Functional coupling of transcription and splicing.

[1]  K. Lukyanov,et al.  Analysis of alternative splicing of cassette exons at single-cell level using two fluorescent proteins , 2012, Nucleic acids research.

[2]  M. Blanchette,et al.  TCERG1 Regulates Alternative Splicing of the Bcl-x Gene by Modulating the Rate of RNA Polymerase II Transcription , 2011, Molecular and Cellular Biology.

[3]  L. Feuk,et al.  Total RNA sequencing reveals nascent transcription and widespread co-transcriptional splicing in the human brain , 2011, Nature Structural &Molecular Biology.

[4]  B. Séraphin,et al.  Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain. , 2011, RNA.

[5]  Noemí Sánchez-Hernández,et al.  Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells , 2011, Genetics research international.

[6]  Sanjay Tyagi,et al.  Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing , 2011, Cell.

[7]  Amit P. Sheth,et al.  RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3′ End Processing , 2011, Science.

[8]  R. Sandberg,et al.  CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing , 2011, Nature.

[9]  A. Ö. Farrants,et al.  SWI/SNF regulates the alternative processing of a specific subset of pre-mRNAs in Drosophila melanogaster , 2011, BMC Molecular Biology.

[10]  M. Carmo-Fonseca,et al.  Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3′ end of human genes , 2011, Nature Structural &Molecular Biology.

[11]  Auinash Kalsotra,et al.  Functional consequences of developmentally regulated alternative splicing , 2011, Nature Reviews Genetics.

[12]  Stuart Aitken,et al.  Modelling Reveals Kinetic Advantages of Co-Transcriptional Splicing , 2011, PLoS Comput. Biol..

[13]  Ian M. Carr,et al.  The proteomes of transcription factories containing RNA polymerases I, II or III , 2011, Nature Methods.

[14]  Maria Carmo-Fonseca,et al.  Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36 , 2011, Nature Structural &Molecular Biology.

[15]  J. Valcárcel,et al.  The Ewing sarcoma protein regulates DNA damage-induced alternative splicing. , 2011, Molecular cell.

[16]  Hyunmin Kim,et al.  Pre-mRNA splicing is a determinant of histone H3K36 methylation , 2011, Proceedings of the National Academy of Sciences.

[17]  Nicole I Bieberstein,et al.  Pause locally, splice globally. , 2011, Trends in cell biology.

[18]  D. Auboeuf,et al.  Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation , 2011, The Journal of cell biology.

[19]  M. Levine.  Paused RNA Polymerase II as a Developmental Checkpoint , 2011, Cell.

[20]  Bin Wu,et al.  Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene , 2011, Science.

[21]  Luis Alejandro Rojas,et al.  The C-Terminal Domain of RNA Polymerase II Is Modified by Site-Specific Methylation , 2011, Science.

[22]  M. Blanchette,et al.  Evolution of a tissue-specific splicing network. , 2011, Genes & development.

[23]  M. Moore,et al.  Ordered and Dynamic Assembly of Single Spliceosomes , 2011, Science.

[24]  Arun K. Ramani,et al.  Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. , 2011, Genome research.

[25]  C. Muchardt,et al.  Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons , 2011, Nature Structural &Molecular Biology.

[26]  Jaroslav Icha,et al.  Histone Deacetylase Activity Modulates Alternative Splicing , 2011, PloS one.

[27]  X. Darzacq,et al.  The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing , 2011, PLoS biology.

[28]  Ross D. Alexander,et al.  Splicing-Dependent RNA Polymerase Pausing in Yeast , 2010, Molecular cell.

[29]  S. Preibisch,et al.  Global analysis of nascent RNA reveals transcriptional pausing in terminal exons. , 2010, Molecular cell.

[30]  Bin Xie,et al.  Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation , 2010, Cell.

[31]  L. Corcos,et al.  Cotranscriptional exon skipping in the genotoxic stress response , 2010, Nature Structural &Molecular Biology.

[32]  Keith R. Yamamoto,et al.  Reciprocal intronic and exonic histone modification regions in humans , 2010, Nature Structural &Molecular Biology.

[33]  R. Reed,et al.  A role for TREX components in the release of spliced mRNA from nuclear speckle domains. , 2010, Nature communications.

[34]  J. Lis,et al.  CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. , 2010, Genes & development.

[35]  I. Poser,et al.  The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells , 2010, The Journal of cell biology.

[36]  Edwin Smith,et al.  The Language of Histone Crosstalk , 2010, Cell.

