Calcium signalling in lymphocyte activation and disease
暂无分享,去创建一个
[1] S. Feske,et al. The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells , 2007, The Journal of Immunology.
[2] Rebecca R. Boyles,et al. Calcium Inhibition and Calcium Potentiation of Orai1, Orai2, and Orai3 Calcium Release-activated Calcium Channels* , 2007, Journal of Biological Chemistry.
[3] Y. Gwack,et al. Biochemical and Functional Characterization of Orai Proteins* , 2007, Journal of Biological Chemistry.
[4] Tobias Meyer,et al. Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion , 2007, Proceedings of the National Academy of Sciences.
[5] R. Penner,et al. CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca2+ Channels with Distinct Functional Properties , 2007, Current Biology.
[6] Richard S Lewis,et al. The molecular choreography of a store-operated calcium channel , 2007, Nature.
[7] R. Tsien,et al. A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure , 2007, Proceedings of the National Academy of Sciences.
[8] Peter Lipp,et al. Sustained Activity of Calcium Release-activated Calcium Channels Requires Translocation of Mitochondria to the Plasma Membrane* , 2006, Journal of Biological Chemistry.
[9] B. Grimbacher,et al. Common variable immunodeficiency: The power of co-stimulation. , 2006, Seminars in immunology.
[10] M. Iino,et al. Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum , 2006, Proceedings of the National Academy of Sciences.
[11] J. Billingsley,et al. CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel , 2006, Current Biology.
[12] R. Flavell,et al. Critical role for the β regulatory subunits of Cav channels in T lymphocyte function , 2006, Proceedings of the National Academy of Sciences.
[13] Y. Gwack,et al. Orai1 is an essential pore subunit of the CRAC channel , 2006, Nature.
[14] Shenyuan L. Zhang,et al. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai , 2006, Nature.
[15] JoAnn Buchanan,et al. The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions , 2006, The Journal of cell biology.
[16] JoAnn Buchanan,et al. Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane , 2006, The Journal of cell biology.
[17] A. Pugh-Bernard,et al. B cell receptor signaling in human systemic lupus erythematosus , 2006, Current opinion in rheumatology.
[18] Rebecca R. Boyles,et al. Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1* , 2006, Journal of Biological Chemistry.
[19] J. Soboloff,et al. Orai1 and STIM Reconstitute Store-operated Calcium Channel Function* , 2006, Journal of Biological Chemistry.
[20] J. Soboloff,et al. STIM2 Is an Inhibitor of STIM1-Mediated Store-Operated Ca2+ Entry , 2006, Current Biology.
[21] X. Zhang,et al. Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[22] M. Nadler,et al. Amplification of CRAC current by STIM1 and CRACM1 (Orai1) , 2006, Nature Cell Biology.
[23] J. Kinet,et al. CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry , 2006, Science.
[24] Bogdan Tanasa,et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function , 2006, Nature.
[25] M. van der Burg,et al. An antibody-deficiency syndrome due to mutations in the CD19 gene. , 2006, The New England journal of medicine.
[26] J. Soboloff,et al. STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[27] B. Freedman,et al. The WAVE2 Complex Regulates Actin Cytoskeletal Reorganization and CRAC-Mediated Calcium Entry during T Cell Activation , 2006, Current Biology.
[28] R. Geha,et al. Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome. , 2005, The Journal of allergy and clinical immunology.
[29] S. Gauld,et al. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling , 2005, Nature Immunology.
[30] T. Deerinck,et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane , 2005, Nature.
[31] S. Feske,et al. A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients , 2005, The Journal of experimental medicine.
[32] Tobias Meyer,et al. STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx , 2005, Current Biology.
[33] F. Macian,et al. NFAT proteins: key regulators of T-cell development and function , 2005, Nature Reviews Immunology.
[34] R. Carter,et al. CD19 regulates B cell maturation, proliferation, and positive selection in the FDC zone of murine splenic germinal centers. , 2005, Immunity.
[35] S. Wagner,et al. STIM1, an essential and conserved component of store-operated Ca2+ channel function , 2005, The Journal of cell biology.
