Abacavir prodrugs: microwave-assisted synthesis and their evaluation of anti-HIV activities.
暂无分享,去创建一个
[1] W H Oldendorf,et al. Lipid Solubility and Drug Penetration of the Blood Brain Barrier , 1974, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[2] H. Bundgaard,et al. Prodrugs of Peptides. 6. Bioreversible Derivatives of Thyrotropin-Releasing Hormone (TRH) with Increased Lipophilicity and Resistance to Cleavage by the TRH-Specific Serum Enzyme , 1990, Pharmaceutical Research.
[3] K. Agrawal,et al. Synthesis and biological evaluation of prodrugs of zidovudine. , 1990, Journal of medicinal chemistry.
[4] J. Sidtis,et al. The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. , 1988, Science.
[5] D. Jeffries,et al. Synthesis and anti-HIV evaluation of some phosphoramidate derivatives of AZT: studies on the effect of chain elongation on biological activity. , 1990, Antiviral research.
[6] H. Mitsuya,et al. Potential anti-AIDS drugs. Lipophilic, adenosine deaminase-activated prodrugs. , 1991, Journal of medicinal chemistry.
[7] P. Yogeeswari,et al. Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design. , 2005, Journal of medicinal chemistry.
[8] H. Bundgaard,et al. Kinetics and Pattern of Degradation of Thyrotropin-Releasing Hormone (TRH) in Human Plasma , 1990, Pharmaceutical Research.
[9] E. De Clercq,et al. Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency. , 2005, Journal of medicinal chemistry.
[10] P. Yogeeswari,et al. Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs. , 2005, European journal of medicinal chemistry.
[11] P. Yogeeswari,et al. Synthesis of stavudine amino acid ester prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS. , 2004, Bioorganic & medicinal chemistry letters.
[12] P. Yogeeswari,et al. Synthesis of zidovudine prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS. , 2005, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[13] M. Boyd,et al. New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity. , 1989, Journal of the National Cancer Institute.
[14] R. Schinazi,et al. Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine. , 1990, Journal of medicinal chemistry.