[37]  A. Kornblihtt,et al.  The carboxy terminal domain of RNA polymerase II and alternative splicing. , 2010, Trends in biochemical sciences.

[38]  Peter Saffrey,et al.  Complex Exon-Intron Marking by Histone Modifications Is Not Determined Solely by Nucleosome Distribution , 2010, PloS one.

[39]  Pamela A. Silver,et al.  An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis , 2010, Cell.

[40]  D. Licatalosi,et al.  Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls , 2010, Science.

[41]  Yong Yu,et al.  A model in vitro system for co-transcriptional splicing , 2010, Nucleic acids research.

[42]  Brendan J. Frey,et al.  Deciphering the splicing code , 2010, Nature.

[43]  Xin Li,et al.  Chemical-genomic dissection of the CTD code , 2010, Nature Structural &Molecular Biology.

[44]  Noemí Sánchez-Hernández,et al.  Differential Effects of Sumoylation on Transcription and Alternative Splicing by Transcription Elongation Regulator 1 (TCERG1)* , 2010, The Journal of Biological Chemistry.

[45]  Tina Lenasi,et al.  P-TEFb stimulates transcription elongation and pre-mRNA splicing through multilateral mechanisms , 2010, RNA biology.

[46]  B. Blencowe,et al.  Regulation of Alternative Splicing by Histone Modifications , 2010, Science.

[47]  K. Adelman,et al.  RNA polymerase II stalling mediates cytokine gene expression , 2010, Cell cycle.

[48]  D. Fargo,et al.  Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila , 2010, Science.

[49]  Peter R Cook,et al.  A model for all genomes: the role of transcription factories. , 2010, Journal of molecular biology.

[50]  Sarath Chandra Janga,et al.  Dissecting the expression dynamics of RNA-binding proteins in posttranscriptional regulatory networks , 2009, Proceedings of the National Academy of Sciences.

[51]  Bing Ren,et al.  Discovery and Annotation of Functional Chromatin Signatures in the Human Genome , 2009, PLoS Comput. Biol..

[52]  S. Nechaev,et al.  Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling , 2009, Proceedings of the National Academy of Sciences.

[53]  D. Bentley,et al.  "Cotranscriptionality": the transcription elongation complex as a nexus for nuclear transactions. , 2009, Molecular cell.

[54]  Manuel de la Mata,et al.  DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation , 2009, Cell.

[55]  Noah Spies,et al.  Biased chromatin signatures around polyadenylation sites and exons. , 2009, Molecular cell.

[56]  Jan Komorowski,et al.  Nucleosomes are well positioned in exons and carry characteristic histone modifications. , 2009, Genome research.

[57]  D. Black,et al.  Co-transcriptional splicing of constitutive and alternative exons. , 2009, RNA.

[58]  Tracy L. Johnson,et al.  Acetylation by the Transcriptional Coactivator Gcn5 Plays a Novel Role in Co-Transcriptional Spliceosome Assembly , 2009, PLoS genetics.

[59]  G. Ast,et al.  Chromatin organization marks exon-intron structure , 2009, Nature Structural &Molecular Biology.

[60]  Christoforos Nikolaou,et al.  Nucleosome positioning as a determinant of exon recognition , 2009, Nature Structural &Molecular Biology.

[61]  R. Padgett,et al.  Rates of in situ transcription and splicing in large human genes , 2009, Nature Structural &Molecular Biology.

[62]  Carlos Bustamante,et al.  Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II , 2009, Science.

[63]  Jiahai Zhang,et al.  Structure and Function of the Two Tandem WW Domains of the Pre-mRNA Splicing Factor FBP21 (Formin-binding Protein 21)* , 2009, The Journal of Biological Chemistry.

[64]  Manuel de la Mata,et al.  Control of alternative splicing through siRNA-mediated transcriptional gene silencing , 2009, Nature Structural &Molecular Biology.

[65]  Su Guo,et al.  7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development , 2009, Proceedings of the National Academy of Sciences.

[66]  N. Visa,et al.  SWI/SNF Associates with Nascent Pre-mRNPs and Regulates Alternative Pre-mRNA Processing , 2009, PLoS genetics.

[67]  D. Spector,et al.  Nuclear neighborhoods and gene expression. , 2009, Current opinion in genetics & development.

[68]  M. Garcia-Blanco,et al.  The Carboxyl-terminal Domain of RNA Polymerase II Is Not Sufficient to Enhance the Efficiency of Pre-mRNA Capping or Splicing in the Context of a Different Polymerase* , 2009, Journal of Biological Chemistry.

