Chidamide alleviates TGF-β-induced epithelial–mesenchymal transition in lung cancer cell lines

[1]  R. Johnstone,et al.  Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders , 2015, Nature Reviews Drug Discovery.

[2]  Samy Lamouille,et al.  Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.

[3]  L. R. Carpio,et al.  Histone Deacetylase 3 Suppression Increases PH Domain and Leucine-rich Repeat Phosphatase (Phlpp)1 Expression in Chondrocytes to Suppress Akt Signaling and Matrix Secretion* , 2013, The Journal of Biological Chemistry.

[4]  P. Massion,et al.  Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin , 2012, Molecular Cancer Therapeutics.

[5]  J. Neal,et al.  Complex role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[6]  M. Fu,et al.  Antitumor activity of Chidamide in hepatocellular carcinoma cell lines. , 2012, Molecular medicine reports.

[7]  Chih-Hsien Wu,et al.  Nickel-induced Epithelial-Mesenchymal Transition by Reactive Oxygen Species Generation and E-cadherin Promoter Hypermethylation* , 2012, The Journal of Biological Chemistry.

[8]  Jun Yao,et al.  G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer. , 2012, The Journal of clinical investigation.

[9]  Guojun Li,et al.  Lymphangiogenesis and biological behavior in pancreatic carcinoma and other pancreatic tumors , 2012, Molecular medicine reports.

[10]  F. Setién,et al.  Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context , 2011, Nucleic acids research.

[11]  H. Chan,et al.  N-acetyl cysteine mitigates curcumin-mediated telomerase inhibition through rescuing of Sp1 reduction in A549 cells. , 2010, Mutation research.

[12]  J. Jen,et al.  TGF-&bgr; Signaling and the Role of Inhibitory Smads in Non-small Cell Lung Cancer , 2010, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[13]  M-F Chen,et al.  Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells , 2008, Cancer Gene Therapy.

[14]  K. Miyazaki,et al.  Aberrant Gene Methylation in the Lymph Nodes Provides a Possible Marker for Diagnosing Micrometastasis in Gastric Cancer , 2010, Annals of Surgical Oncology.

[15]  J. Chirgwin,et al.  Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment , 2009, PloS one.

[16]  Samy Lamouille,et al.  TGF-β-induced epithelial to mesenchymal transition , 2009, Cell Research.

[17]  T. Brabletz,et al.  A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells , 2008, EMBO reports.

[18]  E. Cho,et al.  Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to promoter region in human cervix cancer cells , 2008, Oncogene.

[19]  Ya‐Wen Cheng,et al.  Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. , 2007, Cancer research.

[20]  E. Seto,et al.  Histone deacetylases and cancer , 2007, Oncogene.

[21]  Manel Esteller,et al.  The role of histone deacetylases (HDACs) in human cancer , 2007, Molecular oncology.

[22]  J Downward,et al.  Raf plus TGFβ-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin , 2006, Oncogene.

[23]  Kelly M. McGarvey,et al.  Inhibition of SIRT1 Reactivates Silenced Cancer Genes without Loss of Promoter DNA Hypermethylation , 2006, PLoS genetics.

[24]  J. Minna,et al.  Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. , 2006, Cancer research.

[25]  E. Ballestar,et al.  Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex , 2004, Molecular and Cellular Biology.

[26]  G. Strathdee Epigenetic versus genetic alterations in the inactivation of E-cadherin. , 2002, Seminars in cancer biology.