Superficial Siderosis in Central Nervous System: A Case Report and Literature Review

Superficial siderosis (SS) in central nervous system is a rare, slowly progressive disease and usually misdiagnosed or diag- nosed too late when the patient is chronically devastated. A 55-year-old man with deafness and gait disturbance for ten years was referred from otorhinologist for evaluation of brain. Magnetic resonance image (MRI) showed symmetric hypointense rim partially delineated the bilateral hemisphere on gradient-recalled-echo T2-weighted image, and it was diagnosed as he- mosiderin deposition in subarachnoid and subpial meningeal layer. The correct diagnosis of cerebral superficial siderosis can be achieved by careful neurological examination and MRI because computed tomography findings and symptoms are am - biguous. Serial follow-up of imaging study and education for patient are necessary to prevent progression of SS. (Korean J Neurotrauma 2013;9:139-141)

[1]  S. Frisch,et al.  Superficial siderosis of the central nervous system – treatment with steroids? , 2009, Journal of clinical pharmacy and therapeutics.

[2]  M. Cevette,et al.  Cochlear implant patients with superficial siderosis. , 2009, Journal of the American Academy of Audiology.

[3]  H. Zetterberg,et al.  Hyperphosphorylation of tau protein in superficial CNS siderosis , 2008, Journal of the Neurological Sciences.

[4]  A. Koeppen,et al.  The pathology of superficial siderosis of the central nervous system , 2008, Acta Neuropathologica.

[5]  Neeraj Kumar Superficial siderosis: associations and therapeutic implications. , 2007, Archives of neurology.

[6]  R. Llinas,et al.  Superficial siderosis: a case report and review of the literature , 2007, Nature Clinical Practice Neurology.

[7]  B. Branstetter,et al.  Successful cochlear implantation in a patient with superficial siderosis. , 2006, American journal of otolaryngology.

[8]  D. Piepgras,et al.  Superficial siderosis , 2006, Neurology.

[9]  J. Stevens,et al.  REVIEW ARTICLESuperficial siderosis of the central nervous system , 1995 .

[10]  J. Faiss,et al.  Superficial siderosis of the central nervous system. , 1994, Archives of gerontology and geriatrics.

[11]  Koeppen Ah Superficial siderosis of the central nervous system. , 1971 .