[36] H. Ochs,et al. The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-κB (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement , 2005, The Journal of Immunology.
[37] A. Nomeir,et al. Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice , 2005, European journal of immunology.
[38] J. Putney,et al. Store-operated calcium channels. , 2005, Physiological reviews.
[39] H. Fuchs,et al. Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry. , 2005, Immunity.
[40] H. Ochs,et al. The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-κB (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement1 , 2005, The Journal of Immunology.
[41] D. Oh,et al. Calcium oscillations regulate thymocyte motility during positive selection in the three-dimensional thymic environment , 2005, Nature Immunology.
[42] J. Casanova,et al. Primary immunodeficiency diseases: an update. , 2004, The Journal of allergy and clinical immunology.
[43] A. Rao,et al. E3 Ligases in T Cell Anergy—Turning Immune Responses into Tolerance , 2004, Science's STKE.
[44] Michael Pennington,et al. K+ channels as targets for specific immunomodulation. , 2004, Trends in pharmacological sciences.
[45] Joseph Heitman,et al. Calcineurin: a central controller of signalling in eukaryotes , 2004, EMBO reports.
[46] R. Buckley. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. , 2004, Annual review of immunology.
[47] Michael Loran Dustin,et al. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins , 2004, Nature Immunology.
[48] A. Trautmann,et al. Ca2+ signals and T lymphocytes “New mechanisms and functions in Ca2+ signalling” , 2004, Biology of the cell.
[49] David E. Clapham,et al. The mitochondrial calcium uniporter is a highly selective ion channel , 2004, Nature.
[50] E. Mccleskey,et al. Permeation and selectivity in calcium channels. , 2003, Annual review of physiology.
[51] H. Okamura,et al. Ca2+/calcineurin signalling in cells of the immune system. , 2003, Biochemical and biophysical research communications.
[52] T. Nomura,et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice , 2003, Nature.
[53] Lin Chen,et al. Transcriptional regulation by calcium, calcineurin, and NFAT. , 2003, Genes & development.
[54] J. Neilson,et al. Calcium signalling in lymphocytes. , 2003, Current opinion in immunology.
[55] Richard S Lewis,et al. CRAC channels: activation, permeation, and the search for a molecular identity. , 2003, Cell calcium.
[56] Gillian M. Griffiths,et al. Delivering the kiss of death , 2003, Nature Immunology.
[57] L. Atherly,et al. The role of Tec family kinases in T cell development and function , 2003, Immunological reviews.
[58] M. Seman,et al. Cutting Edge: A Natural P451L Mutation in the Cytoplasmic Domain Impairs the Function of the Mouse P2X7 Receptor1 , 2002, The Journal of Immunology.
[59] Ash A. Alizadeh,et al. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[60] D. Clapham. Sorting out MIC, TRP, and CRAC Ion Channels , 2002, The Journal of general physiology.
[61] C. Gabel,et al. Absence of the P2X7 Receptor Alters Leukocyte Function and Attenuates an Inflammatory Response , 2002, The Journal of Immunology.
[62] Anjana Rao,et al. Transcriptional Mechanisms Underlying Lymphocyte Tolerance , 2002, Cell.
[63] M. Hoth,et al. Enhancement of calcium signalling dynamics and stability by delayed modulation of the plasma‐membrane calcium‐ATPase in human T cells , 2002, The Journal of physiology.
[64] R. Williams,et al. Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation. , 2002, Biochimica et biophysica acta.
[65] M. Iino,et al. Transient Receptor Potential 1 Regulates Capacitative Ca2+ Entry and Ca2+ Release from Endoplasmic Reticulum in B Lymphocytes 〉 , 2002, The Journal of experimental medicine.
[66] B. Bierer,et al. Identification of Novel Targets of Immunosuppressive Agents by cDNA-based Microarray Analysis* , 2002, The Journal of Biological Chemistry.
[67] R. Penner,et al. CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties* , 2001, The Journal of Biological Chemistry.
[68] T. Tedder,et al. CD19 Amplification of B Lymphocyte Ca2+ Responses , 2001, The Journal of Biological Chemistry.
