A case of multiple pyogenic granulomas of the trunk successfully treated with topical β‐blockers

early PG with a greater vascular component. 7 Some authors suggest that small PGs ( < 4 mm) may also respond favorably to the topical therapy. 6 However, according to Patra et al., 7 the percentage reduc - tion in size showed no correlation with baseline size of the lesion and duration of the lesion. Moreover, we obtained a good result in our case despite the large size of the lesion. The age of the patient and the site of the lesion also did not predict the percentage reduc - tion in size. TB have proven to be safe and well- tolerated and recur - rence has not been reported. This alternative was mostly offered in cases where invasive modalities are not preferred especially in young children, incapacitated elderly, and over delicate areas like the face, nails, and gums. 5 It was also a cost- effective treatment option for patients with recurrent PG and those who are hesitant to undergo removal procedures. 5 However, all cases reported in the literature were classical solitary PGs of small size, not exceed - ing 2 cm. We herein report the first case of MGPG of a very large size (15 cm long axis) treated with TB, showing a complete response within 2 months. Our case proves the effectiveness of TB even in large PG and MGPG. In conclusion, TB represents a potential promising non- surgical option that could change the typical approach of PG, whether single or multiple, small, or large. Further randomized studies are required to determine the best regimen regarding dose, duration of applica - tion, site, and size- specific efficacy.