Ryanodine receptors: physiological function and deregulation in Alzheimer disease
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[1] Grace E. Stutzmann,et al. Calcium channelopathies and Alzheimer's disease: insight into therapeutic success and failures. , 2014, European journal of pharmacology.
[2] L. Good,et al. The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease , 2014, Channels.
[3] I. Bezprozvanny,et al. Can the Calcium Hypothesis Explain Synaptic Loss in Alzheimer's Disease? , 2013, Neurodegenerative Diseases.
[4] Jie Shen,et al. Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons , 2013, Proceedings of the National Academy of Sciences.
[5] C. Hidalgo,et al. Amyloid β-peptide oligomers, ryanodine receptor-mediated Ca2+ release, and Wnt-5a/Ca2+ signaling: opposing roles in neuronal mitochondrial dynamics? , 2013, Front. Cell. Neurosci..
[6] Samuel Bandara,et al. Regulators of Calcium Homeostasis Identified by Inference of Kinetic Model Parameters from Live Single Cells Perturbed by siRNA , 2013, Science Signaling.
[7] J. Molinuevo,et al. A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease , 2013, Neurobiology of Aging.
[8] I. Parker,et al. Cytotoxicity of Intracellular Aβ42 Amyloid Oligomers Involves Ca2+ Release from the Endoplasmic Reticulum by Stimulated Production of Inositol Trisphosphate , 2013, The Journal of Neuroscience.
[9] D. Macmillan,et al. FK506 binding proteins: cellular regulators of intracellular Ca2+ signalling. , 2013, European journal of pharmacology.
[10] P. Papazafiri,et al. Downregulation of AβPP enhances both calcium content of endoplasmic reticulum and acidic stores and the dynamics of store operated calcium channel activity. , 2013, Journal of Alzheimer's disease : JAD.
[11] J. Richardson,et al. Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease , 2012, PloS one.
[12] K. Wada,et al. Calcium leak through ryanodine receptor is involved in neuronal death induced by mutant huntingtin. , 2012, Biochemical and biophysical research communications.
[13] BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease , 2012, Molecular Neurodegeneration.
[14] T. Pozzan,et al. Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2 , 2012, Aging cell.
[15] M. Wolfe. Processive proteolysis by γ-secretase and the mechanism of Alzheimer’s disease , 2012, Biological chemistry.
[16] O. Arancio,et al. Role of Leaky Neuronal Ryanodine Receptors in Stress- Induced Cognitive Dysfunction , 2012, Cell.
[17] F. Benfenati,et al. Ryanodine Receptor Blockade Reduces Amyloid-β Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease , 2012, The Journal of Neuroscience.
[18] H. Das,et al. Repression of transcription of presenilin‐1 inhibits γ‐secretase independent ER Ca2+ leak that is impaired by FAD mutations , 2012, Journal of neurochemistry.
[19] J. Molgó,et al. Early Presynaptic and Postsynaptic Calcium Signaling Abnormalities Mask Underlying Synaptic Depression in Presymptomatic Alzheimer's Disease Mice , 2012, The Journal of Neuroscience.
[20] B. Strooper,et al. Response to Shilling et al. , 2012 .
[21] J. Foskett,et al. Reply to Bezprozvanny et al.: Response to Shilling et al. (10.1074/jbc.M111.300491) , 2012, The Journal of Biological Chemistry.
[22] B. de Strooper,et al. Response to Shilling et al. (10.1074/jbc.M111.300491) , 2012, The Journal of Biological Chemistry.
[23] M. Eckenhoff,et al. Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice , 2012, Neuroscience Letters.
[24] D. Bennett,et al. Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease , 2012, Neurobiology of Aging.
[25] J. A. Dani,et al. Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's disease , 2012, Neurobiology of Aging.
[26] Laura Iop,et al. Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia , 2012, EMBO molecular medicine.
[27] L. Blatter,et al. Dantrolene prevents arrhythmogenic Ca2+ release in heart failure. , 2012, American journal of physiology. Heart and circulatory physiology.
