Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease

[1]  J. Csernansky,et al.  Corticosterone and related receptor expression are associated with increased β-amyloid plaques in isolated Tg2576 mice , 2008, Neuroscience.

[2]  J. Donnelly,et al.  Cardiorespiratory fitness and brain atrophy in early Alzheimer disease , 2008, Neurology.

[3]  Guojun Bu,et al.  Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo , 2008, Neuron.

[4]  C. Cotman,et al.  Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid , 2008, Journal of Neuroinflammation.

[5]  C. Cotman,et al.  Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition , 2008, Neurobiology of Disease.

[6]  C. Cotman,et al.  Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse , 2007, Behavioural Brain Research.

[7]  D. Holtzman,et al.  Acute stress increases interstitial fluid amyloid-β via corticotropin-releasing factor and neuronal activity , 2007, Proceedings of the National Academy of Sciences.

[8]  Áine M. Kelly,et al.  The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial- and non-spatial learning , 2007, Behavioural Brain Research.

[9]  Ichiro Kita,et al.  Effects of spontaneous and forced running on activation of hypothalamic corticotropin-releasing hormone neurons in rats. , 2007, Life sciences.

[10]  A. Starkweather.  The Effects of Exercise on Perceived Stress and IL-6 Levels Among Older Adults , 2007, Biological research for nursing.

[11]  A. Blankenship,et al.  Cognitive and Physical Activity Differently Modulate Disease Progression in the Amyloid Precursor Protein (APP)-23 Model of Alzheimer’s Disease , 2006, Biological Psychiatry.

[12]  B. McEwen,et al.  Protective and damaging effects of stress mediators: central role of the brain , 2006, Dialogues in clinical neuroscience.

[13]  A. Fagan,et al.  Plasma Cortisol and Progression of Dementia in DAT Subjects , 2006 .

[14]  A. Fagan,et al.  Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia. , 2006, The American journal of psychiatry.

[15]  P. Wong,et al.  Alterations in spatial learning and memory after forced exercise , 2006, Brain Research.

[16]  D. Bennett,et al.  Chronic Psychological Distress and Risk of Alzheimer’s Disease in Old Age , 2006, Neuroepidemiology.

[17]  D. Albeck,et al.  Mild forced treadmill exercise enhances spatial learning in the aged rat , 2006, Behavioural Brain Research.

[18]  Barry E. Levin,et al.  Neurobiology of Exercise , 2006 .

[19]  Li Wang,et al.  Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older , 2006, Annals of Internal Medicine.

[20]  Joseph P Huston,et al.  Episodic-like memory in mice: simultaneous assessment of object, place and temporal order memory. , 2005, Brain research. Brain research protocols.

[21]  B. Winblad,et al.  Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease , 2005, The Lancet Neurology.

[22]  D. Borchelt,et al.  Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.

[23]  Victoria M Perreau,et al.  Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.

[24]  Lewis H Kuller,et al.  Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. , 2005, American journal of epidemiology.

[25]  J. Csernansky,et al.  Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer’s disease , 2005, Psychopharmacology.

[26]  Ilana S. Hairston,et al.  Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice , 2005, Cell.

[27]  D. Bennett,et al.  Proneness to psychological distress and risk of Alzheimer disease in a biracial community , 2005, Neurology.

[28]  J. Csernansky,et al.  Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress , 2004, Neuroscience.

[29]  Zhe Ying,et al.  Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition , 2004, The European journal of neuroscience.

[30]  J. Trojanowski,et al.  Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis , 2004, Journal of Neuroinflammation.

[31]  H. Potter,et al.  Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable &bgr;-amyloid deposition , 2004, Neuroreport.

[32]  Fulvio Alexandre Scorza,et al.  Differential effects of spontaneous versus forced exercise in rats on the staining of parvalbumin-positive neurons in the hippocampal formation , 2004, Neuroscience Letters.

[33]  Laura Fratiglioni,et al.  Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease. , 2004, American journal of epidemiology.

[34]  J. Schneider,et al.  Proneness to psychological distress is associated with risk of Alzheimer’s disease , 2003, Neurology.

[35]  H. Buschke,et al.  Leisure activities and the risk of dementia in the elderly. , 2003, The New England journal of medicine.