[69]  M. Alló,et al.  Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing , 2009, Proceedings of the National Academy of Sciences.

[70]  R. Loomis,et al.  Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation. , 2009, Molecular cell.

[71]  C. Will,et al.  The Spliceosome: Design Principles of a Dynamic RNP Machine , 2009, Cell.

[72]  Melissa J. Moore,et al.  Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation , 2009, Cell.

[73]  B. Hartmann,et al.  Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells , 2009, Genome Biology.

[74]  J. Castle,et al.  A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart , 2008, Proceedings of the National Academy of Sciences.

[75]  J. Ahringer,et al.  Differential chromatin marking of introns and expressed exons by H3K36me3 , 2008, Nature Genetics.

[76]  B. Frey,et al.  Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing , 2008, Nature Genetics.

[77]  Z. Klase,et al.  Bromodomain Protein Brd4 Regulates Human Immunodeficiency Virus Transcription through Phosphorylation of CDK9 at Threonine 29 , 2008, Journal of Virology.

[78]  J. Valcárcel,et al.  RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition. , 2008, Molecular cell.

[79]  Eric T. Wang,et al.  Alternative Isoform Regulation in Human Tissue Transcriptomes , 2008, Nature.

[80]  Xiang-Dong Fu,et al.  The splicing factor SC35 has an active role in transcriptional elongation , 2008, Nature Structural &Molecular Biology.

[81]  Leping Li,et al.  NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly. , 2008, Genes & development.

[82]  S. Nechaev,et al.  Promoter-proximal Pol II: When stalling speeds things up , 2008, Cell cycle.

[83]  Shona Murphy,et al.  Cracking the RNA polymerase II CTD code. , 2008, Trends in genetics : TIG.

[84]  B. Blencowe,et al.  Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay , 2008, Molecular and Cellular Biology.

[85]  C. Muchardt,et al.  Splicing, transcription, and chromatin: a ménage à trois. , 2008, Current opinion in genetics & development.

[86]  John T. Lis,et al.  Transcription Regulation Through Promoter-Proximal Pausing of RNA Polymerase II , 2008, Science.

[87]  A. Kornblihtt,et al.  Identification of the Cellular Targets of the Transcription Factor TCERG1 Reveals a Prevalent Role in mRNA Processing* , 2008, Journal of Biological Chemistry.

[88]  Manolis Kellis,et al.  RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo , 2007, Nature Genetics.

[89]  Ruchir Shah,et al.  RNA polymerase is poised for activation across the genome , 2007, Nature Genetics.

[90]  Paul Tempst,et al.  Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. , 2007, Molecular cell.

[91]  Guey-Shin Wang,et al.  Splicing in disease: disruption of the splicing code and the decoding machinery , 2007, Nature Reviews Genetics.

[92]  J. Ule,et al.  Evolution of Nova-Dependent Splicing Regulation in the Brain , 2007, PLoS genetics.

[93]  E. Seto,et al.  HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention , 2007, Oncogene.

[94]  William Stafford Noble,et al.  Nucleosome positioning signals in genomic DNA. , 2007, Genome research.

[95]  J. Keene.  RNA regulons: coordination of post-transcriptional events , 2007, Nature Reviews Genetics.

[96]  A. Krainer,et al.  SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. , 2007, Molecular cell.

[97]  Yingming Zhao,et al.  Wwp2-Mediated Ubiquitination of the RNA Polymerase II Large Subunit in Mouse Embryonic Pluripotent Stem Cells , 2007, Molecular and Cellular Biology.

[98]  B. A. Ballif,et al.  ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage , 2007, Science.

[99]  T. Kouzarides.  Chromatin Modifications and Their Function , 2007, Cell.

[100]  Bing Li,et al.  The Role of Chromatin during Transcription , 2007, Cell.

[101]  J. Côté,et al.  The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing. , 2007, Molecular cell.

[102]  D. Wassarman,et al.  ATM and ATR Pathways Signal Alternative Splicing of Drosophila TAF1 Pre-mRNA in Response to DNA Damage , 2006, Molecular and Cellular Biology.

[103]  H. Phatnani,et al.  Phosphorylation and functions of the RNA polymerase II CTD. , 2006, Genes & development.

[104]  A. Kornblihtt,et al.  RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20 , 2006, Nature Structural &Molecular Biology.

[105]  Donny D. Licatalosi,et al.  Splicing Regulation in Neurologic Disease , 2006, Neuron.

