The activating enzyme of NEDD8 inhibits steroid receptor function.
暂无分享,去创建一个
K. Nephew | R. Bigsby | X. Long | M. Fan | J. Bailey | Chad A Reed | E. A. Gize | E. Osborne | Eric A Kirk
[1] C. Osborne,et al. Forkhead Homologue in Rhabdomyosarcoma Functions as a Bifunctional Nuclear Receptor-interacting Protein with Both Coactivator and Corepressor Functions* , 2001, The Journal of Biological Chemistry.
[2] C. Powers,et al. Ribozyme Targeting Demonstrates That the Nuclear Receptor Coactivator AIB1 Is a Rate-limiting Factor for Estrogen-dependent Growth of Human MCF-7 Breast Cancer Cells* , 2001, The Journal of Biological Chemistry.
[3] A. Shevchenko,et al. Promotion of NEDD8-CUL1 Conjugate Cleavage by COP9 Signalosome , 2001, Science.
[4] C. Schwechheimer,et al. Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response , 2001, Science.
[5] H. Ruffner,et al. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[6] M. Erdos,et al. Role of direct interaction in BRCA1 inhibition of estrogen receptor activity , 2001, Oncogene.
[7] J. Palvimo,et al. Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[8] Jason D. Hoeksema,et al. Analysis of Estrogen Receptor Interaction with a Repressor of Estrogen Receptor Activity (REA) and the Regulation of Estrogen Receptor Transcriptional Activity by REA* , 2000, The Journal of Biological Chemistry.
[9] P. Chambon,et al. Dimerization with Retinoid X Receptors and Phosphorylation Modulate the Retinoic Acid-induced Degradation of Retinoic Acid Receptors α and γ through the Ubiquitin-Proteasome Pathway* , 2000, The Journal of Biological Chemistry.
[10] Angus Chen,et al. Conjugation of Nedd8 to CUL1 Enhances the Ability of the ROC1-CUL1 Complex to Promote Ubiquitin Polymerization* , 2000, The Journal of Biological Chemistry.
[11] B. Katzenellenbogen,et al. Prothymosin Alpha Selectively Enhances Estrogen Receptor Transcriptional Activity by Interacting with a Repressor of Estrogen Receptor Activity , 2000, Molecular and Cellular Biology.
[12] B. O’Malley,et al. The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation , 2000 .
[13] C. Klinge,et al. Estrogen receptor interaction with co-activators and co-repressors☆ , 2000, Steroids.
[14] E. Lightcap,et al. A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[15] V. Chau,et al. Nedd8 Modification of Cul-1 Activates SCFβTrCP-Dependent Ubiquitination of IκBα , 2000, Molecular and Cellular Biology.
[16] R. Neve,et al. The Amyloid Precursor Protein-binding Protein APP-BP1 Drives the Cell Cycle through the S-M Checkpoint and Causes Apoptosis in Neurons* , 2000, The Journal of Biological Chemistry.
[17] C. Osborne,et al. Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of ER-mediated transactivation. , 2000, Molecular endocrinology.
[18] J. Kurebayashi,et al. Expression Levels of Estrogen Receptor-α, Estrogen Receptor-β, Coactivators, and Corepressors in Breast Cancer , 2000 .
[19] C. Lange,et al. Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[20] K. Nephew,et al. Effects of oral administration of tamoxifen, toremifene, dehydroepiandrosterone, and vorozole on uterine histomorphology in the rat. , 2000, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[21] K. Nephew,et al. Effect of Estradiol on Estrogen Receptor Expression in Rat Uterine Cell Types1 , 2000, Biology of reproduction.
[22] Sandip K. Mishra,et al. Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor , 2000, Nature Cell Biology.
[23] B. O’Malley,et al. FRAP reveals that mobility of oestrogen receptor-α is ligand- and proteasome-dependent , 2000, Nature Cell Biology.
[24] M. Gilman,et al. Proteasome‐mediated degradation of transcriptional activators correlates with activation domain potency in vivo , 1999, The EMBO journal.
[25] B. Clurman,et al. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. , 1999, Genes & development.
[26] R Stearman,et al. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[27] B. Katzenellenbogen,et al. An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[28] M. Erdos,et al. BRCA1 inhibition of estrogen receptor signaling in transfected cells. , 1999, Science.
[29] E. Yeh,et al. Identification of the Activating and Conjugating Enzymes of the NEDD8 Conjugation Pathway* , 1999, The Journal of Biological Chemistry.
[30] Z. Ronai,et al. Recruitment of a ROC1–CUL1 Ubiquitin Ligase by Skp1 and HOS to Catalyze the Ubiquitination of IκBα , 1999 .
[31] B. O’Malley,et al. Proteasome-dependent degradation of the human estrogen receptor. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[32] M. Tsai,et al. The Angelman Syndrome-Associated Protein, E6-AP, Is a Coactivator for the Nuclear Hormone Receptor Superfamily , 1999, Molecular and Cellular Biology.
[33] Z. Ronai,et al. Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. , 1999, Molecular cell.
[34] R J Fletterick,et al. Structure and specificity of nuclear receptor-coactivator interactions. , 1998, Genes & development.
[35] K. Nephew,et al. Studies of dehydroepiandrosterone (DHEA) with the human estrogen receptor in yeast , 1998, Molecular and Cellular Endocrinology.
[36] R. Deshaies,et al. Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[37] M. Estelle,et al. The ubiquitin-related protein RUB1 and auxin response in Arabidopsis. , 1998, Science.
