Histone deacetylase function in CD4+ T cells

[1]  Clare L. Garcin,et al.  Microtubules in cell migration , 2019, Essays in biochemistry.

[2]  C. Olsen,et al.  Histone Deacetylase 11 is an ε-N-Myristoyllysine Hydrolase , 2017, bioRxiv.

[3]  E. Verdin,et al.  Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells , 2018, eLife.

[4]  D. Margolis,et al.  HIV latency is reversed by ACSS2-driven histone crotonylation , 2018, The Journal of clinical investigation.

[5]  Zsofia Kutil,et al.  Histone Deacetylase 11 Is a Fatty-Acid Deacylase. , 2018, ACS chemical biology.

[6]  M. Veldhoen,et al.  Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases , 2018, Nature Communications.

[7]  N. Krogan,et al.  Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1 , 2018, The Journal of experimental medicine.

[8]  C. Olsen,et al.  Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio. , 2017, Biochimica et biophysica acta. Bioenergetics.

[9]  B. Prabhakar,et al.  The epigenetic drug Trichostatin A ameliorates experimental autoimmune encephalomyelitis via T cell tolerance induction and impaired influx of T cells into the spinal cord , 2017, Neurobiology of Disease.

[10]  J. Zikherman,et al.  Tonic Signals: Why Do Lymphocytes Bother? , 2017, Trends in immunology.

[11]  A. McKenzie,et al.  TH2 cell development and function , 2017, Nature Reviews Immunology.

[12]  Maria Colomé-Tatché,et al.  Histone propionylation is a mark of active chromatin , 2017, Nature Structural & Molecular Biology.

[13]  E. Seto,et al.  Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function , 2017, Scientific Reports.

[14]  F. Pan,et al.  The regulation of immune tolerance by FOXP3 , 2017, Nature Reviews Immunology.

[15]  Puspa Thapa,et al.  Histone deacetylase 3 is required for iNKT cell development , 2017, Scientific Reports.

[16]  D. Woods,et al.  T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model. , 2017, Blood.

[17]  J. Auwerx,et al.  Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections , 2017, Scientific Reports.

[18]  M. Kwiatkowski,et al.  Targeting transcription factor lysine acetylation in inflammatory airway diseases. , 2017, Epigenomics.

[19]  S. Horwitz,et al.  Targeting histone deacetylases in T-cell lymphoma , 2017, Leukemia & lymphoma.

[20]  B. Stockinger,et al.  The dichotomous nature of T helper 17 cells , 2017, Nature Reviews Immunology.

[21]  E. Verdin,et al.  Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. , 2017, Cell reports.

[22]  D. Christianson,et al.  Histone deacetylase 10 structure and molecular function as a polyamine deacetylase , 2017, Nature Communications.

[23]  Jianjun Yu,et al.  Class I histone deacetylases are major histone decrotonylases: evidence for critical and broad function of histone crotonylation in transcription , 2017, Cell Research.

[24]  R. Boidot,et al.  Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation. , 2017, Cell reports.

[25]  P. Eyers,et al.  Bio-Zombie: the rise of pseudoenzymes in biology. , 2017, Biochemical Society transactions.

[26]  J. Schwabe,et al.  Targeting Class I Histone Deacetylases in a "Complex" Environment. , 2017, Trends in pharmacological sciences.

[27]  Aleksandra A. Kolodziejczyk,et al.  Dysbiosis and the immune system , 2017, Nature Reviews Immunology.

[28]  Min Liu,et al.  HDAC6 regulates IL-17 expression in T lymphocytes: implications for HDAC6-targeted therapies , 2017, Theranostics.

[29]  Takashi Saito,et al.  CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function , 2017, Front. Immunol..

[30]  Stephen L. Brown,et al.  HDAC4 is expressed on multiple T cell lineages but dispensable for their development and function , 2017, Oncotarget.

[31]  S. Kent,et al.  Cytotoxic CD4 T Cells—Friend or Foe during Viral Infection? , 2017, Front. Immunol..