[106]  L. Cardon,et al.  Replication of twelve association studies for Huntington’s disease residual age of onset in large Venezuelan kindreds , 2006, Journal of Medical Genetics.

[107]  K. Neugebauer,et al.  Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells , 2006, Nature Structural &Molecular Biology.

[108]  Juan Valcárcel,et al.  A simple principle to explain the evolution of pre-mRNA splicing. , 2006, Genes & development.

[109]  M. Garcia-Blanco,et al.  Human Transcription Elongation Factor CA150 Localizes to Splicing Factor-Rich Nuclear Speckles and Assembles Transcription and Splicing Components into Complexes through Its Amino and Carboxyl Regions , 2006, Molecular and Cellular Biology.

[110]  Henning Urlaub,et al.  Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions , 2006, Molecular and Cellular Biology.

[111]  K. J. Hertel,et al.  Linking Splicing to Pol II Transcription Stabilizes Pre-mRNAs and Influences Splicing Patterns , 2006, PLoS biology.

[112]  R. Reed,et al.  Functional coupling of RNAP II transcription to spliceosome assembly. , 2006, Genes & development.

[113]  Christian Néri,et al.  CA150 Expression Delays Striatal Cell Death in Overexpression and Knock-In Conditions for Mutant Huntingtin Neurotoxicity , 2006, The Journal of Neuroscience.

[114]  A. Pombo,et al.  Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations , 2006, PLoS biology.

[115]  Andrew J Link,et al.  The Splicing Factor PSF is Part of a Large Complex That Assembles in the Absence of pre-mRNA and Contains All 5 snRNPs , 2006, RNA biology.

[116]  Juan Valcárcel,et al.  The expanding transcriptome: the genome as the ‘Book of Sand’ , 2006, The EMBO journal.

[117]  M. Macias,et al.  The Structure of Prp40 FF1 Domain and Its Interaction with the crn-TPR1 Motif of Clf1 Gives a New Insight into the Binding Mode of FF Domains* , 2006, Journal of Biological Chemistry.

[118]  M. Garcia-Blanco,et al.  In vitro coupled transcription splicing. , 2005, Methods.

[119]  A. Lamond,et al.  P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner. , 2005, Molecular biology of the cell.

[120]  Robert Castelo,et al.  Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition. , 2005, Molecular cell.

[121]  Maho Takahashi,et al.  Coactivator-associated Arginine Methyltransferase 1, CARM1, Affects Pre-mRNA Splicing in an Isoform-specific Manner*♦ , 2005, Journal of Biological Chemistry.

[122]  John A. Calarco,et al.  Role for PSF in Mediating Transcriptional Activator-Dependent Stimulation of Pre-mRNA Processing In Vivo , 2005, Molecular and Cellular Biology.

[123]  S. Lacadie,et al.  Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast. , 2005, Molecular cell.

[124]  K. Neugebauer,et al.  Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex. , 2005, Molecular cell.

[125]  Loni Pickle,et al.  A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. , 2005, Genes & development.

[126]  T. Pawson,et al.  FF Domains of CA150 Bind Transcription and Splicing Factors through Multiple Weak Interactions , 2004, Molecular and Cellular Biology.

[127]  Danny Reinberg,et al.  Elongation by RNA polymerase II: the short and long of it. , 2004, Genes & development.

[128]  Kai Lin,et al.  The WW Domain-Containing Proteins Interact with the Early Spliceosome and Participate in Pre-mRNA Splicing In Vivo , 2004, Molecular and Cellular Biology.

[129]  A. Kornblihtt,et al.  Multiple links between transcription and splicing. , 2004, RNA.

[130]  S. Edwards,et al.  Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications , 2004, Cellular and Molecular Life Sciences CMLS.

[131]  M. Garcia-Blanco,et al.  Alternative splicing in disease and therapy , 2004, Nature Biotechnology.

[132]  S. Kameoka,et al.  p54nrb associates with the 5′ splice site within large transcription/splicing complexes , 2004, The EMBO journal.

[133]  B. Blencowe,et al.  Analysis of the requirement for RNA polymerase II CTD heptapeptide repeats in pre-mRNA splicing and 3'-end cleavage. , 2004, RNA.

[134]  B. Blencowe,et al.  In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei. , 2004, RNA.

[135]  J. Buschdorf,et al.  A WW domain binding region in methyl-CpG-binding protein MeCP2: impact on Rett syndrome , 2004, Journal of Molecular Medicine.

[136]  S. Buratowski,et al.  The CTD code , 2003, Nature Structural Biology.

