The diagnostic accuracy of dual-view digital mammography, single-view breast tomosynthesis and a dual-view combination of breast tomosynthesis and digital mammography in a free-response observer performance study.

The purpose of the present study was to compare the diagnostic accuracy of dual-view digital mammography (DM), single-view breast tomosynthesis (BT) and BT combined with the opposite DM view. Patients with subtle lesions were selected to undergo BT examinations. Two radiologists who are non-participants in the study and have experience in using DM and BT determined the locations and extents of lesions in the images. Five expert mammographers interpreted the cases using the free-response paradigm. The task was to mark and rate clinically reportable findings suspicious for malignancy and clinically relevant benign findings. The marks were scored with reference to the outlined regions into lesion localization or non-lesion localization, and analysed by the jackknife alternative free-response receiver operating characteristic method. The analysis yielded statistically significant differences between the combined modality and dual-view DM (p < 0.05). No differences were found between single-view BT and dual-view DM or between single-view BT and the combined modality.

[1]  Anders Tingberg,et al.  Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings , 2008, European Radiology.

[2]  Tor D Tosteson,et al.  Digital breast tomosynthesis: initial experience in 98 women with abnormal digital screening mammography. , 2007, AJR. American journal of roentgenology.

[3]  F R Verdun,et al.  Estimation of the noisy component of anatomical backgrounds. , 1999, Medical physics.

[4]  Joseph Y. Lo,et al.  Digital breast tomosynthesis using an amorphous selenium flat panel detector , 2005, SPIE Medical Imaging.

[5]  C. D'Orsi,et al.  Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening , 2006 .

[6]  Magnus Båth,et al.  ViewDEX 2.0: a Java-based DICOM-compatible software for observer performance studies , 2009, Medical Imaging.

[7]  C E Metz,et al.  Some practical issues of experimental design and data analysis in radiological ROC studies. , 1989, Investigative radiology.

[8]  M. Ruschin,et al.  A software tool for increased efficiency in observer performance studies in radiology. , 2005, Radiation protection dosimetry.

[9]  Per Skaane,et al.  Screen-film mammography versus full-field digital mammography with soft-copy reading: randomized trial in a population-based screening program--the Oslo II Study. , 2004, Radiology.

[10]  D Laming,et al.  Improving the detection of cancer in the screening of mammograms , 2000, Journal of medical screening.

[11]  P. Langenberg,et al.  Breast Imaging Reporting and Data System: inter- and intraobserver variability in feature analysis and final assessment. , 2000, AJR. American journal of roentgenology.

[12]  David Gur,et al.  Digital breast tomosynthesis: observer performance study. , 2009, AJR. American journal of roentgenology.

[13]  Dev P Chakraborty,et al.  Recent advances in observer performance methodology: jackknife free-response ROC (JAFROC). , 2005, Radiation protection dosimetry.

[14]  Thomas Mertelmeier,et al.  Optimizing filtered backprojection reconstruction for a breast tomosynthesis prototype device , 2006, SPIE Medical Imaging.

[15]  Anders Tingberg,et al.  Breast tomosynthesis: Accuracy of tumor measurement compared with digital mammography and ultrasonography , 2010, Acta radiologica.

[16]  C. D'Orsi,et al.  Diagnostic Performance of Digital Versus Film Mammography for Breast-Cancer Screening , 2005, The New England journal of medicine.

[17]  Dev P Chakraborty,et al.  Observer studies involving detection and localization: modeling, analysis, and validation. , 2004, Medical physics.

[18]  L. Liberman,et al.  Breast imaging reporting and data system (BI-RADS). , 2002, Radiologic clinics of North America.

[19]  Sian Taylor-Phillips,et al.  The effect of digitising film prior mammograms on radiologists' performance in breast screening: a JAFROC study , 2009, Medical Imaging.

[20]  J M Lewin,et al.  Comparison of full-field digital mammography with screen-film mammography for cancer detection: results of 4,945 paired examinations. , 2001, Radiology.