Fatty acids in cancer: Metabolic functions and potential treatment
暂无分享,去创建一个
Kefei Yuan | Guoteng Qiu | Chuang Jiang | Tengda Huang | Shuai Xue | Ao Du | Zhen Wang | G. Qiu
[1] T. Katagiri,et al. Blue light induces apoptosis and autophagy by promoting ROS‐mediated mitochondrial dysfunction in synovial sarcoma , 2023, Cancer medicine.
[2] Ping-Tzu Chen,et al. Tetrahydrocurcumin regulates the tumor immune microenvironment to inhibit breast cancer proliferation and metastasis via the CYP1A1/NF-κB signaling pathway , 2023, Cancer Cell International.
[3] Y. Ke,et al. Molecular mechanisms on how FABP5 inhibitors promote apoptosis‐induction sensitivity of prostate cancer cells , 2023, Cell biology international.
[4] S. Tsai,et al. Gold Nanoparticles Enhancing Generation of ROS for Cs-137 Radiotherapy , 2022, Nanoscale research letters.
[5] Juan Wang,et al. c-Jun phosphorylated by JNK is required for protecting Gli2 from proteasomal-ubiquitin degradation by PGE2-JNK signaling axis. , 2022, Biochimica et biophysica acta. Molecular cell research.
[6] Michael R Hamblin,et al. Tumor-derived exosomal non-coding RNAs as diagnostic biomarkers in cancer , 2022, Cellular and Molecular Life Sciences.
[7] S. Welford,et al. Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets , 2022, Nature Reviews Urology.
[8] S. Benitah,et al. The role of lipids in cancer progression and metastasis. , 2022, Cell metabolism.
[9] A. Giannoudis,et al. The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach , 2022, Scientific Reports.
[10] M. Colombo,et al. SCD5-dependent inhibition of SPARC secretion hampers metastatic spreading and favors host immunity in a TNBC murine model , 2022, Oncogene.
[11] Jilin Li,et al. Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein , 2022, Cancer biology & therapy.
[12] Chun-Bing Chen,et al. Cancer-Derived Extracellular Vesicles as Biomarkers for Cutaneous Squamous Cell Carcinoma: A Systematic Review , 2022, Cancers.
[13] M. Kolonin,et al. Fatty acid translocase: a culprit of lipid metabolism dysfunction in disease , 2022, Immunometabolism (Cobham (Surrey, England)).
[14] C. Ishioka,et al. Inhibition of stearoyl-CoA desaturase 1 (SCD1) enhances the antitumor T cell response through regulating β-catenin signaling in cancer cells and ER stress in T cells and synergizes with anti-PD-1 antibody , 2022, Journal for ImmunoTherapy of Cancer.
[15] Jieqing Li,et al. Prevention of taxane-associated acute pain syndrome with etoricoxib for patients with breast cancer: A phase II randomised trial. , 2022, European journal of cancer.
[16] C. Garrido,et al. Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers , 2022, Molecular oncology.
[17] Hui Zhang,et al. ELOVL2 restrains cell proliferation, migration, and invasion of prostate cancer via regulation of the tumor suppressor INPP4B. , 2022, Cellular signalling.
[18] Wei Wang,et al. FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis , 2022, Cell Death & Disease.
[19] D. Hong,et al. Dietary influences on symptomatic and non-symptomatic toxicities during cancer treatment: A narrative review. , 2022, Cancer treatment reviews.
[20] F. Finkernagel,et al. Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures , 2022, Molecular oncology.
[21] Peng-Ju Chen,et al. Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents , 2022, Journal of enzyme inhibition and medicinal chemistry.
[22] Alissa M. Weaver,et al. Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement. , 2022, Endocrine reviews.
[23] H. Pan,et al. Highly Purified Eicosapentaenoic Acid Alleviates the Inflammatory Response and Oxidative Stress in Macrophages during Atherosclerosis via the miR-1a-3p/sFRP1/Wnt/PCP-JNK Pathway , 2022, Oxidative medicine and cellular longevity.
[24] Aijun Wang,et al. Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion , 2022, Nature Communications.
[25] Casie Kubota,et al. Targeting stearoyl-CoA desaturase in solid tumors. , 2022, Cancer research.
