Author's Personal Copy Computerized Medical Imaging and Graphics Semi-automated Assessment of Left Ventricular Mass Using Transaxial Tc-99m Sestamibi Spect Imaging

The "left ventricular mass" (LVM) using Tc-99m Sestamibi SPECT imaging may be a useful parameter to quantitatively assess the left ventricle and hence its function. The LVM was determined without reorienting the images along the long axis of the left ventricle. A comparison with reoriented SPECT images was then performed. The LVM showed the expected variations among different pathological heart conditions and the control subjects. The left ventricular mass obtained from non-reoriented tomographic views of the myocardium can be a useful index to quantitatively assess various heart conditions where the myocardium lacks perfusion either between rest and stress studies or similar conditions in longitudinal studies.

[1]  Julius T. Tou,et al.  Pattern Recognition Principles , 1974 .

[2]  Bertil Gustafsson,et al.  On the direct Fourier method for computer tomography , 2000, IEEE Transactions on Medical Imaging.

[3]  T. Mexia,et al.  Author ' s personal copy , 2009 .

[4]  L. P. Yaroslavsky,et al.  DFT and DCT based discrete sinc-interpolation methods for direct Fourier tomographic reconstruction , 2003, 3rd International Symposium on Image and Signal Processing and Analysis, 2003. ISPA 2003. Proceedings of the.

[5]  Guido Germano,et al.  Automatic quantification of myocardial perfusion stress-rest change: a new measure of ischemia. , 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  Y. Yonekura,et al.  Stress thallium-201 transaxial emission computed tomography: quantitative versus qualitative analysis for evaluation of coronary artery disease. , 1984, Journal of the American College of Cardiology.

[7]  S. Larsson,et al.  Gamma camera emission tomography. Development and properties of a multi-sectional emission computed tomography system. , 1980, Acta radiologica. Supplementum.

[8]  Á. De Moraes,et al.  Echocardiographic assessment of the different left ventricular geometric patterns in hypertensive patients. , 2001, Arquivos brasileiros de cardiologia.

[9]  B. Nowak,et al.  Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: MRI validation and comparison of the Emory Cardiac Tool Box with QGS and 4D-MSPECT. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[10]  Centering Artifacts Manifesting As Anterior Wall Defects On Myocardial SPECT Imaging , 2002 .

[11]  J. Corbett,et al.  Determination of left ventricular mass by single-photon emission computed tomography with thallium-201. , 1984, The American journal of cardiology.

[12]  丸山 薫.  Left ventricular mass index measured by quantitative gated myocardial SPECT with 99mTc-tetrofosmin : A comparison with echocardiography , 2003 .

[13]  Yoshiharu Yonekura,et al.  Segmental analysis of stress thallium myocardial emission tomography for localization of coronary artery disease , 2004, European Journal of Nuclear Medicine.

[14]  Johan Waldén,et al.  Analysis of the direct Fourier method for computer tomography , 2000, IEEE Transactions on Medical Imaging.

[15]  D. Berman,et al.  Quantitative same-day rest-stress technetium-99m-sestamibi SPECT: definition and validation of stress normal limits and criteria for abnormality. , 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[16]  Abdul Ghapor Hussin,et al.  Computerized Medical Imaging and Graphics. , 2011 .

[17]  R. Pettigrew,et al.  Three-dimensional displays of left ventricular epicardial surface from standard cardiac SPECT perfusion quantification techniques. , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[18]  H. S. Klopfenstein,et al.  Left ventricular mass in the elderly. The Cardiovascular Health Study. , 1997, Hypertension.

[19]  E. Depuey,et al.  Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease. , 1988, Circulation.

[20]  Murilo Foppa,et al.  Echocardiography-based left ventricular mass estimation. How should we define hypertrophy? , 2005, Cardiovascular ultrasound.

[21]  Avinash C. Kak,et al.  3. Algorithms for Reconstruction with Nondiffracting Sources , 2001 .

[22]  L. Becker,et al.  Improved diagnostic performance of exercise thallium-201 single photon emission computed tomography over planar imaging in the diagnosis of coronary artery disease: a receiver operating characteristic analysis. , 1989, Journal of the American College of Cardiology.

[23]  Avinash C. Kak,et al.  Principles of computerized tomographic imaging , 2001, Classics in applied mathematics.

[24]  A. Okizaki,et al.  Estimation with Tc-99m tetrofosmin SPECT of salvaged myocardial mass after emergent reperfusion therapy in acute myocardial infarction , 2003, Annals of nuclear medicine.

[25]  D S Berman,et al.  Quantification of rotational thallium-201 myocardial tomography. , 1985, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[26]  V. Dilsizian,et al.  Thallium-201 and technetium-99m-sestamibi for assessing viable myocardium. , 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[27]  D. Berman,et al.  Clinical validation of automatic quantitative defect size in rest technetium-99m-sestamibi myocardial perfusion SPECT. , 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.