Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine
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H. Mitsuya | K. Maeda | Y. Yasutake | N. Tamura | S. Hattori | K. Matsuda | S. Kohgo
[1] K. Anderson,et al. Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV‐1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine , 2019, Protein science : a publication of the Protein Society.
[2] Eddy Arnold,et al. Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation , 2019, Proceedings of the National Academy of Sciences.
[3] H. Mitsuya,et al. Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors. , 2019, Biochemical and biophysical research communications.
[4] S. Sarafianos,et al. CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus , 2019, Antimicrobial Agents and Chemotherapy.
[5] T. Liang,et al. Development of Direct-acting Antiviral and Host-targeting Agents for Treatment of Hepatitis B Virus Infection. , 2019, Gastroenterology.
[6] S. Sarafianos,et al. The High Genetic Barrier of EFdA/MK-8591 Stems from Strong Interactions with the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase. , 2018, Cell chemical biology.
[7] H. Mitsuya,et al. HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir , 2018, Scientific Reports.
[8] H. Chan,et al. Tenofovir Alafenamide: A Review in Chronic Hepatitis B , 2017, Drugs.
[9] A. Cuconati,et al. Hepatitis B Virus , 2017, Methods in Molecular Biology.
[10] S. Sarafianos,et al. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) , 2016, Proceedings of the National Academy of Sciences.
[11] J. Casado. Renal and Bone Toxicity with the Use of Tenofovir: Understanding at the End. , 2016, AIDS reviews.
[12] S. Tuske,et al. Structure of HIV‐1 reverse transcriptase bound to a novel 38‐mer hairpin template‐primer DNA aptamer , 2015, Protein science : a publication of the Protein Society.
[13] E. De Clercq. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF). , 2016, Biochemical pharmacology.
[14] Y. Yasutake,et al. Structure of the HIV-1 reverse transcriptase Q151M mutant: insights into the inhibitor resistance of HIV-1 reverse transcriptase and the structure of the nucleotide-binding pocket of Hepatitis B virus polymerase , 2015, Acta crystallographica. Section F, Structural biology communications.
[15] S. Sarafianos,et al. 4′‐modified nucleoside analogs: Potent inhibitors active against entecavir‐resistant hepatitis B virus , 2015, Hepatology.
[16] Y. Karino,et al. Characterization of novel entecavir resistance mutations. , 2015, Journal of hepatology.
[17] A. Zlotnick,et al. Encapsidated hepatitis B virus reverse transcriptase is poised on an ordered RNA lattice , 2014, Proceedings of the National Academy of Sciences.
[18] Alberto J. M. Martin,et al. An integrated molecular dynamics, principal component analysis and residue interaction network approach reveals the impact of M184V mutation on HIV reverse transcriptase resistance to lamivudine. , 2014, Molecular bioSystems.
[19] H. Mitsuya,et al. Delayed Emergence of HIV-1 Variants Resistant to 4′-Ethy Nyl-2-Fluoro-2′-Deoxyadenosine: Comparative Sequential Passage Study with Lamivudine, Tenofovir, Emtricitabine and BMS-986001 , 2014, Antiviral therapy.
[20] N. Ferguson,et al. Large-Scale Production and Structural and Biophysical Characterizations of the Human Hepatitis B Virus Polymerase , 2013, Journal of Virology.
[21] Randy J. Read,et al. Overview of the CCP4 suite and current developments , 2011, Acta crystallographica. Section D, Biological crystallography.
[22] N. Pannu,et al. REFMAC5 for the refinement of macromolecular crystal structures , 2011, Acta crystallographica. Section D, Biological crystallography.
[23] Jason D. Fowler,et al. Pre-Steady-State Kinetic Analysis of the Incorporation of Anti-HIV Nucleotide Analogs Catalyzed by Human X- and Y-Family DNA Polymerases , 2010, Antimicrobial Agents and Chemotherapy.
[24] Roger A. Jones,et al. Structural basis of HIV-1 resistance to AZT by excision , 2010, Nature Structural &Molecular Biology.
[25] P. Emsley,et al. Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.
[26] W. Kabsch. XDS , 2010, Acta crystallographica. Section D, Biological crystallography.
[27] Randy J. Read,et al. Acta Crystallographica Section D Biological , 2003 .
[28] Vincent B. Chen,et al. Correspondence e-mail: , 2000 .
[29] Roger A. Jones,et al. Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance* , 2009, The Journal of Biological Chemistry.
[30] M. Nassal. New insights into HBV replication: new opportunities for improved therapies , 2009 .
[31] Lin Shen,et al. The HBV drug entecavir - effects on HIV-1 replication and resistance. , 2007, The New England journal of medicine.
[32] Christopher M. Bailey,et al. Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine , 2007, Antimicrobial Agents and Chemotherapy.
[33] Ronald E. Rose,et al. Inhibition of Hepatitis B Virus Polymerase by Entecavir , 2007, Journal of Virology.
[34] Colin W Shepard,et al. Hepatitis B virus infection: epidemiology and vaccination. , 2006, Epidemiologic reviews.
[35] L. Bacheler,et al. The K65R Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Exhibits Bidirectional Phenotypic Antagonism with Thymidine Analog Mutations , 2006, Journal of Virology.
[36] Jeffrey J. DeStefano,et al. Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity , 2006, Nucleic acids research.
[37] P. Evans,et al. Scaling and assessment of data quality. , 2006, Acta crystallographica. Section D, Biological crystallography.
[38] M. Poirier,et al. Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells. , 2005, Mutagenesis.
[39] Roger A. Jones,et al. Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir , 2004, Nature Structural &Molecular Biology.
[40] D. Lavanchy,et al. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures , 2004, Journal of viral hepatitis.
[41] M. Otto,et al. Mechanism of Antiviral Activities of 3′-Substituted L-Nucleosides against 3Tc-Resistant HBV Polymerase: A Molecular Modelling Approach , 2003, Antiviral chemistry & chemotherapy.
[42] A. D. Clark,et al. Structures of HIV‐1 reverse transcriptase with pre‐ and post‐translocation AZTMP‐terminated DNA , 2002, The EMBO journal.
[43] R. J. Colonno,et al. Efficacies of Entecavir against Lamivudine-Resistant Hepatitis B Virus Replication and Recombinant Polymerases In Vitro , 2002, Antimicrobial Agents and Chemotherapy.
[44] S. Sarafianos,et al. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase. , 2000, Journal of molecular biology.
[45] C. Seeger,et al. Hepatitis B Virus Biology , 2000, Microbiology and Molecular Biology Reviews.
[46] A. D. Clark,et al. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[47] K. Anderson,et al. Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase. , 1999, Biochemistry.
[48] M. Wainberg,et al. Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1 , 1996, Journal of virology.
[49] M. Wainberg,et al. Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[50] E. Arnold,et al. Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[51] R. Bartenschlager,et al. Hepadnavirus P protein utilizes a tyrosine residue in the TP domain to prime reverse transcription , 1994, Journal of virology.
[52] D. Katzenstein,et al. Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations. , 1994, The Journal of infectious diseases.
[53] F. Zoulim,et al. Reverse transcription in hepatitis B viruses is primed by a tyrosine residue of the polymerase , 1994, Journal of virology.
[54] D. Galas,et al. A simple method for site-directed mutagenesis using the polymerase chain reaction. , 1989, Nucleic acids research.
[55] J. Summers,et al. Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate , 1982, Cell.