Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

[1]  A. Cowman,et al.  Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[2]  W. Milhous,et al.  Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[3]  C. Higgins.  Protein joins transport family , 1989, Nature.

[4]  C. Higgins.  Export-import family expands , 1989, Nature.

[5]  A. Cowman,et al.  Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum , 1989, Cell.

[6]  C. Wilson,et al.  Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. , 1989, Science.

[7]  T. Wellems,et al.  Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[8]  A. Cowman,et al.  Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[9]  W. Milhous,et al.  Plasmodium falciparum: induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro. , 1988, Experimental parasitology.

[10]  I. Gluzman,et al.  Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. , 1987, Science.

[11]  P. Schlesinger,et al.  Acid-vesicle function, intracellular pathogens, and the action of chloroquine against Plasmodium falciparum. , 1987, The New England journal of medicine.

[12]  T. Burkot,et al.  Genetic analysis of the human malaria parasite Plasmodium falciparum. , 1987, Science.

[13]  T. McCutchan,et al.  A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum , 1987, Cell.

[14]  W. Milhous,et al.  Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. , 1987, Science.

[15]  D. Housman,et al.  Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins , 1986, Cell.

[16]  Y. D. Sharma,et al.  Histidine-rich domain of the knob protein of the human malaria parasite Plasmodium falciparum. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[17]  I. Gluzman,et al.  Antimalarials increase vesicle pH in Plasmodium falciparum , 1985, The Journal of cell biology.

[18]  H. Ginsburg,et al.  Susceptibility of human malaria parasites to chloroquine is pH dependent. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Ravetch,et al.  Isolation of the gene for a glycophorin-binding protein implicated in erythrocyte invasion by a malaria parasite. , 1985, Science.

[20]  H. Ginsburg,et al.  Identification of the acidic compartment of Plasmodium falciparum‐infected human erythrocytes as the target of the antimalarial drug chloroquine. , 1984, The EMBO journal.

[21]  W. Trager,et al.  Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum. , 1983, The American journal of tropical medicine and hygiene.

[22]  J. Vanderberg,et al.  Complete in vitro maturation of Plasmodium falciparum gametocytes , 1981, Nature.

[23]  V. Rosário.  Cloning of naturally occurring mixed infections of malaria parasites. , 1981, Science.

[24]  J. Weber.  Analysis of sequences from the extremely A + T-rich genome of Plasmodium falciparum. , 1987, Gene.

[25]  J. Ravetch,et al.  A chromosomal rearrangement in a P. falciparum histidine-rich protein gene is associated with the knobless phenotype , 1986, Nature.

[26]  J. Verhave,et al.  The production of mature gametocytes of Plasmodium falciparum in continuous cultures of different isolates infective to mosquitoes. , 1982, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[27]  W. Trager,et al.  Isolation of stages of the human parasite Plasmodium falciparum from culture and from animal blood. , 1979, Bulletin of the World Health Organization.