Family outbreaks of invasive community-associated methicillin-resistant Staphylococcus aureus infection.

Outbreaks of invasive methicillin-resistant Staphylococcus aureus infection within families are unusual. We investigated 2 family clusters of invasive methicillin-resistant Staphylococcus aureus infection, including 1 in which a young mother died of fulminant pneumonia. Although surveillance via culture of family contacts of patients with invasive methicillin-resistant Staphylococcus aureus infection is not currently recommended, such clusters should stimulate reevaluation of preventive measures.

[1]  Fred C Tenover,et al.  Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002. , 2006, The Journal of infectious diseases.

[2]  Patchen Dellinger,et al.  Practice guidelines for the diagnosis and management of skin and soft-tissue infections. , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  K. Edwards,et al.  Increasing Rates of Nasal Carriage of Methicillin-Resistant Staphylococcus aureus in Healthy Children , 2005, The Pediatric infectious disease journal.

[4]  William R Bishai,et al.  Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. , 2005, The Lancet. Infectious diseases.

[5]  R. Lynfield,et al.  Methicillin-resistant Staphylococcus aureus disease in three communities. , 2005, The New England journal of medicine.

[6]  W. Huskins,et al.  Controlling meticillin-resistant Staphylococcus aureus, aka “Superbug” , 2005, The Lancet.

[7]  J. Wagenvoort,et al.  Transmission of methicillin-resistantStaphylococcus aureus within a household , 1997, European Journal of Clinical Microbiology and Infectious Diseases.

[8]  Mian Cai,et al.  Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[9]  M. Joly-Guillou,et al.  Carriage of Methicillin-Resistant Staphylococcus aureus Among Hospital Employees: Prevalence, Duration, and Transmission to Households , 2004, Infection Control & Hospital Epidemiology.

[10]  C. Salgado,et al.  Community-acquired methicillin-resistant Staphylococcus aureus. , 2004, JAMA.

[11]  D. Toney,et al.  Spread of Methicillin-Resistant Staphylococcus aureus (MRSA) Among Household Contacts of Individuals With Nosocomially Acquired MRSA , 2003, Infection Control & Hospital Epidemiology.

[12]  L. Saiman,et al.  Nosocomial transmission of methicillin-resistant Staphylococcus aureus from a mother to her preterm quadruplet infants. , 2002, American journal of infection control.

[13]  J. Boyce MRSA patients: proven methods to treat colonization and infection. , 2001, The Journal of hospital infection.

[14]  Gina Pugliese,et al.  Nasal Carriage as a Source of Staphylococcus aureus Bacteremia , 2001, Infection Control & Hospital Epidemiology.

[15]  J. Lucet,et al.  Community-acquired methicillin-resistant Staphylococcus aureus and familial transmission. , 1999, JAMA.

[16]  J. Bartlett,et al.  GUIDELINES FROM THE INFECTIOUS DISEASES SOCIETY OF AMERICA Community-Acquired Pneumonia in Adults: Guidelines for Management , 1998 .

[17]  J. Anson,et al.  Staff carriage of methicillin-resistant Staphylococcus aureus (EMRSA 15) and the home environment: a case report. , 1997, The Journal of hospital infection.

[18]  J. Anderson,et al.  Family infection with methicillin-resistant Staphylococcus aureus , 1995, The Lancet.

[19]  B. Doebbeling,et al.  Familial carriage of methicillin-resistant Staphylococcus aureus and subsequent infection in a premature neonate. , 1995, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.