Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems

[1]  C. Meyer.  Message in a bottle. , 2020, Minnesota medicine.

[2]  M. Amiji,et al.  Exosome mediated communication within the tumor microenvironment. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[3]  M. Amiji,et al.  Modulation of Macrophage Functional Polarity towards Anti-Inflammatory Phenotype with Plasmid DNA Delivery in CD44 Targeting Hyaluronic Acid Nanoparticles , 2015, Scientific Reports.

[4]  Z. Duan,et al.  Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer , 2015, Pharmaceutical Research.

[5]  Z. Duan,et al.  MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer , 2015, Scientific Reports.

[6]  M. Bijlsma,et al.  The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal , 2015, Cancer and Metastasis Reviews.

[7]  M. Amiji,et al.  Macrophage-targeted delivery systems for nucleic acid therapy of inflammatory diseases. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[8]  M. Ebsen,et al.  Tumor‐associated macrophages exhibit pro‐ and anti‐inflammatory properties by which they impact on pancreatic tumorigenesis , 2014, International journal of cancer.

[9]  D. Edbauer,et al.  Good guy or bad guy: the opposing roles of microRNA 125b in cancer , 2014, Cell Communication and Signaling.

[10]  D. Edbauer,et al.  Good guy or bad guy: the opposing roles of microRNA 125b in cancer , 2014, Cell Communication and Signaling.

[11]  M. Lotze,et al.  Good things come in small packages: exosomes, immunity and cancer , 2014, Cancer Gene Therapy.

[12]  G. Emekdas,et al.  Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma , 2014, Molecular Biology Reports.

[13]  G. Calin,et al.  Clinical relevance of circulating cell-free microRNAs in cancer , 2014, Nature Reviews Clinical Oncology.

[14]  H. Repo,et al.  Anti-inflammatory macrophages activate invasion in pancreatic adenocarcinoma by increasing the MMP9 and ADAM8 expression , 2014, Medical Oncology.

[15]  M. Ratajczak,et al.  Exosomes: an overview of biogenesis, composition and role in ovarian cancer , 2014, Journal of Ovarian Research.

[16]  Arun K Iyer,et al.  In vivo biodistribution of siRNA and cisplatin administered using CD44-targeted hyaluronic acid nanoparticles. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[17]  L. Coussens,et al.  CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8+ T cells , 2013, Oncoimmunology.

[18]  M. Fabbri,et al.  MicroRNAs and other non-coding RNAs as targets for anticancer drug development , 2013, Nature Reviews Drug Discovery.

[19]  L. Naldini,et al.  A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice. , 2013, Blood.

[20]  Kwangmeyung Kim,et al.  Robust PEGylated hyaluronic acid nanoparticles as the carrier of doxorubicin: mineralization and its effect on tumor targetability in vivo. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[21]  Thomas A. Wynn,et al.  Macrophage biology in development, homeostasis and disease , 2013, Nature.

[22]  F. Mattei,et al.  The Tumor Microenvironment: A Pitch for Multiple Players , 2013, Front. Oncol..

[23]  Arun K Iyer,et al.  Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors. , 2013, Biomaterials.

[24]  Michael C. Schmid,et al.  Impact of tumour associated macrophages in pancreatic cancer , 2013, BMB reports.

[25]  N. Shen,et al.  MicroRNA involvement in lupus: the beginning of a new tale , 2012, Current opinion in rheumatology.

[26]  Qiao Li,et al.  Tumor cell-derived exosomes: a message in a bottle. , 2012, Biochimica et biophysica acta.

[27]  Alexander A. Fingerle,et al.  The role of stroma in pancreatic cancer: diagnostic and therapeutic implications , 2012, Nature Reviews Gastroenterology &Hepatology.

[28]  R. Setterquist,et al.  Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials. , 2012, Biochimica et biophysica acta.

[29]  C. Chen,et al.  Exosome removal as a therapeutic adjuvant in cancer , 2012, Journal of Translational Medicine.

[30]  Anton P. McCaffrey,et al.  Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes* , 2012, The Journal of Biological Chemistry.

[31]  Clotilde Théry,et al.  Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses , 2011, Traffic.

[32]  P. Robbins,et al.  The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis , 2011, Clinical & developmental immunology.

[33]  Ryan M. O’Connell,et al.  MicroRNA-125b Potentiates Macrophage Activation , 2011, The Journal of Immunology.

[34]  Jinming Gao,et al.  Overcoming endosomal barrier by amphotericin B-loaded dual pH-responsive PDMA-b-PDPA micelleplexes for siRNA delivery. , 2011, ACS nano.

[35]  I. Holen,et al.  Tumour macrophages as potential targets of bisphosphonates , 2011, Journal of Translational Medicine.

[36]  J. Neoptolemos.  Adjuvant treatment of pancreatic cancer. , 2011, European journal of cancer.

[37]  Liu Yu,et al.  Influence of tumor associated macrophages on biological function of SW620 cell. , 2011, Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae.

[38]  W. Grizzle,et al.  Exosomes and Cancer: A Newly Described Pathway of Immune Suppression , 2011, Clinical Cancer Research.

[39]  E. Wang,et al.  Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells , 2010, BMC Cancer.

[40]  Crislyn D'Souza-Schorey,et al.  Microvesicles: mediators of extracellular communication during cancer progression , 2010, Journal of Cell Science.

[41]  Alberto Mantovani,et al.  Macrophages, innate immunity and cancer: balance, tolerance, and diversity. , 2010, Current opinion in immunology.

[42]  I. Faraoni,et al.  miR-155 gene: a typical multifunctional microRNA. , 2009, Biochimica et biophysica acta.

[43]  P. Allavena,et al.  Cancer-related inflammation , 2008, Nature.

[44]  C. Croce,et al.  MicroRNA-cancer connection: the beginning of a new tale. , 2006, Cancer research.

[45]  F. Slack,et al.  Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.

[46]  Silvano Sozzani,et al.  The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.

[47]  H. Friess,et al.  Detection and localization of MIP‐3α/LARC/exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer , 1999 .

[48]  M. Hojo,et al.  DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS , 1978 .

[49]  Mario Acunzo,et al.  MicroRNA and cancer--a brief overview. , 2015, Advances in biological regulation.

[50]  Bin He,et al.  Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery. , 2013, Biomaterials.

[51]  E. Eruslanov,et al.  Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer. , 2012, American journal of translational research.

[52]  Laura H. Tang,et al.  Survival after Resection of Pancreatic Adenocarcinoma: Results from a Single Institution over Three Decades , 2011, Annals of Surgical Oncology.

[53]  Yusuke Nakamura,et al.  Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma , 2009, Journal of Gastroenterology.