[32]  P. Filippakopoulos,et al.  Functions of bromodomain-containing proteins and their roles in homeostasis and cancer , 2017, Nature Reviews Molecular Cell Biology.

[33]  Di Zhang,et al.  Metabolic regulation of gene expression through histone acylations , 2016, Nature Reviews Molecular Cell Biology.

[34]  R. Ramasamy,et al.  Mechanisms of transcription factor acetylation and consequences in hearts. , 2016, Biochimica et biophysica acta.

[35]  T. Arnesen,et al.  The world of protein acetylation. , 2016, Biochimica et biophysica acta.

[36]  B. Honig,et al.  Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode , 2016, Nature.

[37]  B. Honig,et al.  The p53-SET Interplays Reveal A New Mode of Acetylation-dependent Regulation , 2016, Nature.

[38]  J. Hakkola,et al.  Who watches the watchmen? Regulation of the expression and activity of sirtuins , 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[39]  M. Constans,et al.  HDAC3 Is Required for the Downregulation of RORγt during Thymocyte Positive Selection , 2016, The Journal of Immunology.

[40]  Yun Lu,et al.  Histone Deacetylase SIRT1 Negatively Regulates the Differentiation of Interleukin-9-Producing CD4(+) T Cells. , 2016, Immunity.

[41]  W. Garrett,et al.  Gut microbiota, metabolites and host immunity , 2016, Nature Reviews Immunology.

[42]  F. Hansen,et al.  HDAC5 controls the functions of Foxp3+ T‐regulatory and CD8+ T cells , 2016, International journal of cancer.

[43]  C. Brightling,et al.  Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma. , 2016, The Journal of allergy and clinical immunology.

[44]  Haipeng Guan,et al.  Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. , 2016, Molecular cell.

[45]  R. Roeder,et al.  Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters , 2016, Molecular cell.

[46]  Chen Zeng,et al.  Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity , 2016, Nature Immunology.

[47]  F. Sánchez‐Madrid,et al.  HDAC6 regulates the dynamics of lytic granules in cytotoxic T lymphocytes , 2016, Journal of Cell Science.

[48]  J. Cappelleri,et al.  Patient Preferences Regarding Rheumatoid Arthritis Therapies: A Conjoint Analysis. , 2016, American health & drug benefits.

[49]  J. Bluestone,et al.  Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease , 2016, Nature Reviews Immunology.

[50]  M. Dimopoulos,et al.  The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies. , 2016, Cancer treatment reviews.

[51]  J. Nie,et al.  Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1 , 2015, Scientific Reports.

[52]  S. Hugues,et al.  Th17 Cell Plasticity and Functions in Cancer Immunity , 2015, BioMed research international.

[53]  Y. Ahn,et al.  Role of transcription factor acetylation in the regulation of metabolic homeostasis , 2015, Protein & Cell.

[54]  S. Hiebert,et al.  Histone Deacetylase 3 Is Required for Efficient T Cell Development , 2015, Molecular and Cellular Biology.

[55]  M. Constans,et al.  Histone Deacetylase 3 Is Required for T Cell Maturation , 2015, The Journal of Immunology.

[56]  J. Schwabe,et al.  Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex , 2015, The Journal of Biological Chemistry.

[57]  Michael J. T. Stubbington,et al.  The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding , 2015, PLoS genetics.

[58]  V. Kuchroo,et al.  Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity. , 2015, The Journal of clinical investigation.

[59]  B. Gibson,et al.  SIRT1 deacetylates RORγt and enhances Th17 cell generation , 2015, The Journal of experimental medicine.

[60]  Birgit Schilling,et al.  SIRT1 deacetylates RORγt and enhances Th17 cell generation , 2015, The Journal of experimental medicine.

[61]  Leila Haery,et al.  Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy , 2015, Genes & cancer.

[62]  M. Kaplan,et al.  The development and in vivo function of T helper 9 cells , 2015, Nature Reviews Immunology.

[63]  M. Greene,et al.  FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. , 2015, The Journal of clinical investigation.

