A T Cell Inflammatory Phenotype is Associated with Autoimmune Toxicity of the PI3K Inhibitor Duvelisib in Chronic Lymphocytic Leukemia
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Emily M. Thrash | S. Tyekucheva | S. Fernandes | P. Armand | M. Davids | D. Fisher | Jennifer R. Brown | Deepti Gadi | J. Lederer | Alexander Vartanov | J. Arnason | Oreofe O. Odejide | John-Hanson Machado | Alec Griffith | Zixu Wang | Brandon Lee | Timothy Lehmberg | Stephen P. Martindale | Vanessa Rai | A. Griffith
[1] S. Tyekucheva,et al. A phase 1b/2 study of duvelisib in combination with FCR (DFCR) for frontline therapy for younger CLL patients , 2020, Leukemia.
[2] Thomas G. Dietterich. What is machine learning? , 2015, Archives of Disease in Childhood.
[3] Stephen Li,et al. Automated Data Cleanup for Mass Cytometry , 2019, Cytometry. Part A : the journal of the International Society for Analytical Cytology.
[4] S. Tyekucheva,et al. Imbalance in T Cell Subsets Triggers the Autoimmune Toxicity of PI3K Inhibitors in CLL , 2019, Blood.
[5] A. Zelenetz,et al. Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[6] I. Flinn,et al. DYNAMO: A Phase II Study of Duvelisib (IPI-145) in Patients With Refractory Indolent Non-Hodgkin Lymphoma. , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[7] F. Bosch,et al. The phase 3 DUO trial: duvelisib vs ofatumumab in relapsed and refractory CLL/SLL. , 2018, Blood.
[8] J. Ritz,et al. Mass Cytometry Identifies T Cell Populations Associated with Severe Hepatotoxicity in CLL Patients on Upfront Idelalisib , 2018, Blood.
[9] Mark D. Robinson,et al. Compensation of Signal Spillover in Suspension and Imaging Mass Cytometry , 2018, Cell systems.
[10] A. Zelenetz,et al. Risk factors for grade 3/4 transaminase elevation in patients with chronic lymphocytic leukemia treated with idelalisib , 2017, Leukemia.
[11] J. Lieberman,et al. Human regulatory T cells undergo self-inflicted damage via granzyme pathways upon activation. , 2017, JCI insight.
[12] Philippe Foubert,et al. PI3Kγ is a molecular switch that controls immune suppression , 2016, Nature.
[13] Hao Chen,et al. Cytofkit: A Bioconductor Package for an Integrated Mass Cytometry Data Analysis Pipeline , 2016, PLoS Comput. Biol..
[14] L. Rassenti,et al. Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity. , 2016, Blood.
[15] Eli R. Zunder,et al. Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm , 2015, Nature Protocols.
[16] Bonnie Tillotson,et al. PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models. , 2013, Chemistry & biology.
[17] Sean C. Bendall,et al. Normalization of mass cytometry data with bead standards , 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.
[18] Xiangpei Li,et al. CD4+CD25+CD127low/− T Cells: A More Specific Treg Population in Human Peripheral Blood , 2012, Inflammation.
[19] J. Flint,et al. Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties , 2010, Proceedings of the National Academy of Sciences.
[20] Davis J. McCarthy,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[21] D. Littman,et al. The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells , 2006, Cell.
[22] Laurens van der Maaten,et al. Accelerating t-SNE using tree-based algorithms , 2014, J. Mach. Learn. Res..
[23] D. Littman,et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. , 2006, Cell.