that Membrane Type-1 Matrix Metalloproteinase Is a Stromal Activator of Pro-Gelatinase A , 1997, The Journal of cell biology.

[96]  P. Janmey,et al.  The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo , 1995, The Journal of cell biology.

[97]  D. Kletsas,et al.  Autocrine growth regulation in fetal and adult human fibroblasts. , 1997, Biochemical and biophysical research communications.

[98]  C. Pesce,et al.  The fibronectin gene as a model for splicing and transcription studies , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[99]  H. Dvorak,et al.  Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing. , 1993, The American journal of pathology.

[100]  M. Centrella,et al.  Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis. , 1996, The Journal of clinical investigation.

[101]  Stephen S. Sternberg,et al.  Histology for Pathologists , 1992, Annals of Internal Medicine.

[102]  E Ruoslahti,et al.  Integrins and anoikis. , 1997, Current opinion in cell biology.

[103]  J. Moyano,et al.  Cooperative role for activated alpha4 beta1 integrin and chondroitin sulfate proteoglycans in cell adhesion to the heparin III domain of fibronectin. Identification of a novel heparin and cell binding sequence in repeat III5. , 1999, The Journal of biological chemistry.

[104]  A. Brunner,et al.  Type 1 transforming growth factor beta: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells , 1987, Molecular and cellular biology.

[105]  L. Trusolino,et al.  Growth Factor–dependent Activation of αvβ3 Integrin in Normal Epithelial Cells: Implications for Tumor Invasion , 1998, The Journal of cell biology.

[106]  M. Sporn,et al.  Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation , 1989, The Journal of experimental medicine.

[107]  W. Couser,et al.  Thrombospondin 1 precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease in the rat. , 1998, Kidney international.

[108]  K. Sekiguchi,et al.  Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment , 1997, The Journal of cell biology.

[109]  A. Gown,et al.  The cytoskeleton of stromal cells from human bone marrow cultures resembles that of cultured smooth muscle cells. , 1990, Experimental hematology.

[110]  M. Schwartz Integrins, Oncogenes, and Anchorage Independence , 1997, The Journal of cell biology.

[111]  J. Slavin REVIEW ARTICLE. THE ROLE OF CYTOKINES IN WOUND HEALING , 1996 .

[112]  Dario Neri,et al.  Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform , 1997, Nature Biotechnology.

[113]  O. Kocher,et al.  Alternative splicing of endothelial cell fibronectin mRNA in the IIICS region. Functional significance. , 1990, The American journal of pathology.

[114]  M. Sporn,et al.  Transforming growth factor-beta: recent progress and new challenges , 1992, The Journal of cell biology.

[115]  M. Moutet,et al.  Expression of fibronectin ED-A+ and ED-B+ isoforms by human and experimental colorectal cancer. Contribution of cancer cells and tumor-associated myofibroblasts. , 1996, The American journal of pathology.

[116]  L. Culp,et al.  Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA) and its neighboring type III repeats: oncogene-dependent regulation. , 1994, Experimental cell research.

[117]  A. Geinoz,et al.  The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1 , 1998, Journal of Cell Biology.

[118]  L. Zardi,et al.  Transforming growth factor beta regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts. , 1988, FEBS letters.

[119]  L. Zardi,et al.  Transforming growth factor‐β regulates the splicing pattern of fibronectin messenger RNA precursor , 1990, FEBS letters.

[120]  G. Gabbiani,et al.  Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. , 1990, Laboratory investigation; a journal of technical methods and pathology.

[121]  Kenneth M. Yamada,et al.  Integrin transmembrane signaling and cytoskeletal control. , 1995, Current opinion in cell biology.

[122]  Richard O. Hynes,et al.  Integrins: Versatility, modulation, and signaling in cell adhesion , 1992, Cell.

[123]  M. Sheetz,et al.  Forces on adhesive contacts affect cell function. , 1998, Current opinion in cell biology.

[124]  S. Schultz-Cherry,et al.  Transforming growth factor-beta complexes with thrombospondin. , 1992, Molecular biology of the cell.

[125]  Z. Werb ECM and Cell Surface Proteolysis: Regulating Cellular Ecology , 1997, Cell.

[126]  M. Bissell,et al.  Extracellular matrix signaling: integration of form and function in normal and malignant cells. , 1998, Current opinion in cell biology.

[127]  J. Fluck,et al.  Normal human primary fibroblasts undergo apoptosis in three-dimensional contractile collagen gels. , 1998, The Journal of investigative dermatology.

[128]  D. Dhumeaux,et al.  Interferon alfa and gamma inhibit proliferation and collagen synthesis of human ito cells in culture , 1995, Hepatology.

[129]  A. Desmoulière,et al.  Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts , 1993, The Journal of cell biology.

[130]  Frederick Grinnell,et al.  Fibroblasts, myofibroblasts, and wound contraction , 1994, The Journal of cell biology.

[131]  M. Sporn,et al.  Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[132]  B. Hirschel,et al.  Contraction of Granulation Tissue in vitro: Similarity to Smooth Muscle , 1971, Science.

[133]  W. Border,et al.  Transforming Growth Factor β in Tissue Fibrosis , 1994 .

[134]  S. Glasser,et al.  Intermediate filament protein as a marker of uterine stromal cell decidualization. , 1986, Biology of reproduction.

[135]  G. Gabbiani,et al.  Characterization of stromal cells with myoid features in lymph nodes and spleen in normal and pathologic conditions. , 1987, The American journal of pathology.

[136]  J. Brugge,et al.  Integrins and signal transduction pathways: the road taken. , 1995, Science.

[137]  R. Plevin,et al.  Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts. , 1990, The Biochemical journal.

[138]  K. Badr,et al.  Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. , 1992, The New England journal of medicine.

[139]  Philippe Soriano,et al.  Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. , 1994, Genes & development.

[140]  R. Assoian,et al.  Anchorage-dependent Cell Cycle Progression , 1997, The Journal of cell biology.

[141]  R. Hynes,et al.  Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo , 1998, Cell.