Prevention of postmenopausal osteoporosis by hormone treatment of the menopause.

ALTHOUGH osteoporosis occurs in both sexes, it is particularly prevalent and severe in postmenopausal women. Our previous finding, that postmenopausal loss of compact bone in the radius was caused by a decrease in ovarian function rather than by ageing as such, sug¬ gested that replacement therapy with ovarian hormones should prevent postmenopausal osteo¬ porosis.1 The purpose of the present study was to explore this possibility by comparing the cor¬ tical thickness measurements of the radius in two groups of women who had undergone oophorectomy. One group had received replacement therapy and the other had not. It will be shown that, in most cases, hormone treatment of the menopause does prevent or delay the onset of cortical bone atrophy of the radius.

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