[137]  M. Vigneron,et al.  A 10 residue motif at the C‐terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing , 2003, The EMBO journal.

[138]  D. Lockshon,et al.  Cotranscriptional Recruitment of the U1 snRNP to Intron-Containing Genes in Yeast , 2003, Molecular and Cellular Biology.

[139]  A. Kornblihtt,et al.  A slow RNA polymerase II affects alternative splicing in vivo. , 2003, Molecular cell.

[140]  A. Kornblihtt,et al.  Transcriptional Activators Differ in Their Abilities to Control Alternative Splicing* , 2002, The Journal of Biological Chemistry.

[141]  M. Bycroft,et al.  The structure of an FF domain from human HYPA/FBP11. , 2002, Journal of molecular biology.

[142]  Henning Urlaub,et al.  Small Nuclear Ribonucleoprotein Remodeling During Catalytic Activation of the Spliceosome , 2002, Science.

[143]  I. Pérez,et al.  PSF and p54nrb bind a conserved stem in U5 snRNA. , 2002, RNA.

[144]  B. Blencowe,et al.  Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD. , 2002, RNA.

[145]  D. Price,et al.  Functional coupling of capping and transcription of mRNA. , 2002, Molecular cell.

[146]  M. Mann,et al.  Large-scale Proteomic Analysis of the Human Spliceosome References , 2006 .

[147]  Bosiljka Tasic,et al.  Alternative pre-mRNA splicing and proteome expansion in metazoans , 2002, Nature.

[148]  Andrew J. Bannister,et al.  Histone Methylation Dynamic or Static? , 2002, Cell.

[149]  A. Kornblihtt,et al.  Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[150]  S. Yamashita,et al.  Aurora-B associated protein phosphatases as negative regulators of kinase activation , 2002, Oncogene.

[151]  T. Maniatis,et al.  An extensive network of coupling among gene expression machines , 2002, Nature.

[152]  A. Kornblihtt,et al.  Alternative splicing: multiple control mechanisms and involvement in human disease. , 2002, Trends in genetics : TIG.

[153]  Erich A Nigg,et al.  Aurora‐B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation , 2002, Genes to cells : devoted to molecular & cellular mechanisms.

[154]  Qiang Zhou,et al.  Stimulatory effect of splicing factors on transcriptional elongation , 2001, Nature.

[155]  M. Garcia-Blanco,et al.  The Transcription Elongation Factor CA150 Interacts with RNA Polymerase II and the Pre-mRNA Splicing Factor SF1 , 2001, Molecular and Cellular Biology.

[156]  M. Garcia-Blanco,et al.  Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. , 2001, Gene.

[157]  A. Kornblihtt,et al.  Antagonistic effects of T‐Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing , 2001, The EMBO journal.

[158]  B. Chait,et al.  Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo , 2001, Molecular and Cellular Biology.

[159]  C. Will,et al.  Spliceosomal UsnRNP biogenesis, structure and function. , 2001, Current opinion in cell biology.

[160]  M. Hayden,et al.  The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[161]  A. Greenleaf,et al.  The Splicing Factor, Prp40, Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II* , 2000, The Journal of Biological Chemistry.

[162]  S. Berget,et al.  Participation of the C-Terminal Domain of RNA Polymerase II in Exon Definition during Pre-mRNA Splicing , 2000, Molecular and Cellular Biology.

[163]  D. Bentley,et al.  Dynamic association of capping enzymes with transcribing RNA polymerase II. , 2000, Genes & development.

[164]  E. Cho,et al.  Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. , 2000, Genes & development.

[165]  Russ P. Carstens,et al.  An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein , 2000, Molecular and Cellular Biology.

[166]  Danny Reinberg,et al.  RNA polymerase II elongation through chromatin , 2000, Nature.

[167]  M. MacDonald,et al.  Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis. , 2000, Human molecular genetics.

[168]  J. Mcneil,et al.  Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain. , 2000 .

[169]  M. Garcia-Blanco,et al.  Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[170]  H. Phatnani,et al.  Phospho-Carboxyl-Terminal Domain Binding and the Role of a Prolyl Isomerase in Pre-mRNA 3′-End Formation* , 1999, The Journal of Biological Chemistry.

[171]  A. Kornblihtt,et al.  Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. , 1999, Molecular cell.

[172]  M. Bedford,et al.  The FF domain: a novel motif that often accompanies WW domains. , 1999, Trends in biochemical sciences.

[173]  T. Misteli,et al.  RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. , 1999, Molecular cell.

