Antiurolithiatic activity of aqueous extract of bark of moringa oleifera (lam.) in rats

In the present study, aqueous extract of bark of Moringa oleifera administered orally, was eva- luated for its antiurolithiatic potential in albino rats of Wistar strains. The stones were produced in this study by zinc disc foreign body insertion in the bladder supplemented with 1% ethylene glycol in drinking water. The reduction in weight of the stones was used as criteria for assessing the preventive or curative antiurolithiatic effect of the bark of this plant. Two doses of extract for prophylactic and curative groups were used. In both groups the oral administration of the extract of bark of Moringa oleifera has resulted in significant reduction in the weight of bladder stones compared to the control group.

[1]  D. Sujatha,et al.  Herbal Drugs in Urolithiasis - A Review , 2007 .

[2]  M. Meng,et al.  Urinary Stone Disease , 2007 .

[3]  M. Brown,et al.  Rat Strains Differ in Susceptibility to Ureaplasma parvum-Induced Urinary Tract Infection and Struvite Stone Formation , 2006, Infection and Immunity.

[4]  R. Karadi,et al.  Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats. , 2006, Journal of ethnopharmacology.

[5]  O. Moe,et al.  Kidney stones: pathophysiology and medical management , 2006, The Lancet.

[6]  J. Fahey,et al.  Moringa oleifera: A Review of the Medical Evidence for Its Nutritional, Therapeutic, and Prophylactic Properties. Part 1. , 2005 .

[7]  R. Pérez,et al.  Antiurolithiatic Activity of Salix taxifolia Aqueous Extract , 2002 .

[8]  An,et al.  Effect Of Moringa Oleifera Lam On Paracetamol - Induced Hepatotoxicity , 1998 .

[9]  A. L. Udupa,et al.  A comparative study on the effect of some indigenous drugs on normal and steroid-depressed healing , 1998 .

[10]  F. Shode,et al.  Antiinflammatory effects of Moringa oleifera root extract , 1996 .

[11]  M. Uy,et al.  Anti-inflammatory and antitumor activities of seed extracts of malunggay, Moringa oleifera L. (Moringaceae) , 1996 .

[12]  A. Gilani,et al.  Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. , 1995, Phytochemistry.

[13]  Arya Vaidya Sala Indian medicinal plants : a compendium of 500 species , 1994 .

[14]  A. L. Udupa,et al.  Studies on the anti-inflammatory and wound healing properties of Moringa oleifera and Aegle marmelos , 1994 .

[15]  P. K. Warrier,et al.  Indian Medicinal Plants: A Compendium of 500 Species , 1993 .

[16]  A. Cáceres,et al.  Pharmacologic properties of Moringa oleifera. 2: Screening for antispasmodic, antiinflammatory and diuretic activity. , 1992, Journal of ethnopharmacology.

[17]  S. Shukla,et al.  PRE AND POST-IMPLANTATION CHANGES IN THE UTEUS OF RATS: RESPONSE TO MORINGA OLEIFERA LAM. EXTRACT , 1988, Ancient science of life.

[18]  O. Yoshida,et al.  A newly designed model for infection-induced bladder stone formation in the rat. , 1984, The Journal of urology.

[19]  A. Nadkarni,et al.  Nadkarni's Indian Materia Medica. , 1954 .