Notice of RetractionThe Sprayable Agarose/Gelatin as Wound Skin Dressing

Rapid and exact healing of skin wound, such as severe burns, trauma, diabetic, decubitus or venous stasis ulcers, is desirable in clinical. In this paper, the degraded agarose was mixed with gelatin as sprayable wound skin dressing. Agarose with different molecular weight was obtained through the degradation of agarose with hydrogen peroxide for different intervals. The formation of agarose gel was monitored by scattered light turbidimeter. The degraded agarose was activated by epichlorohydrin. The activated agarose/gelatin solution was sprayed to form gel coating rabbit wound skin. The gel dressing was not toxic and had a good repair effect on rabbit skin lesion without infection and liquid exudation. H&E staining results showed that the repair tissue was similar to the normal one. The activated low molecular agarose /gelatin gels are promising biomaterials as wound dressings for healing burns or ulcers.

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