[36]  A. Kramer,et al.  Fitness Effects on the Cognitive Function of Older Adults , 2003, Psychological science.

[37]  C. Cotman,et al.  Exercise: a behavioral intervention to enhance brain health and plasticity , 2002, Trends in Neurosciences.

[38]  G. Arendash,et al.  Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months , 2002, Physiology & Behavior.

[39]  George A. Carlson,et al.  The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease , 2002, The Journal of Neuroscience.

[40]  E. R. Kloet,et al.  Repeated exposure to rats has persistent genotype-dependent effects on learning and locomotor activity of apolipoprotein E knockout and C57Bl/6 mice , 2001, Behavioural Brain Research.

[41]  M. Skalicky,et al.  Voluntary and forced exercise influence the survival and body composition of ageing male rats differently , 2001, Experimental Gerontology.

[42]  George Paxinos,et al.  The Mouse Brain in Stereotaxic Coordinates , 2001 .

[43]  Virginia M. Y. Lee,et al.  Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis , 2001, The Journal of Neuroscience.

[44]  J. Lindsay,et al.  Physical activity and risk of cognitive impairment and dementia in elderly persons. , 2001, Archives of neurology.

[45]  Mikio Shoji,et al.  Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease , 2001, The Journal of Neuroscience.

[46]  Bruce S. McEwen,et al.  The neurobiology of stress: from serendipity to clinical relevance. , 2000, Brain research.

[47]  J. Guralnik,et al.  Documented head injury in early adulthood and risk of Alzheimer’s disease and other dementias , 2000, Neurology.

[48]  T J Sejnowski,et al.  Running enhances neurogenesis, learning, and long-term potentiation in mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[49]  K. Krishnan,et al.  Effects of exercise training on older patients with major depression. , 1999, Archives of internal medicine.

[50]  F. Gage,et al.  Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus , 1999, Nature Neuroscience.

[51]  D Commenges,et al.  Are sex and educational level independent predictors of dementia and Alzheimer’s disease? Incidence data from the PAQUID project , 1999, Journal of neurology, neurosurgery, and psychiatry.

[52]  L. Waite,et al.  Health habits and risk of cognitive impairment and dementia in old age: A prospective study on the effects of exercise, smoking and alcohol consumption , 1998, Australian and New Zealand journal of public health.

[53]  S. Younkin,et al.  Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice , 1996, Science.

[54]  D R Wekstein,et al.  Linguistic ability in early life and cognitive function and Alzheimer's disease in late life. Findings from the Nun Study. , 1996, JAMA.

[55]  B. McEwen,et al.  Stress and cognitive function , 1995, Current Opinion in Neurobiology.

[56]  C. Cotman,et al.  Exercise and brain neurotrophins , 1995, Nature.

[57]  W. Stummer,et al.  Reduced Mortality and Brain Damage After Locomotor Activity in Gerbil Forebrain Ischemia , 1994, Stroke.

[58]  W. Greenough,et al.  Usual vs. successful aging: Some notes on experiential factors , 1991, Neurobiology of Aging.

[59]  R. Sapolsky.  Glucocorticoid toxicity in the hippocampus: Temporal aspects of neuronal vulnerability , 1985, Brain Research.

[60]  J. Birren,et al.  Aging, brain damage, and psychomotor slowing. , 1970, Psychological bulletin.

[61]  W. Haskell,et al.  Physical activity and the prevention of coronary heart disease. , 1968, Bulletin of the New York Academy of Medicine.

[62]  M. Mintun,et al.  Brain volume decline in aging: evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve. , 2008, Archives of neurology.

[63]  J. Douglas Bremner,et al.  Does stress damage the brain? , 1999, Biological Psychiatry.

[64]  Arthur F. Kramer,et al.  Neurocognitive aging and cardiovascular fitness , 2007, Journal of Molecular Neuroscience.

[65]  R. Dishman.  Brain monoamines, exercise, and behavioral stress: animal models. , 1997, Medicine and science in sports and exercise.

[66]  J. Merlie,et al.  Transgene detection in unpurified mouse tail DNA by polymerase chain reaction. , 1991, BioTechniques.

[67]  R. Sapolsky.  Chapter 2 Glucocorticoids, hippocampal damage and the glutamatergic synapse , 1990 .