[64]  D. Wallace,et al.  Essential role of mitochondrial energy metabolism in Foxp3+ T‐regulatory cell function and allograft survival , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[65]  Fan-Chi Hsu,et al.  Immature Recent Thymic Emigrants Are Eliminated by Complement , 2014, The Journal of Immunology.

[66]  B. Ludewig,et al.  HDAC1 Controls CD8+ T Cell Homeostasis and Antiviral Response , 2014, PloS one.

[67]  R. Johnstone,et al.  Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders , 2014, Nature Reviews Drug Discovery.

[68]  P. Coffer,et al.  Post-translational modification networks regulating FOXP3 function. , 2014, Trends in immunology.

[69]  Chunaram Choudhary,et al.  The growing landscape of lysine acetylation links metabolism and cell signalling , 2014, Nature Reviews Molecular Cell Biology.

[70]  N. Mosammaparast,et al.  Crosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repair. , 2014, Trends in cell biology.

[71]  Ming-Ming Zhou,et al.  Writers and readers of histone acetylation: structure, mechanism, and inhibition. , 2014, Cold Spring Harbor perspectives in biology.

[72]  Hening Lin,et al.  Sirtuin inhibitors as anticancer agents. , 2014, Future medicinal chemistry.

[73]  E. Seto,et al.  Erasers of histone acetylation: the histone deacetylase enzymes. , 2014, Cold Spring Harbor perspectives in biology.

[74]  K. Bennett,et al.  CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2 , 2014, Nature Immunology.

[75]  H. Lassmann,et al.  A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog , 2014, Development.

[76]  R. Johnstone,et al.  New and emerging HDAC inhibitors for cancer treatment. , 2014, The Journal of clinical investigation.

[77]  Kyoung-Jae Won,et al.  Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor. , 2013, Molecular cell.

[78]  H. Cheroutre,et al.  CD4 CTL: living up to the challenge. , 2013, Seminars in immunology.

[79]  P. Matthias,et al.  Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis , 2013, The EMBO journal.

[80]  A. Rudensky,et al.  Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation , 2013, Nature.

[81]  M. Tomita,et al.  Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells , 2013, Nature.

[82]  Q. Xia,et al.  The role of acetylation in TLR4‐mediated innate immune responses , 2013, Immunology and cell biology.

[83]  C. Seiser,et al.  Transcription and beyond: the role of mammalian class I lysine deacetylases , 2013, Chromosoma.

[84]  S. Étienne-Manneville Microtubules in cell migration. , 2013, Annual review of cell and developmental biology.

[85]  W. Garrett,et al.  The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis , 2013, Science.

[86]  N. Kelleher,et al.  Measurement of acetylation turnover at distinct lysines in human histones identifies long-lived acetylation sites , 2013, Nature Communications.

[87]  L. Tsai,et al.  SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons , 2013, Nature Neuroscience.

[88]  Amanda J. Guise,et al.  The functional interactome landscape of the human histone deacetylase family , 2013, Molecular systems biology.

[89]  S. Cowley,et al.  The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts. , 2013, Biochemical Society transactions.

[90]  E. Verdin,et al.  Reactivation of latent HIV by histone deacetylase inhibitors. , 2013, Trends in microbiology.

[91]  Valeria Manríquez,et al.  Trichostatin A Promotes the Generation and Suppressive Functions of Regulatory T Cells , 2013, Clinical & developmental immunology.

[92]  P. Fink The biology of recent thymic emigrants. , 2013, Annual review of immunology.

[93]  L. Wessels,et al.  Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function. , 2013, Blood.

[94]  S. Desiderio,et al.  The transcriptional repressor NKAP is required for the development of iNKT cells , 2013, Nature Communications.

[95]  J. Hao,et al.  Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis , 2013, Experimental Neurology.

[96]  O. Dovey,et al.  Histone deacetylase (HDAC) 1 and 2 are essential for normal T cell development and genomic stability in mice , 2013, Clinical Epigenetics.