[28] D. Kang,et al. Lack of Evidence for Presenilins as Endoplasmic Reticulum Ca2+ Leak Channels* , 2012, The Journal of Biological Chemistry.
[29] M. Sharifzadeh,et al. Inhibition of PKA attenuates memory deficits induced by β-amyloid (1–42), and decreases oxidative stress and NF-κB transcription factors , 2012, Behavioural Brain Research.
[30] F. Checler,et al. The physiology of the β‐amyloid precursor protein intracellular domain AICD , 2012, Journal of neurochemistry.
[31] J. Richardson,et al. Stabilizing ER Ca 2 + Channel Function as an Early Preventative Strategy for Alzheimer ’ s Disease , 2012 .
[32] X. Chen,et al. Dantrolene is neuroprotective in Huntington's disease transgenic mouse model , 2011, Molecular Neurodegeneration.
[33] M. Mattson,et al. Endoplasmic Reticulum Ca2+ Handling in Excitable Cells in Health and Disease , 2011, Pharmacological Reviews.
[34] T. Shiomi,et al. Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging. , 2011, Cell metabolism.
[35] S. Reiken,et al. Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion , 2011, Proceedings of the National Academy of Sciences.
[36] Grace E. Stutzmann,et al. Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction , 2011, Science China Life Sciences.
[37] D. Rincon-Limas,et al. The ER stress factor XBP1s prevents amyloid-beta neurotoxicity. , 2011, Human molecular genetics.
[38] B. de Strooper,et al. Mutagenesis Mapping of the Presenilin 1 Calcium Leak Conductance Pore* , 2011, The Journal of Biological Chemistry.
[39] C. Hetz,et al. Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF. , 2011, Antioxidants & redox signaling.
[40] E. Blalock,et al. Disrupting Function of FK506-Binding Protein 1b/12.6 Induces the Ca2+-Dysregulation Aging Phenotype in Hippocampal Neurons , 2011, The Journal of Neuroscience.
[41] T. Wagenknecht,et al. Localization of the Dantrolene-binding Sequence near the FK506-binding Protein-binding Site in the Three-dimensional Structure of the Ryanodine Receptor* , 2011, The Journal of Biological Chemistry.
[42] M. Zoli,et al. Ryanodine receptor‐2 upregulation and nicotine‐mediated plasticity , 2011, The EMBO journal.
[43] Huaxi Xu,et al. APP processing in Alzheimer's disease , 2011, Molecular Brain.
[44] Dimitra K. Georgiou,et al. Ryanodine receptors: structure, expression, molecular details, and function in calcium release. , 2010, Cold Spring Harbor perspectives in biology.
[45] Ivan V. Goussakov,et al. NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice , 2010, The Journal of Neuroscience.
[46] Debashis Mukhopadhyay,et al. AICD Overexpression in Neuro 2A Cells Regulates Expression of PTCH1 and TRPC5 , 2010, International journal of Alzheimer's disease.
[47] L. Hui,et al. HGF suppresses high glucose-mediated oxidative stress in mesangial cells by activation of PKG and inhibition of PKA. , 2010, Free radical biology & medicine.
[48] B. de Strooper,et al. Role of Presenilins in Neuronal Calcium Homeostasis , 2010, The Journal of Neuroscience.
[49] W. Klein,et al. Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5 , 2010, Neuron.
[50] M. Mattson. ER Calcium and Alzheimer’s Disease: In a State of Flux , 2010, Science Signaling.
[51] I. Bezprozvanny,et al. The dysregulation of intracellular calcium in Alzheimer disease. , 2010, Cell calcium.
[52] J. Bradley,et al. Up‐regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer’s disease , 2010, Journal of neurochemistry.
[53] C. Ward,et al. Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle , 2009, Neurobiology of Aging.
[54] I. Bezprozvanny,et al. Familial Alzheimer's disease mutations in presenilins: effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes. , 2010, Journal of Alzheimer's disease : JAD.