[26] Jibo He,et al. Acetyl-CoA Carboxylases and Diseases , 2022, Frontiers in Oncology.
[27] S. Pakrashi,et al. Quercetin Attenuates Copper-Induced Apoptotic Cell Death and Endoplasmic Reticulum Stress in SH-SY5Y Cells by Autophagic Modulation , 2022, Biological Trace Element Research.
[28] Q. Ye,et al. MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation , 2022, Cancer & metabolism.
[29] H. Nishiyama,et al. ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma , 2021, Oncology reports.
[30] S. Yuan,et al. Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma , 2021, Acta pharmaceutica Sinica. B.
[31] A. Bode,et al. Prostaglandin Pathways: Opportunities for Cancer Prevention and Therapy , 2021, Cancer research.
[32] Hui Zheng,et al. Differentially Expressed Genes in Clear Cell Renal Cell Carcinoma as a Potential Marker for Prognostic and Immune Signatures , 2021, Frontiers in Oncology.
[33] M. Tavakoli-Yaraki,et al. 15-Lipoxygenase and its metabolites in the pathogenesis of breast cancer: A double-edged sword , 2021, Lipids in health and disease.
[34] I. Fleming,et al. Cytochrome P450-derived fatty acid epoxides and diols in angiogenesis and stem cell biology. , 2021, Pharmacology & therapeutics.
[35] Jianbo Xiao,et al. Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease , 2021, International journal of molecular sciences.
[36] M. V. Vander Heiden,et al. Low glycaemic diets alter lipid metabolism to influence tumour growth , 2021, Nature.
[37] H. You,et al. Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation , 2021, Experimental & Molecular Medicine.
[38] R. DuBois,et al. Cyclooxygenases and Prostaglandins in Tumor Immunology and Microenvironment of Gastrointestinal Cancer. , 2021, Gastroenterology.
[39] Yuan Fang,et al. Integration of glucose and cardiolipin anabolism confers radiation resistance of HCC , 2021, Hepatology.
[40] Chih-Yu Chen,et al. Increased lipogenesis is critical for self‐renewal and growth of breast cancer stem cells: Impact of omega‐3 fatty acids , 2021, Stem cells.
[41] Sajeli Begum Ahil,et al. Review on target domains and natural compound‐based inhibitors of fatty acid synthase for anticancer drug discovery , 2021 .
[42] L. Butler,et al. Tumour fatty acid metabolism in the context of therapy resistance and obesity , 2021, Nature Reviews Cancer.
[43] Jared L. Johnson,et al. Dietary fructose improves intestinal cell survival and nutrient absorption , 2021, Nature.
[44] Á. Lanas,et al. Platelets induce free and phospholipid-esterified 12-hydroxyeicosatetraenoic acid generation in colon cancer cells by delivering 12-lipoxygenase , 2021, Journal of lipid research.
[45] C. Denkert,et al. Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer: The REACT Randomized Clinical Trial. , 2021, JAMA oncology.
[46] C. Pareek,et al. Effects of Dietary n–3 and n–6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis , 2021, International journal of molecular sciences.
[47] A. Kozubík,et al. Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells , 2021, International journal of molecular sciences.
[48] S. Denmeade,et al. Fatty Acid Synthesis in Prostate Cancer: Vulnerability or Epiphenomenon? , 2021, Cancer Research.
[49] Zhihua Wen,et al. RAD001 targeted HUVECs reverses 12‐lipoxygenase‐induced angiogenesis in oesophageal squamous cell carcinoma , 2021, Journal of cellular and molecular medicine.
[50] O. Feron,et al. Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects. , 2021, Cell metabolism.
[51] J. Prieto,et al. In Vitro Effects of Selective COX and LOX Inhibitors and Their Combinations with Antineoplastic Drugs in the Mouse Melanoma Cell Line B16F10 , 2021, International journal of molecular sciences.
[52] Chen-Yu Zhang,et al. Long Noncoding RNA CTD-2245E15.3 Promotes Anabolic Enzymes ACC1 and PC to Support Non–Small Cell Lung Cancer Growth , 2021, Cancer Research.
[53] G. Barceló-Coblijn,et al. Fatty Acid Unsaturation Degree of Plasma Exosomes in Colorectal Cancer Patients: A Promising Biomarker , 2021, International journal of molecular sciences.