[174]  J. Manley,et al.  Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. , 1999, Genes & development.

[175]  G. C. Roberts,et al.  Co-transcriptional commitment to alternative splice site selection. , 1998, Nucleic acids research.

[176]  P. Leder,et al.  WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[177]  Juri Rappsilber,et al.  Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex , 1998, Nature Genetics.

[178]  M. MacDonald,et al.  Huntingtin interacts with a family of WW domain proteins. , 1998, Human molecular genetics.

[179]  M. Rosbash,et al.  A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. , 1998, Genes & development.

[180]  R. Young,et al.  CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription , 1997, Molecular and cellular biology.

[181]  I. Stagljar,et al.  A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II. , 1997, Nucleic acids research.

[182]  M. Rosbash,et al.  The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC , 1997, Cell.

[183]  M. Rosbash,et al.  Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals , 1997, Cell.

[184]  M. Wickens,et al.  The C-terminal domain of RNA polymerase II couples mRNA processing to transcription , 1997, Nature.

[185]  L. Du,et al.  A Functional Interaction between the Carboxy-Terminal Domain of RNA Polymerase II and Pre-mRNA Splicing , 1997, The Journal of cell biology.

[186]  A. Yuryev,et al.  The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[187]  P. Leder,et al.  Formin binding proteins bear WWP/WW domains that bind proline‐rich peptides and functionally resemble SH3 domains. , 1996, The EMBO journal.

[188]  H. Kao,et al.  Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle , 1996, Molecular and Cellular Biology.

[189]  P. Sharp,et al.  Dynamic association of proteins with the pre-mRNA branch region. , 1994, Genes & development.

[190]  L. Wieslander,et al.  Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription , 1994, Cell.

[191]  Tom Maniatis,et al.  Specific interactions between proteins implicated in splice site selection and regulated alternative splicing , 1993, Cell.

[192]  J. Wang,et al.  Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[193]  A. Krainer,et al.  Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6. , 1993, Nucleic acids research.

[194]  W. G. Kelly,et al.  RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc. , 1993, The Journal of biological chemistry.

[195]  M. Groudine,et al.  The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region. , 1992, Genes & development.

[196]  G. Adami,et al.  DNA template effect on RNA splicing: two copies of the same gene in the same nucleus are processed differently. , 1991, The EMBO journal.

[197]  J. Lis,et al.  RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene , 1991, Molecular and cellular biology.

[198]  D. Luse,et al.  Transcription on nucleosomal templates by RNA polymerase II in vitro: inhibition of elongation with enhancement of sequence-specific pausing. , 1991, Genes & development.

[199]  E N Trifonov,et al.  Splice junctions follow a 205-base ladder. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[200]  J Zhang,et al.  Identification of phosphorylation sites in the repetitive carboxyl-terminal domain of the mouse RNA polymerase II largest subunit. , 1991, The Journal of biological chemistry.

[201]  I. Graham,et al.  Effects of RNA secondary structure on alternative splicing of Pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase? , 1988, Cell.

[202]  Y. Osheim,et al.  Visualization of Drosophila melanogaster chorion genes undergoing amplification , 1988, Molecular and cellular biology.

[203]  Y. Osheim,et al.  Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. , 1988, Genes & development.

[204]  P. Luciw,et al.  Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product , 1987, Nature.

[205]  Mark Groudine,et al.  A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells , 1986, Nature.

[206]  A. Greenleaf,et al.  Properties of mutationally altered RNA polymerases II of Drosophila. , 1982, The Journal of biological chemistry.

[207]  D. Larson,et al.  Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. , 2010, Cold Spring Harbor Symposia on Quantitative Biology.

[208]  D. Bentley,et al.  RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes , 2008, Nature Structural &Molecular Biology.

[209]  Xiang-Dong Fu,et al.  SR proteins and related factors in alternative splicing. , 2007, Advances in experimental medicine and biology.

[210]  Giacomo Cavalli,et al.  Chromosome kissing. , 2007, Current opinion in genetics & development.

[211]  M. Moore,et al.  Spliceosome assembly and composition. , 2007, Advances in experimental medicine and biology.

[212]  J. Ule,et al.  Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain. , 2007, Advances in experimental medicine and biology.

[213]  M. Yaniv,et al.  The human SWI/SNF subunit Brm is a regulator of alternative splicing , 2006, Nature Structural &Molecular Biology.

[214]  A. Krämer,et al.  The structure and function of proteins involved in mammalian pre-mRNA splicing. , 1996, Annual review of biochemistry.