PCA based polarized fluorescence study for detecting human cervical dysplasia

The two highest principal components of fluorescence spectra in visible region obtained, using Xenon lamp as an excitation source of normal and dysplastic human cervical tissues are analyzed using scatter plots and probability density functions. These yield significant differences between the tissue types.

[1]  Asima Pradhan,et al.  Polarized fluorescence study in human cervical tissue: change in autofluorescence through different excitation wavelengths , 2010, BiOS.

[2]  Asima Pradhan,et al.  Characterizing breast cancer tissues through the spectral correlation properties of polarized fluorescence. , 2008, Journal of biomedical optics.

[3]  R Richards-Kortum,et al.  Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: modeling, measurements, and implications. , 2001, Journal of biomedical optics.

[4]  R R Alfano,et al.  Pulsed and cw laser fluorescence spectra from cancerous, normal, and chemically treated normal human breast and lung tissues. , 1989, Applied optics.

[5]  E. Sevick-Muraca,et al.  Quantitative optical spectroscopy for tissue diagnosis. , 1996, Annual review of physical chemistry.

[6]  Asima Pradhan,et al.  A comparative study of intrinsic versus bulk polarized fluorescence in cervical tissues , 2008, SPIE BiOS.

[7]  Prasanta K. Panigrahi,et al.  Characterizing fluorescence spectral features of cancer, benign, and normal human breast tissues through wavelet transform and singular value decomposition , 2009, European Conference on Biomedical Optics.

[8]  R. Alfano,et al.  Spectroscopic differences between human cancer and normal lung and breast tissues , 1989, Lasers in surgery and medicine.

[9]  Asima Pradhan,et al.  Wavelet transform of breast tissue fluorescence spectra: a technique for diagnosis of tumors , 2003 .

[10]  N. Ramanujam Fluorescence spectroscopy of neoplastic and non-neoplastic tissues. , 2000, Neoplasia.

[11]  Asima Pradhan,et al.  Wavelet-based characterization of spectral fluctuations in normal, benign, and cancerous human breast tissues. , 2005, Journal of biomedical optics.

[12]  Fluorescence tomographical studies on breast tissue with Cancer , 1990, Naturwissenschaften.

[13]  S. Majumder,et al.  Polarized fluorescence spectroscopy of human tissues. , 2002, Optics letters.

[14]  B. Wilson,et al.  In Vivo Fluorescence Spectroscopy and Imaging for Oncological Applications , 1998, Photochemistry and photobiology.

[15]  D. Choy,et al.  Fluorescence spectra from cancerous and normal human breast and lung tissues , 1987, Annual Meeting Optical Society of America.

[16]  N Ramanujam,et al.  In vivo diagnosis of cervical intraepithelial neoplasia using 337-nm-excited laser-induced fluorescence. , 1994, Proceedings of the National Academy of Sciences of the United States of America.