[54] J. Meyerhardt,et al. Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial. , 2021, JAMA.
[55] A. Brenner,et al. First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors , 2021, EClinicalMedicine.
[56] K. Koike,et al. Lipid Metabolism in Oncology: Why It Matters, How to Research, and How to Treat , 2021, Cancers.
[57] L. Butler,et al. The diversity and breadth of cancer cell fatty acid metabolism , 2021, Cancer & metabolism.
[58] L. Qin,et al. Lipid metabolism in cancer progression and therapeutic strategies , 2020, MedComm.
[59] J. Kench,et al. Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition , 2020, Cancer Research.
[60] Ryan D. Clay,et al. PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction , 2020, Cell reports.
[61] Hongyang Wang,et al. ATP-citrate lyase regulates stemness and metastasis in hepatocellular carcinoma via the Wnt/β-catenin signaling pathway. , 2020, Hepatobiliary & pancreatic diseases international : HBPD INT.
[62] S. Rockson,et al. Leukotrienes in Tumor-Associated Inflammation , 2020, Frontiers in Pharmacology.
[63] D. Klionsky,et al. Ferroptosis: machinery and regulation , 2020, Autophagy.
[64] M. Rafat,et al. Lipids in the tumor microenvironment: From cancer progression to treatment. , 2020, Progress in lipid research.
[65] M. Althubiti,et al. Evaluation of the Diagnostic and Predicative Values of 8-Iso-Prostaglandin F2α as a Biomarker of Breast Cancer , 2020, Oncology Research and Treatment.
[66] Galina A. Erikson,et al. Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. , 2020, Gastroenterology.
[67] M. Loda,et al. Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention. , 2020, Advanced drug delivery reviews.
[68] C. Muller,et al. Drilling for Oil: Tumor-Surrounding Adipocytes Fueling Cancer. , 2020, Trends in cancer.
[69] Ying-bo Li,et al. Eicosapentaenoic acid’s metabolism of 15-LOX-1 promotes the expression of miR-101 thus inhibits Cox2 pathway in colon cancer , 2020, OncoTargets and therapy.
[70] B. Stockwell,et al. Emerging Mechanisms and Disease Relevance of Ferroptosis. , 2020, Trends in cell biology.
[71] K. Vousden,et al. Dietary Approaches to Cancer Therapy. , 2020, Cancer cell.
[72] B. Faubert,et al. Metabolic reprogramming and cancer progression , 2020, Science.
[73] Yi-chun Chen,et al. FABP7 is a potential biomarker to predict response to neoadjuvant chemotherapy for breast cancer , 2020, Cancer Cell International.
[74] J. Ajani,et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression , 2020, Cell Research.
[75] B. Stockwell,et al. Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers. , 2020, ACS chemical biology.
[76] M. L. Curri,et al. Exosomes for Diagnosis and Therapy in Gastrointestinal Cancers , 2020, International journal of molecular sciences.
[77] E. Yilmaz,et al. Untargeted Multi-Omic Analysis of Colorectal Cancer-Specific Exosomes Reveals Joint Pathways of Colorectal Cancer in both Clinical Samples and Cell Culture. , 2020, Cancer letters.
[78] S. Fan,et al. High COX‐2 expression in cancer‐associated fibiroblasts contributes to poor survival and promotes migration and invasiveness in nasopharyngeal carcinoma , 2019, Molecular carcinogenesis.
[79] H. Tsukamoto,et al. Stearoyl-CoA desaturase and tumorigenesis. , 2019, Chemico-biological interactions.
[80] A. C. Gasparovic,et al. Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets. , 2019, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[81] S. Nowicki,et al. GPR75 receptor mediates 20-HETE-signaling and metastatic features of androgen-insensitive prostate cancer cells. , 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.
[82] Siwei Wang,et al. Four transcription profile–based models identify novel prognostic signatures in oesophageal cancer , 2019, Journal of cellular and molecular medicine.
[83] L. Trotman,et al. Docetaxel/cabazitaxel and fatty acid binding protein 5 inhibitors produce synergistic inhibition of prostate cancer growth , 2019, The Prostate.
[84] Xi Zhang,et al. Identification of hub genes and key pathways associated with the progression of gynecological cancer , 2019, Oncology letters.