[97]  R. Shaw,et al.  Metabolic reprogramming by class I and II histone deacetylases , 2013, Trends in Endocrinology & Metabolism.

[98]  K. Honda,et al.  Transcriptional Reprogramming of Mature CD4+ T helper Cells generates distinct MHC class II-restricted Cytotoxic T Lymphocytes , 2013, Nature Immunology.

[99]  Aneta Rogoz,et al.  Mutual expression of Runx3 and ThPOK regulates intestinal CD4+ T cell immunity , 2012, Nature Immunology.

[100]  D. Mottet,et al.  Nuclear export of histone deacetylase 7 during thymic selection is required for immune self‐tolerance , 2012, The EMBO journal.

[101]  Dorte B. Bekker-Jensen,et al.  Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns , 2012, Cell reports.

[102]  Xiaolong Liu,et al.  Epigenetic Silencing of Cd8 Genes by ThPOK-Mediated Deacetylation during CD4 T Cell Differentiation , 2012, The Journal of Immunology.

[103]  U. Beier,et al.  Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3+ Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms , 2012, Science Signaling.

[104]  I. Cristea,et al.  Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16 , 2012, Proceedings of the National Academy of Sciences.

[105]  A. Macpherson,et al.  Interactions Between the Microbiota and the Immune System , 2012, Science.

[106]  William Arbuthnot Sir Lane,et al.  SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60 , 2012, Molecular and Cellular Biology.

[107]  J. O’Shea,et al.  Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. , 2012, Annual review of immunology.

[108]  A. Rudensky,et al.  Regulatory T cells: mechanisms of differentiation and function. , 2012, Annual review of immunology.

[109]  E. Verdin,et al.  Three Novel Acetylation Sites in the Foxp3 Transcription Factor Regulate the Suppressive Activity of Regulatory T Cells , 2012, The Journal of Immunology.

[110]  U. Beier,et al.  Histone/protein deacetylases and T-cell immune responses. , 2012, Blood.

[111]  Johan Auwerx,et al.  Sirtuins as regulators of metabolism and healthspan , 2012, Nature Reviews Molecular Cell Biology.

[112]  P. Matthias,et al.  Multiple roles of class I HDACs in proliferation, differentiation, and development , 2012, Cellular and Molecular Life Sciences.

[113]  Johan Auwerx,et al.  Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase , 2011, Science.

[114]  Zhike Lu,et al.  Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification , 2011, Cell.

[115]  B. Garcia,et al.  Histone Deacetylase 9 Deficiency Protects against Effector T Cell-mediated Systemic Autoimmunity* , 2011, The Journal of Biological Chemistry.

[116]  C. Dinarello,et al.  Histone Deacetylase Inhibitors for Treating a Spectrum of Diseases Not Related to Cancer , 2011, Molecular medicine.

[117]  E. Lam,et al.  Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1 , 2011, PloS one.

[118]  D. Mottet,et al.  Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes , 2011, The Journal of Immunology.

[119]  Kyle V. Butler,et al.  Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells , 2011, Molecular and Cellular Biology.

[120]  C. Dinarello,et al.  Histone Deacetylase Inhibitors for Purging HIV-1 from the Latent Reservoir , 2011, Molecular medicine.

[121]  P. Grandi,et al.  Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes , 2011, Nature Biotechnology.

[122]  U. Beier,et al.  Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function and Prolongs Allograft Survival , 2011, Molecular and Cellular Biology.

[123]  S. Chiocca,et al.  Regulating the Regulators: The Post-Translational Code of Class I HDAC1 and HDAC2 , 2010, Journal of biomedicine & biotechnology.

[124]  W. Ellmeier,et al.  Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production , 2010, The Journal of Immunology.

[125]  Edwin Smith,et al.  The Language of Histone Crosstalk , 2010, Cell.

[126]  Min Zhang,et al.  p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor , 2010, The Journal of Immunology.

[127]  E. Verdin,et al.  Regulatory signal transduction pathways for class IIa histone deacetylases. , 2010, Current opinion in pharmacology.