[55] Thomas G. Oertner,et al. Differential distribution of endoplasmic reticulum controls metabotropic signaling and plasticity at hippocampal synapses , 2009, Proceedings of the National Academy of Sciences.
[56] Ivan V. Goussakov,et al. Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice , 2009, The Journal of Neuroscience.
[57] S. Pulst,et al. Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 2 , 2009, The Journal of Neuroscience.
[58] T. Südhof,et al. Presenilins are Essential for Regulating Neurotransmitter Release , 2009, Nature.
[59] S. Currie. Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right. , 2009, Frontiers in bioscience.
[60] M. Yano,et al. Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor. , 2009, Journal of the American College of Cardiology.
[61] T. Pozzan,et al. Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake , 2009, Journal of cellular and molecular medicine.
[62] Y. Gong,et al. Effect of amyloid β on capacitive calcium entry in neural 2a cells , 2009, Brain Research Bulletin.
[63] T. Miyakawa,et al. Comprehensive Behavioral Phenotyping of Ryanodine Receptor type 3 (RyR3) Knockout Mice: Decreased Social Contact Duration in Two Social Interaction Tests , 2009, Front. Behav. Neurosci..
[64] S. Matecki,et al. Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle , 2009, Nature Medicine.
[65] R. Nicoll,et al. Differential trafficking of AMPA and NMDA receptors by SAP102 and PSD-95 underlies synapse development , 2008, Proceedings of the National Academy of Sciences.
[66] X. Chen,et al. Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3 , 2008, The Journal of Neuroscience.
[67] P. Koulen,et al. The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein-protein interaction. , 2008, Cell calcium.
[68] Arthur Konnerth,et al. Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease , 2008, Science.
[69] J. Gálvez,et al. Ischemia Enhances Activation by Ca2+ and Redox Modification of Ryanodine Receptor Channels from Rat Brain Cortex , 2008, The Journal of Neuroscience.
[70] Ilya Bezprozvanny,et al. Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease , 2008, Trends in Neurosciences.
[71] Ian Parker,et al. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. , 2008, The Journal of general physiology.
[72] O. Arancio,et al. Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease. , 2008, The Journal of clinical investigation.
[73] Brian J. Bacskai,et al. Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks , 2008, Neuron.
[74] F. LaFerla,et al. SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production , 2008, The Journal of cell biology.
[75] V. Lee,et al. Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating , 2008, Neuron.
[76] F. LaFerla,et al. Increased intraneuronal resting [Ca2+] in adult Alzheimer’s disease mice , 2008, Journal of neurochemistry.
[77] S. Reiken,et al. Remodeling of ryanodine receptor complex causes “leaky” channels: A molecular mechanism for decreased exercise capacity , 2008, Proceedings of the National Academy of Sciences.
[78] J. Segura-Aguilar,et al. Effect of the knockdown of amyloid precursor protein on intracellular calcium increases in a neuronal cell line derived from the cerebral cortex of a trisomy 16 mouse , 2008, Experimental Neurology.
[79] P. Koulen,et al. The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. , 2008, The international journal of biochemistry & cell biology.
[80] N. Arispe,et al. The Cell-Selective Neurotoxicity of the Alzheimer's Aβ Peptide Is Determined by Surface Phosphatidylserine and Cytosolic ATP Levels. Membrane Binding Is Required for Aβ Toxicity , 2007, The Journal of Neuroscience.
[81] G. Taglialatela,et al. Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice , 2007, Neurobiology of Learning and Memory.
[82] Stephan E Lehnart,et al. Modulation of the ryanodine receptor and intracellular calcium. , 2007, Annual review of biochemistry.
[83] B. de Strooper,et al. Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1. , 2007, The Journal of clinical investigation.
[84] B. Strooper. Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease. , 2007 .
[85] M. Wolfe. When loss is gain: reduced presenilin proteolytic function leads to increased Aβ42/Aβ40 , 2007 .
