Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis.

[1]  R. Holmdahl,et al.  Role of the galactosyl moiety of collagen glycopeptides for T-cell stimulation in a model for rheumatoid arthritis. , 2003, Bioorganic & Medicinal Chemistry.

[2]  J. Smolen,et al.  Therapeutic strategies for rheumatoid arthritis , 2003, Nature Reviews Drug Discovery.

[3]  R. Holmdahl,et al.  Glycopeptide Specificity of Helper T Cells Obtained in Mouse Models for Rheumatoid Arthritis , 2002, Chembiochem : a European journal of chemical biology.

[4]  R. Holmdahl,et al.  Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen‐induced arthritis , 2002, European journal of immunology.

[5]  L. Fugger,et al.  Predominant selection of T cells specific for the glycosylated collagen type II epitope (263–270) in humanized transgenic mice and in rheumatoid arthritis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[6]  C. Beeson,et al.  Binding interactions between peptides and proteins of the class II Major Histocompatibility Complex , 2002, Medicinal research reviews.

[7]  J. Pinkner,et al.  Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli , 2001, Chembiochem : a European journal of chemical biology.

[8]  J. Kihlberg,et al.  An Improved Synthesis of a Galactosylated Hydroxylysine Building Block and its use in Solid-Phase Glycopeptide Synthesis , 2000 .

[9]  J. Kihlberg,et al.  Preparation of a Diglycosylated Hydroxylysine Building Block Used in Solid-Phase Synthesis of a Glycopeptide from Type II Collagen. , 1999, The Journal of organic chemistry.

[10]  R. Holmdahl,et al.  Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen‐induced arthritis , 1998, European journal of immunology.

[11]  R. Holmdahl,et al.  T Cells Recognize a Glycopeptide Derived from Type II Collagen in a Model for Rheumatoid Arthritis , 1998 .

[12]  L. Fugger,et al.  The structural basis of MHC control of collagen‐induced arthritis; binding of the immunodominant type II collagen 256 – 270 glycopeptide to H‐2Aq and H‐2Ap molecules , 1998, European journal of immunology.

[13]  D. Brand,et al.  Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis. , 1996, Cellular immunology.

[14]  R. Holmdahl,et al.  Antigen processing and presentation of a naturally glycosylated protein elicits major histocompatibility complex class II‐restricted, carbohydrate‐specific T cells , 1996, European journal of immunology.

[15]  Garland R. Marshall,et al.  VALIDATE: A New Method for the Receptor-Based Prediction of Binding Affinities of Novel Ligands , 1996 .

[16]  Lars Fugger,et al.  Quantitative Analysis of Peptides from Myelin Basic Protein Binding to the MHC Class II Protein, I-Au, Which Confers Susceptibility to Experimental Allergic Encephalomyelitis , 1996, Molecular medicine.

[17]  R. Holmdahl,et al.  T cell recognition of carbohydrates on type II collagen , 1994, The Journal of experimental medicine.

[18]  Don C. Wiley,et al.  Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide , 1994, Nature.

[19]  J. Rothbard,et al.  Exploration of requirements for peptide binding to HLA DRB1*0101 and DRB1*0401. , 1994, Journal of immunology.

[20]  A. Kang,et al.  Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice. , 1994, Journal of immunology.

[21]  R. Holmdahl,et al.  Identification of an immunodominant type‐II collagen peptide recognized by T cells in H‐2q mice: self tolerance at the level of determinant selection , 1992, European journal of immunology.

[22]  G. Chang,et al.  Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics , 1990 .

[23]  R. Holmdahl,et al.  Localization of a critical restriction site on the I-A beta chain that determines susceptibility to collagen-induced arthritis in mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[24]  R. Holmdahl,et al.  Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis. , 1988, Immunology.

[25]  M. Liang,et al.  The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. , 1988, Arthritis and rheumatism.

[26]  G. Charriere,et al.  Antibodies to types I, II, IX, and XI collagen in the serum of patients with rheumatic diseases. , 1988, Arthritis and rheumatism.

[27]  H. Luthra,et al.  Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates , 1981, The Journal of experimental medicine.

[28]  M. Dallman,et al.  Immunisation against heterologous type II collagen induces arthritis in mice , 1980, Nature.

[29]  A. Kang,et al.  Autoimmunity to type II collagen an experimental model of arthritis , 1977, The Journal of experimental medicine.

[30]  Kendall A. Smith,et al.  Long term culture of tumour-specific cytotoxic T cells , 1977, Nature.

[31]  G. Kolarz,et al.  Demonstration of antibodies to collagen and of collagen-anticollagen immune complexes in rheumatoid arthritis synovial fluids , 1976, Annals of the rheumatic diseases.

[32]  P. Stastny Mixed lymphocyte cultures in rheumatoid arthritis. , 1976, The Journal of clinical investigation.

[33]  G. Astorga,et al.  Altered reactivity in mixed lymphocyte culture of lymphocytes from patients with rheumatoid arthritis. , 1969, Arthritis and rheumatism.

[34]  R. Spiro The structure of the disaccharide unit of the renal glomerular basement membrane. , 1967, The Journal of biological chemistry.

[35]  M. Feldmann,et al.  Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis. , 1989, Proceedings of the National Academy of Sciences of the United States of America.