Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells.

[1]  X. Castells,et al.  Modelling mutational landscapes of human cancers in vitro , 2014, Scientific Reports.

[2]  Michael P. Schroeder,et al.  IntOGen-mutations identifies cancer drivers across tumor types , 2013, Nature Methods.

[3]  David T. W. Jones,et al.  Signatures of mutational processes in human cancer , 2013, Nature.

[4]  K. Kinzler,et al.  Cancer Genome Landscapes , 2013, Science.

[5]  Niruthika Sritharan,et al.  Genomic landscape of non-small-cell lung cancer in smokers and never-smokers , 2013, Thorax.

[6]  M. Stampfer,et al.  An Integrated Human Mammary Epithelial Cell Culture System for Studying Carcinogenesis and Aging , 2013 .

[7]  A. Borowsky,et al.  Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia. , 2012, Cancer research.

[8]  M. Stampfer,et al.  Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells , 2011, Aging cell.

[9]  Martha R. Stampfer,et al.  Epigenetic regulation of normal human mammary cell type-specific miRNAs. , 2011, Genome research.

[10]  A. McKenna,et al.  The Mutational Landscape of Head and Neck Squamous Cell Carcinoma , 2011, Science.

[11]  M. Jackson,et al.  TGF-β signaling engages an ATM-CHK2-p53–independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells , 2011, Proceedings of the National Academy of Sciences.

[12]  M. DePristo,et al.  A framework for variation discovery and genotyping using next-generation DNA sequencing data , 2011, Nature Genetics.

[13]  A. Sparks,et al.  The mutation spectrum revealed by paired genome sequences from a lung cancer patient , 2010, Nature.

[14]  E. Birney,et al.  A small cell lung cancer genome reports complex tobacco exposure signatures , 2009, Nature.

[15]  Peter Dalgaard,et al.  R Development Core Team (2010): R: A language and environment for statistical computing , 2010 .

[16]  Heidi S Feiler,et al.  Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells. , 2009, Cancer research.

[17]  M. Stampfer,et al.  Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization. , 2009, Cancer research.

[18]  Brian H. Dunford-Shore,et al.  Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.

[19]  W. Foster,et al.  Quantification of benzo[a]pyrene and other PAHs in the serum and follicular fluid of smokers versus non-smokers. , 2008, Reproductive toxicology.

[20]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[21]  James H. Bullard,et al.  aroma.affymetrix: A generic framework in R for analyzing small to very large Affymetrix data sets in bounded memory , 2008 .

[22]  T. Tlsty,et al.  Inactivation of p53 Function in Cultured Human Mammary Epithelial Cells Turns the Telomere-Length Dependent Senescence Barrier from Agonescence into Crisis , 2007, Cell cycle.

[23]  G. Parmigiani,et al.  The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.

[24]  G. Peters,et al.  Regulation of the INK4b–ARF–INK4a tumour suppressor locus: all for one or one for all , 2006, Nature Reviews Molecular Cell Biology.

[25]  D. Scicchitano.  Transcription past DNA adducts derived from polycyclic aromatic hydrocarbons. , 2005, Mutation research.

[26]  K. Chin,et al.  In situ analyses of genome instability in breast cancer , 2004, Nature Genetics.

[27]  P. Yaswen,et al.  Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines , 2003, Oncogene.

[28]  S. Singletary.  Rating the Risk Factors for Breast Cancer , 2003, Annals of surgery.

[29]  N. Tretyakova,et al.  Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers , 2002, Oncogene.

[30]  L. Bernstein,et al.  Rapidly rising breast cancer incidence rates among Asian‐American women , 2002, International journal of cancer.

[31]  P. Yaswen,et al.  Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion , 2002, Oncogene.

[32]  Thea D. Tlsty,et al.  Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes , 2001, Nature.

[33]  A. Brenner,et al.  Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation , 1998, Oncogene.

[34]  M. Tang,et al.  Preferential Formation of Benzo[a]pyrene Adducts at Lung Cancer Mutational Hotspots in P53 , 1996, Science.

[35]  Donghui Li,et al.  Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology. , 1996, Cancer research.

[36]  A. Brenner,et al.  Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells. , 1995, Cancer research.

[37]  C. Greider,et al.  Developmental and tissue-specific regulation of mouse telomerase and telomere length. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[38]  F. Perera,et al.  Carcinogen-DNA adducts in human breast tissue. , 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[39]  A M Nomura,et al.  Migration patterns and breast cancer risk in Asian-American women. , 1993, Journal of the National Cancer Institute.

[40]  M. Stampfer,et al.  Chromosome analyses of human mammary epithelial cells at stages of chemical-induced transformation progression to immortality. , 1989, Cancer genetics and cytogenetics.

[41]  F. McCormick,et al.  Transformation of human mammary epithelial cells by oncogenic retroviruses. , 1988, Cancer research.

[42]  M. Stampfer,et al.  Human mammary epithelial cells in culture: differentiation and transformation. , 1988, Cancer treatment and research.

[43]  M. Stampfer,et al.  Factors influencing benzo[a]pyrene metabolism in human mammary epithelial cells in culture. , 1985, Carcinogenesis.

[44]  M. Stampfer,et al.  Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[45]  J. Bartholomew,et al.  Metabolism of Benzo(a)pyrene by Human Epithelial and Fibroblastic Cells: Metabolite Patterns and DNA Adduct Formation , 1982, Journal of cellular biochemistry.

[46]  H. Smith,et al.  Metabolism of benzo[a]pyrene by human mammary epithelial cells: toxicity and DNA adduct formation. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[47]  P. Buell.  Changing incidence of breast cancer in Japanese-American women. , 1973, Journal of the National Cancer Institute.