[128]  S. McMahon,et al.  Rise of the Rival , 2010, Science.

[129]  E. Kalkhoven,et al.  Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. , 2010, Blood.

[130]  H. Sai,et al.  Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice. , 2010, Gastroenterology.

[131]  M. McBurney,et al.  The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. , 2009, The Journal of clinical investigation.

[132]  Dustin E. Schones,et al.  Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes , 2009, Cell.

[133]  M. Mann,et al.  Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions , 2009, Science.

[134]  Huadong Liu,et al.  Molecular Characterization of Propionyllysines in Non-histone Proteins *S , 2009, Molecular & Cellular Proteomics.

[135]  D. H. Kim,et al.  A Novel Germ Cell-specific Protein, SHIP1, Forms a Complex with Chromatin Remodeling Activity during Spermatogenesis* , 2008, Journal of Biological Chemistry.

[136]  D. Schrenk,et al.  Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. , 2008, The Journal of nutritional biochemistry.

[137]  E. Seto,et al.  Lysine acetylation: codified crosstalk with other posttranslational modifications. , 2008, Molecular cell.

[138]  Michael Q. Zhang,et al.  Combinatorial patterns of histone acetylations and methylations in the human genome , 2008, Nature Genetics.

[139]  Jun Qin,et al.  Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells , 2008, Nature Cell Biology.

[140]  Minoru Yoshida,et al.  HDAC6 a new cellular stress surveillance factor , 2008, Cell cycle.

[141]  E. Olson,et al.  Deacetylase inhibition promotes the generation and function of regulatory T cells , 2007, Nature Medicine.

[142]  U. Koch,et al.  Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases , 2007, Proceedings of the National Academy of Sciences.

[143]  C. Boyault,et al.  HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination , 2007, Oncogene.

[144]  Jerry L. Workman,et al.  Histone acetyltransferase complexes: one size doesn't fit all , 2007, Nature Reviews Molecular Cell Biology.

[145]  Yuan Shen,et al.  FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression , 2007, Proceedings of the National Academy of Sciences.

[146]  J. Bradner,et al.  Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. , 2006, Molecular biology of the cell.

[147]  Eric Verdin,et al.  Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 , 2006, Proceedings of the National Academy of Sciences.

[148]  W. C. Hallows,et al.  Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases , 2006, Proceedings of the National Academy of Sciences.

[149]  Yingming Zhao,et al.  HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription. , 2006, Molecular cell.

[150]  G. Stephanopoulos,et al.  Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis , 2005, Journal of Neuroimmunology.

[151]  C. Caron,et al.  Regulatory cross‐talk between lysine acetylation and ubiquitination: role in the control of protein stability , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.

[152]  Xiang-Jiao Yang,et al.  Class II Histone Deacetylases: from Sequence to Function, Regulation, and Clinical Implication , 2005, Molecular and Cellular Biology.

[153]  J. O’Shea,et al.  Discrete Roles for Histone Acetylation in Human T Helper 1 Cell-specific Gene Expression* , 2004, Journal of Biological Chemistry.

[154]  T. Malek,et al.  Tolerance, not immunity, crucially depends on IL-2 , 2004, Nature Reviews Immunology.

[155]  L. Augenlicht,et al.  Requirement of Histone Deacetylase Activity for Signaling by STAT1* , 2004, Journal of Biological Chemistry.

[156]  Wun-Jae Kim,et al.  Transforming Growth Factor-β Stimulates p300-dependent RUNX3 Acetylation, Which Inhibits Ubiquitination-mediated Degradation* , 2004, Journal of Biological Chemistry.

[157]  Ivan V. Gregoretti,et al.  Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. , 2004, Journal of molecular biology.

[158]  J. Vance,et al.  The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress , 2003, Cell.

[159]  F. Dequiedt,et al.  Class II histone deacetylases: versatile regulators. , 2003, Trends in genetics : TIG.

[160]  B. Olde,et al.  Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. , 2003, Biochemical and biophysical research communications.

[161]  G. Gilkeson,et al.  Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. , 2003, The Journal of clinical investigation.