[38] R J Fletterick,et al. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. , 1998, Science.
[39] H. Nakshatri,et al. NF-κB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1α , 1998 .
[40] S. Jentsch,et al. A novel protein modification pathway related to the ubiquitin system , 1998, The EMBO journal.
[41] M. Goebl,et al. Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. , 1998, Genes & development.
[42] B. O’Malley,et al. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. , 1998, Science.
[43] P. Meltzer,et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. , 1997, Science.
[44] David M. Heery,et al. A signature motif in transcriptional co-activators mediates binding to nuclear receptors , 1997, Nature.
[45] K. Horwitz,et al. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. , 1997, Molecular endocrinology.
[46] A. Maggi,et al. Oligonucleotide squelching reveals the mechanism of estrogen receptor autologous down-regulation. , 1997, Molecular endocrinology.
[47] P. Chambon,et al. SUG1, a Putative Transcriptional Mediator and Subunit of the PA700 Proteasome Regulatory Complex, Is a DNA Helicase* , 1997, The Journal of Biological Chemistry.
[48] C. Meier. Regulation of gene expression by nuclear hormone receptors. , 1997, Journal of receptor and signal transduction research.
[49] G. Jenster,et al. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. , 1997, Recent progress in hormone research.
[50] B. Katzenellenbogen,et al. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[51] J. Gustafsson,et al. Cloning of a novel receptor expressed in rat prostate and ovary. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[52] J. Pink,et al. Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines. , 1996, Cancer research.
[53] P. Chambon,et al. Differential ligand‐dependent interactions between the AF‐2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. , 1996, The EMBO journal.
[54] K. Nephew,et al. Tamoxifen-induced proto-oncogene expression persists in uterine endometrial epithelium. , 1996, Endocrinology.
[55] K. Umesono,et al. The nuclear receptor superfamily: The second decade , 1995, Cell.
[56] K. Nephew,et al. Cellular localization of estradiol-induced c-fos messenger ribonucleic acid in the rat uterus: c-fos expression and uterine cell proliferation do not correlate strictly. , 1995, Endocrinology.
[57] M. Parker,et al. Interaction of proteins with transcriptionally active estrogen receptors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[58] Yang Li,et al. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II , 1994, Cell.
[59] K. Nephew,et al. Estrogen differentially affects c-jun expression in uterine tissue compartments. , 1994, Endocrinology.
[60] R. Bigsby,et al. Differentially regulated immediate early genes in the rat uterus. , 1994, Endocrinology.
[61] G. Leclercq,et al. Estradiol-induced Down-regulation of estrogen receptor. Effect of various modulators of protein synthesis and expression , 1994, The Journal of Steroid Biochemistry and Molecular Biology.
[62] B. O’Malley,et al. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. , 1994, Annual review of biochemistry.
[63] V. Mahesh,et al. Regulation of estrogen receptor protein and messenger ribonucleic acid by estradiol and progesterone in rat uterus , 1993, The Journal of Steroid Biochemistry and Molecular Biology.
[64] J. Gorski,et al. Involvement of the coding sequence for the estrogen receptor gene in autologous ligand-dependent down-regulation. , 1993, Molecular endocrinology.
[65] R. Treisman,et al. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain , 1993, Cell.
[66] V. Mahesh,et al. Changes in rat uterine estrogen receptor messenger ribonucleic acid levels during estrogen- and progesterone-induced estrogen receptor depletion and subsequent replenishment. , 1993, Biology of reproduction.
[67] J. Baxter,et al. The limits of the cellular capacity to mediate an estrogen response. , 1992, Molecular endocrinology.
[68] J. Laborda,et al. 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO. , 1991, Nucleic acids research.
[69] pierre-Marie Martin,et al. Expression of estrogen receptor and its messenger ribonucleic acid in the MCF-7 cell line: multiparametric analysis of its processing and regulation by estrogen , 1990, Molecular and Cellular Endocrinology.
[70] J. Russo,et al. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. , 1990, Cancer research.
[71] M. Lippman,et al. Role of an estrogen receptor-dependent mechanism in the regulation of estrogen receptor mRNA in MCF-7 cells. , 1989, Molecular endocrinology.
[72] F. Levy,et al. Autologous down-regulation of messenger ribonucleic acid and protein levels for estrogen receptors in MCF-7 cells: an inverse correlation to progesterone receptor levels. , 1989, Endocrinology.
[73] P Chambon,et al. The 5′ flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c‐Ha‐ras oncoprotein and the c‐jun protein. , 1989, The EMBO journal.
[74] B. Katzenellenbogen,et al. Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and growth factors. , 1989, Molecular endocrinology.
[75] P. Chambon,et al. Regulation of the estrogen receptor in MCF-7 cells by estradiol. , 1988, Molecular endocrinology.
[76] J. Copland,et al. Discrete early changes in cellular subpopulations of rat uterine and anterior pituitary estrogen receptors in response to acute exposure to exogenous estradiol. , 1987, Journal of steroid biochemistry.
[77] W. McGuire,et al. Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing. , 1978, The Journal of biological chemistry.
[78] J. Cidlowski,et al. The dynamics of intracellular estrogen receptor regulation as influenced by 17beta-estradiol. , 1978, Biology of reproduction.
[79] J. Cidlowski,et al. Estrogenic regulation of cytoplasmic receptor populations in estrogen-responsive tissues of the rat. , 1974, Endocrinology.
[80] J. Gustafsson,et al. Cloning of a novel estrogen receptor expressed in rat prostate and ovary , 2022 .