[86] F. LaFerla,et al. Enhanced Ryanodine‐Mediated Calcium Release in Mutant PS1‐Expressing Alzheimer's Mouse Models , 2007, Annals of the New York Academy of Sciences.
[87] M. Wolfe. When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease. , 2007, EMBO reports.
[88] D. Westaway,et al. Amyloid-β-(1-42) Increases Ryanodine Receptor-3 Expression and Function in Neurons of TgCRND8 Mice* , 2006, Journal of Biological Chemistry.
[89] M. Brotto,et al. Azumolene Inhibits a Component of Store-operated Calcium Entry Coupled to the Skeletal Muscle Ryanodine Receptor* , 2006, Journal of Biological Chemistry.
[90] M. Beal,et al. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases , 2006, Nature.
[91] B. Strooper,et al. Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations , 2006, Cell.
[92] F. LaFerla,et al. Enhanced Ryanodine Receptor Recruitment Contributes to Ca2+ Disruptions in Young, Adult, and Aged Alzheimer's Disease Mice , 2006, The Journal of Neuroscience.
[93] N. Arispe,et al. Early and Late Cytotoxic Effects of External Application of the Alzheimer's Aβ Result from the Initial Formation and Function of Aβ Ion Channels† , 2006 .
[94] N. Emptage,et al. The role of the endoplasmic reticulum Ca2+ store in the plasticity of central neurons. , 2006, Trends in pharmacological sciences.
[95] Stephen J Redman,et al. Spatial segregation of neuronal calcium signals encodes different forms of LTP in rat hippocampus , 2006, The Journal of physiology.
[96] R. Bullock. Efficacy and Safety of Memantine in Moderate-to-Severe Alzheimer Disease: The Evidence to Date , 2006, Alzheimer disease and associated disorders.
[97] Jae Woong Lee,et al. PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release. , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[98] N. Arispe,et al. Early and late cytotoxic effects of external application of the Alzheimer's Abeta result from the initial formation and function of Abeta ion channels. , 2006, Biochemistry.
[99] M. Hori,et al. Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[100] F. LaFerla,et al. Enhanced caffeine‐induced Ca2+ release in the 3xTg‐AD mouse model of Alzheimer's disease , 2005, Journal of neurochemistry.
[101] C. Oliveira,et al. The role of calcineurin in amyloid-β-peptides-mediated cell death , 2005, Brain Research.
[102] P. Williams,et al. Probing a putative dantrolene-binding site on the cardiac ryanodine receptor. , 2005, The Biochemical journal.
[103] Ian Parker,et al. Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers*♦ , 2005, Journal of Biological Chemistry.
[104] R. Tanzi,et al. Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective , 2005, Cell.
[105] C. Oliveira,et al. The role of calcineurin in amyloid-beta-peptides-mediated cell death. , 2005, Brain research.
[106] M. Bear,et al. LTP and LTD An Embarrassment of Riches , 2004, Neuron.
[107] C. Masters,et al. Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[108] C. Oliveira,et al. Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5‐triphosphate receptors in the neurotoxic effects induced by the amyloid‐β peptide , 2004, Journal of neuroscience research.
[109] J. Lindeboom,et al. Neuropsychology of cognitive ageing, minimal cognitive impairment, Alzheimer's disease, and vascular cognitive impairment. , 2004, European journal of pharmacology.
[110] E. Kandel,et al. Loss of Presenilin Function Causes Impairments of Memory and Synaptic Plasticity Followed by Age-Dependent Neurodegeneration , 2004, Neuron.
[111] Colin L. Masters,et al. Neurodegenerative diseases and oxidative stress , 2004, Nature Reviews Drug Discovery.
[112] B. Winblad,et al. γ-Secretase Activity of Presenilin 1 Regulates Acetylcholine Muscarinic Receptor-mediated Signal Transduction* , 2004, Journal of Biological Chemistry.
[113] Grace E Stutzmann,et al. Dysregulated IP3 Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation in Presenilin1 Results in Exaggerated Ca2+ Signals and Altered Membrane Excitability , 2004, The Journal of Neuroscience.