[69] K. Chandy,et al. Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[70] A. Zweifach,et al. Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing. , 2001, Immunity.
[71] M. Nambiar,et al. Defective FcγRIIb1 signaling contributes to enhanced calcium response in B cells from patients with systemic lupus erythematosus , 2001 .
[72] Richard S Lewis,et al. Potentiation and inhibition of Ca2+ release‐activated Ca2+ channels by 2‐aminoethyldiphenyl borate (2‐APB) occurs independently of IP3 receptors , 2001, The Journal of physiology.
[73] K. Haas,et al. CD19-CD21 complex regulates an intrinsic Src family kinase amplification loop that links innate immunity with B-lymphocyte intracellular calcium responses. , 2001, Biochemical Society transactions.
[74] Philip Smith,et al. Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins. , 2001, The Biochemical journal.
[75] K. Chandy,et al. Molecular Properties and Physiological Roles of Ion Channels in the Immune System , 2001, Journal of Clinical Immunology.
[76] D. Clapham,et al. Fundamental Ca2+ Signaling Mechanisms in Mouse Dendritic Cells: CRAC Is the Major Ca2+ Entry Pathway , 2001, The Journal of Immunology.
[77] D. Clapham,et al. CaT1 manifests the pore properties of the calcium-release-activated calcium channel , 2001, Nature.
[78] Anjana Rao,et al. Gene regulation mediated by calcium signals in T lymphocytes , 2001, Nature Immunology.
[79] A. Parekh,et al. An examination of the secretion‐like coupling model for the activation of the Ca2+ release‐activated Ca2+ current ICRAC in RBL‐1 cells , 2001, The Journal of physiology.
[80] Beverly H. Koller,et al. Altered Cytokine Production in Mice Lacking P2X7Receptors* , 2001, The Journal of Biological Chemistry.
[81] Philip Smith,et al. STIM1: a novel phosphoprotein located at the cell surface. , 2000, Biochimica et biophysica acta.
[82] J. Ravetch,et al. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. , 2000, Immunity.
[83] T. Kurosaki,et al. Regulation of the phospholipase C‐γ2 pathway in B cells , 2000, Immunological reviews.
[84] R. Tsien,et al. Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger , 1999, Cell.
[85] R. Patterson,et al. Store-Operated Ca2+ Entry Evidence for a Secretion-like Coupling Model , 1999, Cell.
[86] K. Bottomly,et al. Regulation of naive T cell differentiation by varying the potency of TCR signal transduction. , 1999, Seminars in immunology.
[87] D. Rawlings. Bruton's tyrosine kinase controls a sustained calcium signal essential for B lineage development and function. , 1999, Clinical immunology.
[88] L. Samelson,et al. T cell antigen-receptor signal transduction. , 1999, Current opinion in immunology.
[89] M. Neuberger,et al. Deficiency in CD22, a B Cell–specific Inhibitory Receptor, Is Sufficient to Predispose to Development of High Affinity Autoantibodies , 1999, The Journal of experimental medicine.
[90] J. Kinet,et al. Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1 , 1999, Oncogene.
[91] Eric O Long,et al. Essential role of LAT in T cell development. , 1999, Immunity.
[92] P. Rogers,et al. High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. , 1998, Journal of immunology.
[93] F. Alt,et al. Impaired Viability and Profound Block in Thymocyte Development in Mice Lacking the Adaptor Protein SLP-76 , 1998, Cell.
[94] S. Eliason,et al. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. , 1998, Science.
[95] R. Zinkernagel,et al. Antiviral Protection and Germinal Center Formation, But Impaired B Cell Memory in the Absence of CD19 , 1998, The Journal of experimental medicine.
[96] S. Bunnell,et al. T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells , 1998, The Journal of experimental medicine.
[97] T. Kurosaki,et al. Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)–mediated Inhibitory Signal , 1998, The Journal of experimental medicine.
[98] H. Ochs,et al. Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B‐cell receptor activation , 1998, The EMBO journal.
[99] M. Cooper,et al. The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[100] A. Trautmann,et al. Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response , 1998, European journal of immunology.
