The use of multiple tools for teaching medical biochemistry.

In this work, we describe the use of several strategies employing the philosophies of active learning and problem-based learning (PBL) that may be used to improve the teaching of metabolic biochemistry to medical and nutritional undergraduate students. The main activities are as follows: 1) a seminar/poster system in a mini-congress format (using topics of applied biochemistry); 2) a true/false applied biochemistry exam (written by peer tutors); 3) a 9-h exam on metabolism (based in real publications); 4) the Advanced Biochemistry course (directed to peer tutors, where students learn how to read and criticize real medical papers); 5) experiments about nutrition and metabolism, using students as volunteers, and about free radicals (real science for students); 6) the BioBio blog (taking advantage of the "web age," this enhances out of class exchanges of information between the professor, students, and peer tutors); 7) student lectures on public health issues and metabolic disorders directed to the community and lay people; and 8) the BioBio quiz show. The main objective of these activities is to provide students with a more practical and interesting approach to biochemistry, such as the application of theoretical knowledge to real situations (diseases, experiments, media information, and scientific discoveries). In addition, we emphasize the importance of peer tutor activities for optimized learning of both students and peer tutors, the importance of a closer interaction between students and teaching staff, and the necessity to initiate students precociously in two broad fields of medical activity: "real" basic science and contact with the public (also helping students--future doctors and nutritionists--to be able to communicate with lay people). Most activities were evaluated by the students through written questionnaires and informal conversations, along various semesters, indicating good acceptance and approval of these methods. Good student scores in the biochemistry exams and seminars indicated that these activities are also working as valid educational tools.

[1]  Y. K. Nóbrega,et al.  Pizza and pasta help students learn metabolism. , 2006, Advances in physiology education.

[2]  P. Gluckman,et al.  Sedentary behavior during postnatal life is determined by the prenatal environment and exacerbated by postnatal hypercaloric nutrition. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

[3]  S. DiCarlo,et al.  Who wants to be a physician? An educational tool for reviewing pulmonary physiology. , 2000, Advances in physiology education.

[4]  G. Matheson,et al.  Effects on regional brain metabolism of high-altitude hypoxia: a study of six US marines. , 1999, American Journal of Physiology. Regulatory Integrative and Comparative Physiology.

[5]  J. Wardle,et al.  Positive affect and health-related neuroendocrine, cardiovascular, and inflammatory processes. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[6]  S. DiCarlo,et al.  "Survivor" torches "Who Wants to Be a Physician?" in the educational games ratings war. , 2002, Advances in physiology education.

[7]  Harvey F Lodish,et al.  Points of view: lectures: can't learn with them, can't learn without them. , 2004, Cell biology education.

[8]  Robert H. Glew,et al.  The problem with problem‐based medical education: Promises not kept , 2003 .

[9]  Daniel R. Anderson,et al.  On the road to obesity: Television viewing increases intake of high-density foods , 2006, Physiology & Behavior.

[10]  Andrew R Coggan,et al.  Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. , 2004, The New England journal of medicine.

[11]  R. Epstein,et al.  Learning from the problems of problem-based learning , 2004, BMC medical education.

[12]  The Relevance of student seminars on clinically related subjects in a biochemistry course for medical and nutrition students , 2002 .

[13]  S. DiCarlo,et al.  First-year medical students prefer multiple learning styles. , 2006, Advances in physiology education.

[14]  Patangi K. Rangachari,et al.  Beyond facilitation: The active tutor in a problem‐based course , 1996 .

[15]  D. D’Alessio,et al.  Protein, fat, and carbohydrate requirements during starvation: anaplerosis and cataplerosis. , 1998, The American journal of clinical nutrition.

[16]  Marcelo Hermes-Lima,et al.  Advanced Biochemistry Course teach students how to make and criticize science , 2006 .

[17]  S. Jackson,et al.  Exercise, free radicals, and lipid peroxidation in type 1 diabetes mellitus. , 2002, Free radical biology & medicine.

[18]  G. Brosvic,et al.  Students Prefer the Immediate Feedback Assessment Technique , 2002, Psychological reports.

[19]  S. DiCarlo,et al.  Peer instruction enhanced meaningful learning: ability to solve novel problems. , 2005, Advances in physiology education.

[20]  D A Lake,et al.  Peer tutoring improves student performance in an advanced physiology course. , 1999, The American journal of physiology.

[21]  S. Klein,et al.  Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[22]  M. Hermes-Lima Oxygen in Biology and Biochemistry: Role of Free Radicals , 2005 .

[23]  H. Schulman,et al.  Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions. , 1999, Biochimica et biophysica acta.

[24]  C. Kahn,et al.  Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4. , 2001, The Journal of clinical investigation.

[25]  D. Allison,et al.  Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. , 2001, American journal of physiology. Endocrinology and metabolism.

[26]  K. Storey Functional metabolism : regulation and adaptation , 2005 .

[27]  Steve Wheeler,et al.  Wikis, blogs and podcasts: a new generation of Web-based tools for virtual collaborative clinical practice and education , 2006, BMC medical education.

[28]  Deborah Allen,et al.  Approaches to cell biology teaching: questions about questions. , 2002, Cell biology education.

[29]  B. Hodges,et al.  Student feedback in problem based learning: a survey of 103 final year students across five Ontario medical schools , 2001, Medical education.

[30]  Cees P M van der Vleuten,et al.  General competencies of problem‐based learning (PBL) and non‐PBL graduates , 2005, Medical education.

[31]  J. Michael Where's the evidence that active learning works? , 2006, Advances in physiology education.

[32]  Marcelo Hermes-Lima,et al.  A 9-hour biochemistry exam. An iron man competition or a good way of evaluating undergraduate students? , 2005 .

[33]  References , 1971 .

[34]  P K Rangachari,et al.  A checklist to help students analyze published articles in basic medical sciences. , 1995, The American journal of physiology.