[114] A. Schousboe,et al. Glutamate receptor activation in cultured cerebellar granule cells increases cytosolic free Ca2+ by mobilization of cellular Ca2+ and activation of Ca2+ influx , 2004, Experimental Brain Research.
[115] J. Ryder,et al. Inhibition of Aβ production and APP maturation by a specific PKA inhibitor , 2003 .
[116] M. Berridge,et al. Calcium signalling: dynamics, homeostasis and remodelling , 2003, Nature reviews. Molecular cell biology.
[117] T. Foster,et al. Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment , 2003, The Journal of Neuroscience.
[118] J. Geiger,et al. Presence and functional significance of presynaptic ryanodine receptors , 2003, Progress in Neurobiology.
[119] Ian Parker,et al. Ca2+ Signaling in Mouse Cortical Neurons Studied by Two-Photon Imaging and Photoreleased Inositol Triphosphate , 2003, The Journal of Neuroscience.
[120] G. Collingridge,et al. Calcium stores and synaptic plasticity. , 2002, Cell calcium.
[121] M. Berridge,et al. The endoplasmic reticulum: a multifunctional signaling organelle. , 2002, Cell calcium.
[122] M. Sajin,et al. Dantrolene protects neurons against kainic acid induced apoptosis in vitro and in vivo , 2002, Journal of cellular and molecular medicine.
[123] B. de Strooper,et al. A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[124] H. Terasaki,et al. Effects of Dantrolene on Extracellular Glutamate Concentration and Neuronal Death in the Rat Hippocampal CA1 Region Subjected to Transient Ischemia , 2002, Anesthesiology.
[125] B. de Strooper,et al. A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP. , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[126] G. Meissner,et al. Modulation of Intracellular Calcium-Release Channels by Calmodulin , 2002, The Journal of Membrane Biology.
[127] W. Regehr,et al. Short-term synaptic plasticity. , 2002, Annual review of physiology.
[128] Thomas C. Südhof,et al. A Transcriptively Active Complex of APP with Fe65 and Histone Acetyltransferase Tip60 , 2001, Science.
[129] Masahiko Watanabe,et al. Postsynaptic Modulation of AMPA Receptor-Mediated Synaptic Responses and LTP by the Type 3 Ryanodine Receptor , 2001, Molecular and Cellular Neuroscience.
[130] C. Louis,et al. Dantrolene Inhibition of Ryanodine Receptor Ca2+Release Channels , 2001, The Journal of Biological Chemistry.
[131] Alan Fine,et al. Calcium Stores in Hippocampal Synaptic Boutons Mediate Short-Term Plasticity, Store-Operated Ca2+ Entry, and Spontaneous Transmitter Release , 2001, Neuron.
[132] T. Südhof,et al. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. , 2001, Science.
[133] M. Poo,et al. Calcium stores regulate the polarity and input specificity of synaptic modification , 2000, Nature.
[134] A. Delacourte,et al. Tau pathology: a marker of neurodegenerative disorders , 2000, Current opinion in neurology.
[135] Rafael Yuste,et al. From form to function: calcium compartmentalization in dendritic spines , 2000, Nature Neuroscience.
[136] M. Mattson,et al. Presenilin-1 Mutations Increase Levels of Ryanodine Receptors and Calcium Release in PC12 Cells and Cortical Neurons* , 2000, The Journal of Biological Chemistry.
[137] R. Tanzi,et al. Presenilin 2 Interacts with Sorcin, a Modulator of the Ryanodine Receptor* , 2000, The Journal of Biological Chemistry.
[138] P. Hyslop,et al. Inhibition of abeta production and APP maturation by specific PKA inhibitors , 2000, Neurobiology of Aging.
[139] D. Alkon,et al. Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[140] F. LaFerla,et al. Presenilin-2 Mutations Modulate Amplitude and Kinetics of Inositol 1,4,5-Trisphosphate-mediated Calcium Signals* , 1999, The Journal of Biological Chemistry.