[101] C. Croce,et al. GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development. , 1997, Cancer research.
[102] P. Allen,et al. Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype. , 1997, Journal of immunology.
[103] D. Greiner,et al. Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency. , 1997, Trends in biotechnology.
[104] J. Cambier,et al. Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation. , 1997, Immunity.
[105] Christopher C. Goodnow,et al. Differential activation of transcription factors induced by Ca2+ response amplitude and duration , 1997, Nature.
[106] R. Perlmutter,et al. CD22 regulates thymus-independent responses and the lifespan of B cells , 1996, Nature.
[107] G. Tsokos,et al. B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. , 1996, The Journal of clinical investigation.
[108] A. Miller,et al. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. , 1996, Immunity.
[109] M. Neuberger,et al. Hyperresponsive B Cells in CD22-Deficient Mice , 1996, Science.
[110] S. Feske,et al. Severe combined immunodeficiency due to defective binding of the nuclear factor of activated T cells in T lymphocytes of two male siblings , 1996, European journal of immunology.
[111] K. Oritani,et al. Identification of stromal cell products that interact with pre-B cells , 1996, The Journal of cell biology.
[112] T. Kurosaki,et al. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2 , 1996, The Journal of experimental medicine.
[113] P. Negulescu,et al. Polarity of T cell shape, motility, and sensitivity to antigen. , 1996, Immunity.
[114] D. Littman,et al. Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. , 1995, Immunity.
[115] A. Woodard,et al. Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells , 1995, The Journal of experimental medicine.
[116] G. Crabtree,et al. Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels , 1995, The Journal of cell biology.
[117] S. Stacker,et al. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease , 1995, Cell.
[118] A. Fischer,et al. A primary T-cell immunodeficiency associated with defective transmembrane calcium influx. , 1995, Blood.
[119] H. Korn,et al. The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. , 1994, The Journal of biological chemistry.
[120] J. Litzman,et al. A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency. , 1994, Blood.
[121] M. Nussenzweig,et al. A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling , 1994, Nature.
[122] M. Nussenzweig,et al. A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling , 1994, Nature.
[123] D. Fruman,et al. Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. , 1993, Current opinion in immunology.
[124] Roger Y. Tsien,et al. Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx , 1993, Nature.
[125] R. Lewis,et al. Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[126] G. Mills,et al. Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome. , 1992, The Journal of clinical investigation.
[127] D. Fearon,et al. CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. , 1992, Science.
[128] R. Penner,et al. Depletion of intracellular calcium stores activates a calcium current in mast cells , 1992, Nature.
[129] T. Gajewski,et al. Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones. , 1990, Journal of immunology.
[130] R Y Tsien,et al. Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets. , 1987, The EMBO journal.
[131] J. Putney,et al. A model for receptor-regulated calcium entry. , 1986, Cell calcium.
[132] A. Weiss,et al. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[133] P. Goodford,et al. Increased uptake of calcium by human lymphocytes treated with phytohaemagglutinin. , 1970, The Journal of physiology.
[134] J. Whitfield,et al. The role of calcium in the mitotic stimulation of rat thymocytes by detergents, agmatine and poly-L-lysine. , 1968, Experimental cell research.
[135] B. Nilius,et al. Structure-function relationship of the TRP channel superfamily. , 2006, Reviews of physiology, biochemistry and pharmacology.
[136] G. Crabtree,et al. Lymphocyte calcium signaling from membrane to nucleus , 2005, Nature Immunology.
[137] Tobias Meyer,et al. STIM Is a Ca 2+ Sensor Essential for Ca 2+ -Store-Depletion-Triggered Ca 2+ Influx , 2005 .
[138] Richard S Lewis,et al. Calcium signaling mechanisms in T lymphocytes. , 2001, Annual review of immunology.
[139] T. Tedder,et al. CD19 Amplification of B Lymphocyte Ca 2 (cid:1) Responses A ROLE FOR Lyn SEQUESTRATION IN EXTINGUISHING NEGATIVE REGULATION* , 2001 .
[140] H. Fehling,et al. Structure and function of the pre-T cell receptor. , 1997, Annual review of immunology.