[85] Jeng-Jong Hwang,et al. Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway , 2019, Scientific Reports.
[86] Li Zhao,et al. ACLY facilitates colon cancer cell metastasis by CTNNB1 , 2019, Journal of Experimental & Clinical Cancer Research.
[87] Wei Zhao,et al. Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors. , 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[88] A. Joubert,et al. Warburg effect and its role in tumourigenesis , 2019, Archives of Pharmacal Research.
[89] T. Curran,et al. Leukotriene Synthesis Is Critical for Medulloblastoma Progression , 2019, Clinical Cancer Research.
[90] M. Matin,et al. Stylosin and some of its synthetic derivatives induce apoptosis in prostate cancer cells as 15-lipoxygenase enzyme inhibitors , 2019, Naunyn-Schmiedeberg's Archives of Pharmacology.
[91] C. Thompson,et al. Metabolic regulation of cell growth and proliferation , 2019, Nature Reviews Molecular Cell Biology.
[92] J. Swinnen,et al. Lipid metabolism in cancer cells under metabolic stress , 2019, British Journal of Cancer.
[93] G. Wang,et al. Inhibition of LTA4H by bestatin in human and mouse colorectal cancer , 2019, EBioMedicine.
[94] Ben S. Wittner,et al. COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis , 2019, Proceedings of the National Academy of Sciences.
[95] Zhenggang Zhu,et al. CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway , 2019, Journal of experimental & clinical cancer research : CR.
[96] B. Faubert,et al. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity , 2019, Nature.
[97] P. Muti,et al. Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma. , 2019, Cell metabolism.
[98] Zhe Zhang,et al. Inhibition of stearoyl CoA desaturase‐1 activity suppresses tumour progression and improves prognosis in human bladder cancer , 2018, Journal of cellular and molecular medicine.
[99] F. Torti,et al. Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death. , 2019, Cancer research.
[100] M. Touvier,et al. Saturated, mono- and polyunsaturated fatty acid intake and cancer risk: results from the French prospective cohort NutriNet-Santé , 2019, European Journal of Nutrition.
[101] L. Fattore,et al. Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma , 2018, Journal of experimental & clinical cancer research : CR.
[102] K. Ghaedi,et al. Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers. , 2018, Gene.
[103] S. Braig. Chemical genetics in tumor lipogenesis. , 2018, Biotechnology advances.
[104] A. Colquhoun,et al. Eicosanoids and cancer , 2018, Clinics.
[105] G. Ren,et al. Utilization of adipocyte-derived lipids and enhanced intracellular trafficking of fatty acids contribute to breast cancer progression , 2018, Cell Communication and Signaling.
[106] S. Chien,et al. Suspension state promotes metastasis of breast cancer cells by up-regulating cyclooxygenase-2 , 2018, Theranostics.
[107] I. Fleming,et al. Angiogenesis and vascular stability in eicosanoids and cancer , 2018, Cancer and Metastasis Reviews.
[108] D. Xie,et al. FABP4 suppresses proliferation and invasion of hepatocellular carcinoma cells and predicts a poor prognosis for hepatocellular carcinoma , 2018, Cancer medicine.
[109] Giuseppe Infusini,et al. Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine , 2018, Proteomics. Clinical applications.
[110] A. Shiau,et al. Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression , 2018, Scientific Reports.
[111] N. deSouza,et al. The effect of FASN inhibition on the growth and metabolism of a cisplatin‐resistant ovarian carcinoma model , 2018, International journal of cancer.
[112] Yu-Ying He,et al. Knockdown delta-5-desaturase in breast cancer cells that overexpress COX-2 results in inhibition of growth, migration and invasion via a dihomo-γ-linolenic acid peroxidation dependent mechanism , 2018, BMC Cancer.
[113] J. Onuchic,et al. Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy , 2018, Theranostics.
[114] F. Berrino,et al. Diet and supplements in cancer prevention and treatment: Clinical evidences and future perspectives. , 2018, Critical reviews in oncology/hematology.
[115] Hua Yu,et al. JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance. , 2018, Cell metabolism.
[116] T. Cotter,et al. Seminars in Cell & Developmental Biology , 2018 .