[141] K. Mikoshiba,et al. Facilitation of NMDAR-Independent LTP and Spatial Learning in Mutant Mice Lacking Ryanodine Receptor Type 3 , 1999, Neuron.
[142] J. Fastbom,et al. Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies , 1999, Neuroscience.
[143] J C Reed,et al. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. , 1999, Science.
[144] T. Furuyama,et al. The Cell Death-promoting Gene DP5, Which Interacts with the BCL2 Family, Is Induced during Neuronal Apoptosis Following Exposure to Amyloid β Protein* , 1999, The Journal of Biological Chemistry.
[145] F. Checler,et al. Effect of protein kinase A inhibitors on the production of Aβ40 and Aβ42 by human cells expressing normal and Alzheimer's disease‐linked mutated βAPP and presenilin 1 , 1999, British journal of pharmacology.
[146] F. Checler,et al. Effect of protein kinase A inhibitors on the production of Abeta40 and Abeta42 by human cells expressing normal and Alzheimer's disease-linked mutated betaAPP and presenilin 1. , 1999, British journal of pharmacology.
[147] H. Valdivia,et al. Modulation of intracellular Ca2+ levels in the heart by sorcin and FKBP12, two accessory proteins of ryanodine receptors. , 1998, TIPS - Trends in Pharmacological Sciences.
[148] Sebastiano Cavallaro,et al. Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade , 1998, Trends in Neurosciences.
[149] F. Checler,et al. Post-transcriptional Contribution of a cAMP-dependent Pathway to the Formation of α- and β/γ-Secretases-Derived Products of βAPP Maturation in Human Cells Expressing Wild-type and Swedish Mutated βAPP , 1998, Molecular medicine.
[150] Peter Lipp,et al. Calcium - a life and death signal , 1998, Nature.
[151] D. Alkon,et al. Calcium Responses in Fibroblasts from Asymptomatic Members of Alzheimer's Disease Families , 1998, Neurobiology of Disease.
[152] M. Segal,et al. Fast confocal imaging of calcium released from stores in dendritic spines , 1998, The European journal of neuroscience.
[153] Roger Y. Tsien,et al. Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression , 1998, Nature.
[154] J. Meldolesi,et al. The endoplasmic reticulum Ca2+ store: a view from the lumen. , 1998, Trends in biochemical sciences.
[155] D. Alkon,et al. Abnormalities in Alzheimer’s Disease Fibroblasts Bearing the APP670/671 Mutation , 1997, Neurobiology of Aging.
[156] J. Mickelson,et al. Dantrolene Inhibition of Sarcoplasmic Reticulum Ca2+Release by Direct and Specific Action at Skeletal Muscle Ryanodine Receptors* , 1997, The Journal of Biological Chemistry.
[157] D. Selkoe,et al. Caffeine Stimulates Amyloid β‐Peptide Release from β‐Amyloid Precursor Protein‐Transfected HEK293 Cells , 1997 .
[158] G. Lamb,et al. Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia. , 1997, Biophysical journal.
[159] D. Maclennan,et al. Single-channel properties of the recombinant skeletal muscle Ca2+ release channel (ryanodine receptor). , 1997, Biophysical journal.
[160] T. Murayama,et al. Characterization of Type 3 Ryanodine Receptor (RyR3) of Sarcoplasmic Reticulum from Rabbit Skeletal Muscles* , 1997, The Journal of Biological Chemistry.
[161] Yvonne M. Kobayashi,et al. Complex Formation between Junctin, Triadin, Calsequestrin, and the Ryanodine Receptor , 1997, The Journal of Biological Chemistry.
[162] R. Nixon,et al. Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease , 1997, Brain Research.
[163] M. Mattson,et al. Alzheimer’s Presenilin Mutation Sensitizes Neural Cells to Apoptosis Induced by Trophic Factor Withdrawal and Amyloid β-Peptide: Involvement of Calcium and Oxyradicals , 1997, The Journal of Neuroscience.