[162]  R. Flavell,et al.  Cutting Edge: Changes in Histone Acetylation at the IL-4 and IFN-γ Loci Accompany Th1/Th2 Differentiation , 2002, The Journal of Immunology.

[163]  Fred Asselbergs,et al.  Cloning and Functional Characterization of HDAC11, a Novel Member of the Human Histone Deacetylase Family* , 2002, The Journal of Biological Chemistry.

[164]  Anjana Rao,et al.  TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes , 2002, Nature Immunology.

[165]  J. Schroeder,et al.  Histone deacetylation inhibits IL4 gene expression in T cells. , 2002, The Journal of allergy and clinical immunology.

[166]  M. Guenther,et al.  The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3 , 2001, Molecular and Cellular Biology.

[167]  P. Brehm,et al.  Regulation of Neuronal Traits by a Novel Transcriptional Complex , 2001, Neuron.

[168]  C. Allis,et al.  Translating the Histone Code , 2001, Science.

[169]  M. Posch,et al.  Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1. , 2001, Journal of molecular biology.

[170]  T. Yamagata,et al.  Acetylation of GATA‐3 affects T‐cell survival and homing to secondary lymphoid organs , 2000, The EMBO journal.

[171]  J. Qin,et al.  Both corepressor proteins SMRT and N‐CoR exist in large protein complexes containing HDAC3 , 2000, The EMBO journal.

[172]  R. Shiekhattar,et al.  A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. , 2000, Genes & Development.

[173]  A. Verdel,et al.  Identification of a New Family of Higher Eukaryotic Histone Deacetylases , 1999, The Journal of Biological Chemistry.

[174]  Weidong Wang,et al.  NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. , 1998, Molecular cell.

[175]  S. Schreiber,et al.  Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex , 1998, Nature.

[176]  D. Reinberg,et al.  The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities , 1998, Cell.

[177]  Chyung-Ru Wang,et al.  Helper T cell differentiation is controlled by the cell cycle. , 1998, Immunity.

[178]  A. Wolffe,et al.  A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase , 1998, Current Biology.

[179]  S. Schreiber,et al.  A role for histone deacetylase activity in HDAC1-mediated transcriptional repression. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[180]  Wen‐Ming Yang,et al.  Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression , 1997, Cell.

[181]  D. Reinberg,et al.  Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex , 1997, Cell.

[182]  Stuart L Schreiber,et al.  Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A , 1997, Cell.

[183]  L. Chin,et al.  Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression , 1997, nature.

[184]  C. Glass,et al.  A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression , 1997, nature.

[185]  D. Phillips The presence of acetyl groups of histones. , 1963, The Biochemical journal.

[186]  C. Bock,et al.  A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis. , 2018, Journal of Autoimmunity.

[187]  Johan Auwerx,et al.  Protein acetylation in metabolism — metabolites and cofactors , 2016, Nature Reviews Endocrinology.

[188]  Lisa A. Raedler Farydak (Panobinostat): First HDAC Inhibitor Approved for Patients with Relapsed Multiple Myeloma. , 2016, American health & drug benefits.

[189]  S. Jameson,et al.  Innate memory T cells. , 2015, Advances in immunology.

[190]  M. Kronenberg,et al.  Activation and Function of iNKT and MAIT Cells. , 2015, Advances in immunology.

[191]  Jinfang Zhu,et al.  Transcriptional regulatory networks for CD4 T cell differentiation. , 2014, Current topics in microbiology and immunology.

[192]  K. Asadullah,et al.  Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors. , 2009, Cellular immunology.

[193]  E. Olson,et al.  The many roles of histone deacetylases in development and physiology: implications for disease and therapy , 2009, Nature Reviews Genetics.

[194]  A. Kozyrskyj,et al.  Epigenetic regulation of established human type 1 versus type 2 cytokine responses. , 2008, The Journal of allergy and clinical immunology.

[195]  F. Dequiedt,et al.  Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. , 2002, Molecular cell.