An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis

[1]  V. Wiwanitkit,et al.  Congenital Zika virus infection in twin pregnancies. , 2017, Arquivos de Neuro-Psiquiatria.

[2]  F. Tovar-Moll,et al.  Congenital Zika Virus Infection: Beyond Neonatal Microcephaly. , 2017, JAMA neurology.

[3]  Alex A. Pollen,et al.  Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. , 2017, Cell stem cell.

[4]  F. Müller,et al.  An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome. , 2017, Cell reports.

[5]  R. Hevner,et al.  C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus , 2017, The Journal of Neuroscience.

[6]  Ken’ya Furuta,et al.  Katanin p80, NuMA and cytoplasmic dynein cooperate to control microtubule dynamics , 2017, Scientific Reports.

[7]  H. Okano,et al.  Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines , 2016, Molecular Brain.

[8]  A. Chédotal,et al.  Slit-Robo signaling , 2016, Development.

[9]  W. Dobyns,et al.  Genetic Basis of Brain Malformations , 2016, Molecular Syndromology.

[10]  H. Okano,et al.  In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations , 2016, Molecular Brain.

[11]  S. Heilshorn,et al.  Matrix interactions modulate neurotrophin-mediated neurite outgrowth and pathfinding , 2015, Neural regeneration research.

[12]  Davide Heller,et al.  STRING v10: protein–protein interaction networks, integrated over the tree of life , 2014, Nucleic Acids Res..

[13]  J. Johansson,et al.  Spider silk for xeno-free long-term self-renewal and differentiation of human pluripotent stem cells. , 2014, Biomaterials.

[14]  M. R. Costa,et al.  Proliferative Defects and Formation of a Double Cortex in Mice Lacking Mltt4 and Cdh2 in the Dorsal Telencephalon , 2014, The Journal of Neuroscience.

[15]  A. Fry,et al.  The genetics of lissencephaly , 2014, American journal of medical genetics. Part C, Seminars in medical genetics.

[16]  A. Wynshaw-Boris,et al.  LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. , 2014, Human molecular genetics.

[17]  K. Flynn The cytoskeleton and neurite initiation , 2013, Bioarchitecture.

[18]  Yun-Tai Kim,et al.  Slit2 Inactivates GSK3β to Signal Neurite Outgrowth Inhibition , 2012, PloS one.

[19]  J. Loturco,et al.  Increasing Doublecortin Expression Promotes Migration of Human Embryonic Stem Cell‐Derived Neurons , 2012, Stem cells.

[20]  P. Arlotta,et al.  A Radial Glia-Specific Role of RhoA in Double Cortex Formation , 2012, Neuron.

[21]  K. Tago,et al.  Phosphorylation of Doublecortin by Protein Kinase A Orchestrates Microtubule and Actin Dynamics to Promote Neuronal Progenitor Cell Migration* , 2012, The Journal of Biological Chemistry.

[22]  Matthew Trotter,et al.  Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons , 2012, PloS one.

[23]  Bernhard M. Schuldt,et al.  A bioinformatic assay for pluripotency in human cells , 2011, Nature Methods.

[24]  H. Nakauchi,et al.  Development of Defective and Persistent Sendai Virus Vector , 2010, The Journal of Biological Chemistry.

[25]  Joshua Barry,et al.  Polarized targeting of L1‐CAM regulates axonal and dendritic bundling in vitro , 2010, The European journal of neuroscience.

[26]  K. Mori,et al.  Essential Roles of Notch Signaling in Maintenance of Neural Stem Cells in Developing and Adult Brains , 2010, The Journal of Neuroscience.

[27]  M. Killeen,et al.  Netrin, Slit and Wnt receptors allow axons to choose the axis of migration. , 2008, Developmental biology.

[28]  T. Deerinck,et al.  Spinophilin Facilitates Dephosphorylation of Doublecortin by PP1 to Mediate Microtubule Bundling at the Axonal Wrist , 2007, Cell.

[29]  Carolyn A Moores,et al.  Distinct roles of doublecortin modulating the microtubule cytoskeleton , 2006, The EMBO journal.

[30]  G. Eichele,et al.  Neurabin II mediates doublecortin-dephosphorylation on actin filaments. , 2006, Biochemical and biophysical research communications.