[164] A. Dulhunty,et al. Magnesium Inhibition of Ryanodine-Receptor Calcium Channels: Evidence for Two Independent Mechanisms , 1997, The Journal of Membrane Biology.
[165] D. Selkoe,et al. Caffeine stimulates amyloid beta-peptide release from beta-amyloid precursor protein-transfected HEK293 cells. , 1997, Journal of neurochemistry.
[166] Huafeng Wei,et al. Dantrolene Is Cytoprotective in Two Models of Neuronal Cell Death , 1996, Journal of neurochemistry.
[167] K. Kawasaki,et al. Protein kinase inhibitor attenuates apoptotic cell death induced by amyloid β protein in culture of the rat cerebral cortex , 1996, Neuroscience Letters.
[168] M. Mattson,et al. Activation of K+ channels and suppression of neuronal activity by secreted β-amyloid-precursor protein , 1996, Nature.
[169] F. Checler. Processing of the β‐Amyloid Precursor Protein and Its Regulation in Alzheimer's Disease , 1995 .
[170] M E Greenberg,et al. Calcium signaling in neurons: molecular mechanisms and cellular consequences. , 1995, Science.
[171] S. Mammarella,et al. The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues , 1995, The Journal of cell biology.
[172] F. Checler. Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease. , 1995, Journal of neurochemistry.
[173] P. Greengard,et al. Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[174] D. Selkoe,et al. Calcium ionophore increases amyloid beta peptide production by cultured cells. , 1994, Biochemistry.
[175] K. Oka,et al. Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[176] A. Verkhratsky,et al. Caffeine-induced calcium release from internal stores in cultured rat sensory neurons , 1993, Neuroscience.
[177] S. Younkin,et al. Production of Amyloid β Protein from Normal Amyloid β‐Protein Precursor (βAPP) and the Mutated βAPPS Linked to Familial Alzheimer's Disease a , 1993 .
[178] E. Rojas,et al. Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[179] S. Younkin,et al. Production of amyloid beta protein from normal amyloid beta-protein precursor (beta APP) and the mutated beta APPS linked to familial Alzheimer's disease. , 1993, Annals of the New York Academy of Sciences.
[180] S. B. Kater,et al. Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones. , 1993, Science.
[181] G. Collingridge,et al. Thapsigargin blocks the induction of long-term potentiation in rat hippocampal slices , 1992, Neuroscience Letters.
[182] M. Mattson,et al. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[183] A. Schousboe,et al. Dantrolene Prevents Glutamate Cytotoxicity and Ca2+ Release from Intracellular Stores in Cultured Cerebral Cortical Neurons , 1991, Journal of neurochemistry.
[184] G. Tollefson. Short-term effects of the calcium channel blocker nimodipine (Bay-e-9736) in the management of primary degenerative dementia , 1990, Biological Psychiatry.
[185] Z. Khachaturian. Introduction and Overview , 1989, Annals of the New York Academy of Sciences.
[186] L. Farrer,et al. Molecular Genetics of Familial Alzheimer's Disease , 1989, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.
[187] M. Dailey,et al. Dynamics of the endoplasmic reticulum and other membranous organelles in growth cones of cultured neurons , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[188] I. Módy,et al. Dantrolene-Na (Dantrium) blocks induction of long-term potentiation in hippocampal slices , 1989, Neuroscience Letters.
[189] C. Cotman,et al. Calcium, membranes, aging, and Alzheimer's disease , 1989 .
[190] G. Meissner,et al. Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum. , 1986, The Journal of biological chemistry.
[191] M. L. Horne,et al. Dantrolene in Human Malignant Hyperthermia A Multicenter Study , 1982 .
[192] M. L. Horne,et al. Dantrolene in human malignant hyperthermia. , 1982, Anesthesiology.
[193] R. Bickerton,et al. 1-[(5-arylfurfurylidene)amino]hydantoins. A new class of muscle relaxants. , 1967, Journal of medicinal chemistry.