[117] Jung-Hye Choi,et al. Iloprost, a prostacyclin analog, inhibits the invasion of ovarian cancer cells by downregulating matrix metallopeptidase-2 (MMP-2) through the IP-dependent pathway. , 2018, Prostaglandins & other lipid mediators.
[118] M. Stockler,et al. A distinct plasma lipid signature associated with poor prognosis in castration‐resistant prostate cancer , 2017, International Journal of Cancer.
[119] Yu Bai,et al. A plasma lipidomics strategy reveals perturbed lipid metabolic pathways and potential lipid biomarkers of human colorectal cancer. , 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[120] V. Jala,et al. The yin and yang of leukotriene B4 mediated inflammation in cancer. , 2017, Seminars in immunology.
[121] J. Haeggström,et al. Biosynthesis of leukotriene B4. , 2017, Seminars in immunology.
[122] J. Menéndez,et al. Fatty acid synthase (FASN) as a therapeutic target in breast cancer , 2017, Expert opinion on therapeutic targets.
[123] Yinsong Wang,et al. Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis , 2017, Journal of experimental & clinical cancer research : CR.
[124] Pengyuan Yang,et al. Functional lipidomics: Palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism , 2017, Hepatology.
[125] E. Cuyás,et al. Clinical and therapeutic relevance of the metabolic oncogene fatty acid synthase in HER2+ breast cancer. , 2017, Histology and histopathology.
[126] R. Chapkin,et al. Dietary fat and fiber interactively modulate apoptosis and mitochondrial bioenergetic profiles in mouse colon in a site-specific manner , 2017, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.
[127] Stuart L. Schreiber,et al. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition , 2017, Nature.
[128] O. Sansom,et al. Modulating the therapeutic response of tumours to dietary serine and glycine starvation , 2017, Nature.
[129] Yu Xia,et al. Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells. , 2017, Cell stem cell.
[130] Peixuan Guo,et al. Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells , 2017, Redox biology.
[131] A. Avan,et al. Circulating exosomes and exosomal microRNAs as biomarkers in gastrointestinal cancer , 2016, Cancer Gene Therapy.
[132] Camille Stephan-Otto Attolini,et al. Targeting metastasis-initiating cells through the fatty acid receptor CD36 , 2016, Nature.
[133] B. Patil,et al. Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk , 2016, Cell Death & Disease.
[134] M. Kreft,et al. Comparative lipidomic study of urothelial cancer models: association with urothelial cancer cell invasiveness. , 2016, Molecular bioSystems.
[135] M. Johansson,et al. Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis. , 2016, Cancer research.
[136] B. Stockwell,et al. Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis , 2016, Proceedings of the National Academy of Sciences.
[137] B. Guo,et al. Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs. , 2016, Free radical biology & medicine.
[138] Yuanying Chen,et al. Fatty acid metabolism and cancer development , 2016 .
[139] E. White,et al. Mitochondria and Cancer. , 2016, Molecular cell.
[140] Yu-Huei Liu,et al. Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma , 2016, Oncotarget.
[141] N. Casals,et al. Carnitine palmitoyltransferase 1C: From cognition to cancer. , 2016, Progress in lipid research.
[142] A. Houston,et al. Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets? , 2015, British journal of pharmacology.
[143] L. Roberts,et al. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma , 2015, Scientific Reports.
[144] J. Käs,et al. Cell membrane softening in human breast and cervical cancer cells , 2015 .
[145] N. Youssef,et al. Combined use of COX-1 and VEGF immunohistochemistry refines the histopathologic prognosis of renal cell carcinoma. , 2015, International journal of clinical and experimental pathology.
[146] Yu-Jen Chao,et al. Polyunsaturated fatty acids incorporation into cardiolipin in H9c2 cardiac myoblast. , 2015, The Journal of nutritional biochemistry.
[147] F. Mottaghy,et al. Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer , 2015, Journal of Translational Medicine.
[148] Feng Wang,et al. Four types of fatty acids exert differential impact on pancreatic cancer growth. , 2015, Cancer letters.
[149] U. Das,et al. Growth Inhibitory Effect of Polyunsaturated Fatty Acids (PUFAs) on Colon Cancer Cells via Their Growth Inhibitory Metabolites and Fatty Acid Composition Changes , 2015, PloS one.
[150] X. Ren,et al. Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth , 2015, Breast Cancer Research.