[31]  C. Walsh,et al.  Genetic Interactions between Doublecortin and Doublecortin-like Kinase in Neuronal Migration and Axon Outgrowth , 2006, Neuron.

[32]  A. Kriegstein,et al.  LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages , 2005, The Journal of cell biology.

[33]  Hiroaki Kitano,et al.  The PANTHER database of protein families, subfamilies, functions and pathways , 2004, Nucleic Acids Res..

[34]  Ronald A Milligan,et al.  Mechanism of microtubule stabilization by doublecortin. , 2004, Molecular cell.

[35]  W. Dobyns,et al.  X-Linked Lissencephaly With Abnormal Genitalia as a Tangential Migration Disorder Causing Intractable Epilepsy: Proposal for a New Term, “Interneuronopathy” , 2004, Journal of child neurology.

[36]  R. Ramos,et al.  RNAi reveals doublecortin is required for radial migration in rat neocortex , 2003, Nature Neuroscience.

[37]  M. Campbell,et al.  PANTHER: a library of protein families and subfamilies indexed by function. , 2003, Genome research.

[38]  C. Walsh,et al.  The DCX-domain tandems of doublecortin and doublecortin-like kinase , 2003, Nature Structural Biology.

[39]  K. Kizhatil,et al.  A New Activity of Doublecortin in Recognition of the Phospho-FIGQY Tyrosine in the Cytoplasmic Domain of Neurofascin , 2002, The Journal of Neuroscience.

[40]  C. Walsh,et al.  Doublecortin Is Required in Mice for Lamination of the Hippocampus But Not the Neocortex , 2002, The Journal of Neuroscience.

[41]  D. van der Kooy,et al.  Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. , 2002, Genes & development.

[42]  C. Schuurmans,et al.  Molecular mechanisms underlying cell fate specification in the developing telencephalon , 2002, Current Opinion in Neurobiology.

[43]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[44]  D. Ledbetter,et al.  LIS1: from cortical malformation to essential protein of cellular dynamics , 2001, Trends in Neurosciences.

[45]  U. Rutishauser,et al.  Roles, regulation, and mechanism of polysialic acid function during neural development. , 2001, Biochimie.

[46]  G. Fishell,et al.  Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors. , 2001, Development.

[47]  C. Walsh,et al.  Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations , 2000, Nature Genetics.

[48]  S. Pietrokovski,et al.  Doublecortin mutations cluster in evolutionarily conserved functional domains. , 2000, Human molecular genetics.

[49]  G. Meyer,et al.  Embryonic and Early Fetal Development of the Human Neocortex , 2000, The Journal of Neuroscience.

[50]  M. Tessier-Lavigne,et al.  Slit proteins: key regulators of axon guidance, axonal branching, and cell migration , 2000, Current Opinion in Neurobiology.

[51]  S. Mcconnell,et al.  Doublecortin Is a Developmentally Regulated, Microtubule-Associated Protein Expressed in Migrating and Differentiating Neurons , 1999, Neuron.

[52]  C. Walsh,et al.  Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons , 1999, Neuron.

[53]  Y. Berwald‐Netter,et al.  A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome , 1998, Cell.

[54]  I. Scheffer,et al.  doublecortin , a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein , 1998, Cell.

[55]  I. Scheffer,et al.  Linkage and physical mapping of X-linked lissencephaly/SBH (XLIS): a gene causing neuronal migration defects in human brain. , 1997, Human molecular genetics.

[56]  D. Friedlander,et al.  The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth , 1994, The Journal of cell biology.

[57]  P. Rakić Mode of cell migration to the superficial layers of fetal monkey neocortex , 1972, The Journal of comparative neurology.

[58]  pFahad Alsufayanp Repurposing common Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) could potentially reverse intrinsic drug resistance in superbugs , 2018 .

[59]  Shuang Song Brigham and Women's Hospital/Harvard Medical School , 2011 .

[60]  M. Schachner,et al.  Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration , 2006, Nature Neuroscience.

[61]  田中 輝幸 Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration , 2005 .

[62]  P. Maness Nonreceptor protein tyrosine kinases associated with neuronal development. , 1992, Developmental neuroscience.

[63]  C. Shores,et al.  Localization of the normal cellular src protein to the growth cone of differentiating neurons in brain and retina. , 1990, Advances in experimental medicine and biology.