Deletion of the nuclear receptor RORα in macrophages does not modify the development of obesity, insulin resistance and NASH
暂无分享,去创建一个
S. Fleury | D. Dombrowicz | Benan Pelin Sermikli | B. Staels | A. Tailleux | Laurent L’homme | Sandrine Quemener | C. Duhem | B. Gross | O. Molendi-Coste | E. Vallez | L. Pineau | M. Joseph | Mathilde Le Maître | Emmanuelle Vallez
[1] M. Allison,et al. Adipose tissue-liver cross talk in the control of whole-body metabolism: implications in non-alcoholic fatty liver disease. , 2020, Gastroenterology.
[2] P. Libby,et al. Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. , 2019, Immunity.
[3] M. Heikenwalder,et al. From NASH to HCC: current concepts and future challenges , 2019, Nature Reviews Gastroenterology & Hepatology.
[4] D. Philpott,et al. Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models. , 2019, Cell reports.
[5] D. Schuppan,et al. Mouse Models of Nonalcoholic Steatohepatitis: Toward Optimization of Their Relevance to Human Nonalcoholic Steatohepatitis , 2019, Hepatology.
[6] F. Bäckhed,et al. Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding , 2019, Molecular metabolism.
[7] Aleksandra A. Kolodziejczyk,et al. The role of the microbiome in NAFLD and NASH , 2018, EMBO molecular medicine.
[8] Y. Saeys,et al. The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages , 2018, Immunity.
[9] C. Shin,et al. Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction , 2017, Scientific Reports.
[10] H. Ibrahim,et al. Novel peptide motifs from lysozyme suppress pro‐inflammatory cytokines in macrophages by antagonizing toll‐like receptor and LPS‐scavenging action , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[11] D. Hwang,et al. RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network , 2017, Nature Communications.
[12] Z. Su,et al. Retinoic acid receptor-related orphan receptor α stimulates adipose tissue inflammation by modulating endoplasmic reticulum stress , 2017, The Journal of Biological Chemistry.
[13] S. Koo,et al. RORα Induces KLF4-Mediated M2 Polarization in the Liver Macrophages that Protect against Nonalcoholic Steatohepatitis. , 2017, Cell reports.
[14] M. Lazar,et al. The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ , 2017, Genes & development.
[15] Y. Koyama,et al. Liver inflammation and fibrosis. , 2017, The Journal of clinical investigation.
[16] Fan Li,et al. Retinoid acid receptor-related orphan receptor alpha (RORα) regulates macrophage M2 polarization via activation of AMPKα. , 2016, Molecular immunology.
[17] P. Soares,et al. The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype , 2016, Genes.
[18] Z. Su,et al. Genetic Variants of Retinoic Acid Receptor-Related Orphan Receptor Alpha Determine Susceptibility to Type 2 Diabetes Mellitus in Han Chinese , 2016, Genes.
[19] V. Dixit,et al. Adipose tissue as an immunological organ , 2015, Obesity.
[20] N. Paquot,et al. Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease , 2015, Expert opinion on investigational drugs.
[21] Qinghua Sun,et al. Macrophage recruitment in obese adipose tissue , 2015, Obesity reviews : an official journal of the International Association for the Study of Obesity.
[22] Eun‐Jin Kim,et al. RORα decreases oxidative stress through the induction of SOD2 and GPx1 expression and thereby protects against nonalcoholic steatohepatitis in mice. , 2014, Antioxidants & redox signaling.
[23] Alan D. Lopez,et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 , 2014, The Lancet.
[24] J. Olefsky,et al. Macrophages, immunity, and metabolic disease. , 2014, Immunity.
[25] C. Abram,et al. Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice. , 2014, Journal of immunological methods.
[26] R. Medzhitov,et al. Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages , 2014, Cell.
[27] R. Fässler,et al. Cre recombinase induces DNA damage and tetraploidy in the absence of LoxP sites , 2014, Cell cycle.
[28] G. Rossi. Diagnosis and Classification of Diabetes Mellitus , 2011, Diabetes Care.
[29] Nathaniel S Wang,et al. Differential Transcriptional Programming of Class-Specific B Cell Memory by T-bet and RORα , 2012, Nature Immunology.
[30] A. McKenzie,et al. Rorα is essential for nuocyte development , 2011, Nature immunology.
[31] Christian Gieger,et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma , 2011, Nature Genetics.
[32] Yaohui Nie,et al. Clodronate Liposomes Improve Metabolic Profile and Reduce Visceral Adipose Macrophage Content in Diet-Induced Obese Mice , 2011, PloS one.
[33] B. Gao,et al. Inflammation‐associated interleukin‐6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin‐10–deficient mice , 2011, Hepatology.
[34] C. Bortner,et al. Transcriptional profiling reveals a role for RORalpha in regulating gene expression in obesity-associated inflammation and hepatic steatosis. , 2011, Physiological genomics.
[35] P. O S I T I O N S T A T E M E N T,et al. Diagnosis and Classification of Diabetes Mellitus , 2011, Diabetes Care.
[36] J. Dubé,et al. Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance , 2009, Diabetes.
[37] J. Olefsky,et al. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. , 2008, Cell Metabolism.
[38] R. Gellibolian,et al. Lysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis media , 2008, BMC Infectious Diseases.
[39] D. Koller,et al. The Immunological Genome Project: networks of gene expression in immune cells , 2008, Nature Immunology.
[40] G. Muscat,et al. The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism , 2008, Journal of Biological Chemistry.
[41] Chen Dong,et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. , 2008, Immunity.
[42] J. Gimble,et al. Gene expression profiling reveals a regulatory role for RORα and RORγ in phase I and phase II metabolism , 2007 .
[43] J. Gimble,et al. Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism. , 2007, Physiological genomics.
[44] G. Striker,et al. Amelioration of oxidant stress by the defensin lysozyme. , 2006, American journal of physiology. Endocrinology and metabolism.
[45] A. Jetten,et al. Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development. , 2006, Advances in developmental biology.
[46] Nicolas Cermakian,et al. Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors , 2005, Journal of biological rhythms.
[47] J. Ludvigsson,et al. RAR-related orphan receptor A isoform 1 (RORa1) is disrupted by a balanced translocation t(4;15)(q22.3;q21.3) associated with severe obesity , 2005, European Journal of Human Genetics.
[48] T. Korfhagen,et al. Mouse lysozyme M is important in pulmonary host defense against Klebsiella pneumoniae infection. , 2004, American journal of respiratory and critical care medicine.
[49] T. Graf,et al. Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan. , 2003, Blood.
[50] B. Thyagarajan,et al. Mammalian genomes contain active recombinase recognition sites. , 2000, Gene.
[51] M. Ogundele. A novel anti-inflammatory activity of lysozyme: modulation of serum complement activation. , 1998, Mediators of inflammation.
[52] T. Kurasawa,et al. Effects of murine lysozyme on lipopolysaccharide-induced biological activities. , 1996, FEMS immunology and medical microbiology.
[53] J. McGee,et al. Kupffer cell number is normal, but their lysozyme content is reduced in alcoholic liver disease. , 1989, Journal of hepatology.
[54] P. Cloke,et al. Lysozyme in chronic liver disease: a biochemical and histological study. , 1982, Journal of clinical pathology.
[55] J. Lindemans,et al. Plasma lysozyme level and reticuloendothelial system function in human liver disease. , 1981, Clinica chimica acta; international journal of clinical chemistry.