[151] Xiaolong Wei,et al. Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer , 2014, BMC Cancer.
[152] Leah Rider,et al. Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer , 2014, Molecular Cancer Therapeutics.
[153] W. Mustain,et al. Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer. , 2014, Carcinogenesis.
[154] Mohamed Abdelwahab Alassal,et al. Cytochrome P450-isoenzyme 1A1 in susceptibility to tobacco-related lung cancer , 2014, Asian cardiovascular & thoracic annals.
[155] M. Imoto,et al. 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation , 2014, Cancer science.
[156] R. Pink,et al. Routes and mechanisms of extracellular vesicle uptake , 2014, Journal of extracellular vesicles.
[157] Hua Li,et al. Mechanism of fatty acid synthase in drug tolerance related to epithelial-mesenchymal transition of breast cancer. , 2014, Asian Pacific journal of cancer prevention : APJCP.
[158] Ajay Kumar,et al. Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: implication of reconstituted tumor microenvironment and multidrug resistance phenotype. , 2014, Biochimica et biophysica acta.
[159] Robert V Farese,et al. Cellular fatty acid metabolism and cancer. , 2013, Cell metabolism.
[160] T. Balla,et al. Phosphoinositides: tiny lipids with giant impact on cell regulation. , 2013, Physiological reviews.
[161] R. Matsunuma,et al. Human Breast Cancer Tissues Contain Abundant Phosphatidylcholine(36∶1) with High Stearoyl-CoA Desaturase-1 Expression , 2013, PloS one.
[162] S. Hwang,et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis , 2013, Proceedings of the National Academy of Sciences.
[163] H. Hurwitz,et al. A phase I study of ABT-510 plus bevacizumab in advanced solid tumors , 2013, Cancer medicine.
[164] R. Coletta,et al. The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas , 2012, British Journal of Cancer.
[165] Ximing Xu,et al. Inhibition of 12-lipoxygenase reduces proliferation and induces apoptosis of hepatocellular carcinoma cells in vitro and in vivo. , 2012, Hepatobiliary & pancreatic diseases international : HBPD INT.
[166] R. Deberardinis,et al. Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us? , 2012, Cell.
[167] Vito Pistoia,et al. Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy , 2012, Science Translational Medicine.
[168] A. Kihara,et al. Biochemical characterization of the very long‐chain fatty acid elongase ELOVL7 , 2011, FEBS letters.
[169] J. Rolin,et al. Effects of Lysophospholipids on Tumor Microenvironment , 2011, Cancer Microenvironment.
[170] E. Schuetz,et al. CYP3A4 Mediates Growth of Estrogen Receptor-positive Breast Cancer Cells in Part by Inducing Nuclear Translocation of Phospho-Stat3 through Biosynthesis of (±)-14,15-Epoxyeicosatrienoic Acid (EET)* , 2011, The Journal of Biological Chemistry.
[171] Carol L. Williams,et al. Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists , 2010, Cancer science.
[172] Sebastian Munck,et al. De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation. , 2010, Cancer research.
[173] S. Heys,et al. Profiling the expression of cytochrome P450 in breast cancer , 2010, Histopathology.
[174] T. Oda,et al. Fatty acid synthase inhibitor cerulenin suppresses liver metastasis of colon cancer in mice , 2010, Cancer science.
[175] G. Pond,et al. A phase III randomized trial of the timing of meloxicam with iodine-125 prostate brachytherapy. , 2010, International journal of radiation oncology, biology, physics.
[176] R. DuBois,et al. Eicosanoids and cancer , 2010, Nature Reviews Cancer.
[177] K. Kaluarachchi,et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. , 2010, The Journal of clinical investigation.
[178] Sreeparna Banerjee,et al. 15‐Lipoxygenase‐1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT‐116 and HT‐29 , 2009, Cancer science.
[179] N. Yonemitsu,et al. 5-lipoxygenase pathway promotes cell proliferation in human glioma cell lines. , 2009, Clinical Neuropathology.
[180] Yusuke Nakamura,et al. Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism. , 2009, Cancer research.
[181] S. Nonogaki,et al. Leukotriene B4 Creates a Favorable Microenvironment for Murine Melanoma Growth , 2009, Molecular Cancer Research.
[182] Zhi Wang,et al. Topical chemoprevention of skin cancer in mice, using combined inhibitors of 5-lipoxygenase and cyclo-oxygenase-2 , 2009, The Journal of Laryngology & Otology.
[183] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[184] Heather R. Roberts,et al. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. , 2009, Carcinogenesis.
[185] D. Jump. Mammalian fatty acid elongases. , 2009, Methods in molecular biology.
[186] A. Horiguchi,et al. Pharmacological inhibitor of fatty acid synthase suppresses growth and invasiveness of renal cancer cells. , 2008, The Journal of urology.
[187] Carl Morrison,et al. Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[188] J. Swinnen,et al. Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. , 2007, Cancer research.
[189] A. C. Williams,et al. Prostaglandin F2α stimulates motility and invasion in colorectal tumor cells , 2007 .
[190] M. Hersberger,et al. The two faces of the 15-lipoxygenase in atherosclerosis. , 2007, Prostaglandins, leukotrienes, and essential fatty acids.
[191] M. Kreutzer,et al. Specific components of prostanoid-signaling pathways are present in non-small cell lung cancer cells. , 2007, Oncology reports.
[192] D. Chalbos,et al. Increased expression of fatty acid synthase and progesterone receptor in early steps of human mammary carcinogenesis , 2007, International journal of cancer.
[193] L. Dwyer-Nield,et al. Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis. , 2006, Anticancer research.
[194] R. Kerbel,et al. Metronomic Low-Dose Chemotherapy Boosts CD95-Dependent Antiangiogenic Effect of the Thrombospondin Peptide ABT-510: A Complementation Antiangiogenic Strategy , 2005, Clinical Cancer Research.
[195] R. DuBois,et al. PROSTAGLANDINS AND CANCER , 2005, Gut.
[196] P. Stehle,et al. Preoperative Oral Supplementation with Long-Chain Ω-3 Fatty Acids Beneficially Alters Phospholipid Fatty Acid Patterns in Liver, Gut Mucosa, and Tumor Tissue. , 2005, JPEN. Journal of parenteral and enteral nutrition.
[197] D. Zeldin,et al. Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. , 2005, Cancer research.
[198] R. DuBois,et al. The role of prostaglandins and other eicosanoids in the gastrointestinal tract. , 2005, Gastroenterology.
[199] B. Wong,et al. Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke. , 2005, Carcinogenesis.
[200] V. Baracos,et al. n-3 Polyunsaturated fatty acids throughout the cancer trajectory: influence on disease incidence, progression, response to therapy and cancer-associated cachexia , 2004, Nutrition Research Reviews.
[201] D. Beer,et al. Overexpression of 5-Lipoxygenase in Rat and Human Esophageal Adenocarcinoma and Inhibitory Effects of Zileuton and Celecoxib on Carcinogenesis , 2004, Clinical Cancer Research.
[202] H. Guski,et al. Effects of Celebrex and Zyflo on liver metastasis and lipidperoxidation in pancreatic cancer in Syrian hamsters , 2001, Clinical & Experimental Metastasis.
[203] G. Landberg,et al. Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas. , 2003, Gastroenterology.
[204] R. Carroll,et al. Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. , 2002, Carcinogenesis.
[205] T. Eling,et al. Opposing Effects of 15-Lipoxygenase-1 and -2 Metabolites on MAPK Signaling in Prostate , 2002, The Journal of Biological Chemistry.
[206] M. Sentjurc,et al. Cell membrane fluidity and prognosis of lung cancer. , 2002, The Annals of thoracic surgery.
[207] J. Lupton,et al. Dietary n−3 PUFA alter colonocyte mitochondrial membrane composition and function , 2002, Lipids.
[208] J. Masferrer,et al. Selective inhibition of Δ-6 desaturase impedes intestinal tumorigenesis , 2002 .
[209] D. Grignon,et al. Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer. , 1995, Urology.
[210] A. Mantovani,et al. Membrane fluidity affects tumor‐cell motility, invasion and lung‐colonizing potential , 1989, International journal of cancer.
[211] J. Bockaert,et al. NMDA receptors activate the arachidonic acid cascade system in striatal neurons , 1988, Nature.
[212] A A Spector,et al. Membrane lipid composition and cellular function. , 1985, Journal of lipid research.