Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase.
暂无分享,去创建一个
Pál Pacher | B. Cravatt | Z. Ungvari | A. Csiszar | L. Liaudet | P. Pacher | S. Batkai | P. Mukhopadhyay | M. Rajesh | Benjamin F Cravatt | G. Haskó | Mohanraj Rajesh | Partha Mukhopadhyay | Sándor Bátkai | György Haskó | Lucas Liaudet | Anna Csiszár | Zoltan Ungvári | Mohamraj Rajesh | Gorgy Hasko
[1] Z. Ungvari,et al. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. , 2007, The American journal of pathology.
[2] A. Sanyal,et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis , 2001, Nature Medicine.
[3] S. Gaetani,et al. Oleoylethanolamide, an endogenous PPAR-α agonist, lowers body weight and hyperlipidemia in obese rats , 2005, Neuropharmacology.
[4] R. Schwabe,et al. Fatty Acid Amide Hydrolase Determines Anandamide-induced Cell Death in the Liver* , 2006, Journal of Biological Chemistry.
[5] N. Ueda,et al. Partial Purification and Characterization of the Porcine Brain Enzyme Hydrolyzing and Synthesizing Anandamide (*) , 1995, The Journal of Biological Chemistry.
[6] F. Mach,et al. Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice , 2005, Nature.
[7] D. Kipmen-Korgun,et al. Anandamide initiates Ca2+ signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells , 2003 .
[8] B. Cravatt,et al. The endogenous cannabinoid system and its role in nociceptive behavior. , 2004, Journal of neurobiology.
[9] K. Mackie,et al. Endocannabinoids Acting at Cannabinoid-1 Receptors Regulate Cardiovascular Function in Hypertension , 2004, Circulation.
[10] T. Hintze,et al. NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats. , 2003, American journal of physiology. Heart and circulatory physiology.
[11] R. Watson,et al. Modulation of iNOS activity in age-related cardiac dysfunction. , 2004, Life sciences.
[12] T. Bonner,et al. Structure of a cannabinoid receptor and functional expression of the cloned cDNA , 1990, Nature.
[13] D. Kipmen-Korgun,et al. Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells. , 2003, British journal of pharmacology.
[14] Alan Saghatelian,et al. Functional disassociation of the central and peripheral fatty acid amide signaling systems. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[15] C. Ni,et al. ICAM-1 induction by TNFalpha and IL-6 is mediated by distinct pathways via Rac in endothelial cells. , 2005, Journal of biomedical science.
[16] B. Cravatt,et al. Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. , 2003, Current opinion in chemical biology.
[17] Z. Vogel,et al. Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production , 2006, Molecular and Cellular Biochemistry.
[18] M. Valenti,et al. The FASEB Journal express article 10.1096/fj.05-4943fje. Published online January 10, 2006. ©2006 FASEB , 2022 .
[19] B. Cravatt,et al. Hemodynamic profile, responsiveness to anandamide, and baroreflex sensitivity of mice lacking fatty acid amide hydrolase. , 2005, American journal of physiology. Heart and circulatory physiology.
[20] H. Pan,et al. Cannabinoid‐2 receptor mediates protection against hepatic ischemia/reperfusion injury , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[21] D. Gibson,et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. , 1992, Science.
[22] Z. Ungvari,et al. Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. , 2007, The American journal of pathology.
[23] J. Groves,et al. Potent Metalloporphyrin Peroxynitrite Decomposition Catalyst Protects Against the Development of Doxorubicin-Induced Cardiac Dysfunction , 2003, Circulation.
[24] M. Valenti,et al. Up‐regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[25] R. Alexander,et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. , 1993, The Journal of clinical investigation.
[26] Arya M. Sharma,et al. Activation of the peripheral endocannabinoid system in human obesity. , 2005, Diabetes.
[27] A. Planas,et al. The FASEB Journal express article 10.1096/fj.02-0795fje. Published online January 2, 2003. Inhibition of tumor angiogenesis by cannabinoids , 2022 .
[28] D. Piomelli,et al. Oleylethanolamide activates Ras-Erk pathway and improves myocardial function in doxorubicin-induced heart failure. , 2006, Endocrinology.
[29] R. Lerner,et al. Chemical characterization of a family of brain lipids that induce sleep. , 1995, Science.
[30] C. Szabó,et al. Nitrosative stress and pharmacological modulation of heart failure. , 2005, Trends in pharmacological sciences.
[31] C. Trautwein,et al. CB1 cannabinoid receptor antagonism: A new strategy for the treatment of liver fibrosis , 2007, Hepatology.
[32] G. Appendino,et al. Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. , 2003, Molecular pharmacology.
[33] D. Lamontagne,et al. The endogenous cardiac cannabinoid system: a new protective mechanism against myocardial ischemia. , 2006, Archives des maladies du coeur et des vaisseaux.
[34] K. Mackie,et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. , 2005, The Journal of clinical investigation.
[35] L. Petrocellis,et al. The endocannabinoid system and its therapeutic exploitation , 2004, Nature Reviews Drug Discovery.
[36] W. Campbell,et al. Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. , 1999, The American journal of physiology.
[37] Ken Mackie,et al. Cannabinoid receptors as therapeutic targets. , 2006, Annual review of pharmacology and toxicology.
[38] P. Pacher,et al. The Endocannabinoid System as an Emerging Target of Pharmacotherapy , 2006, Pharmacological Reviews.
[39] J. Falck,et al. Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. , 2005, American journal of physiology. Heart and circulatory physiology.
[40] L. Liaudet,et al. Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. , 2007, American journal of physiology. Heart and circulatory physiology.
[41] W. Campbell,et al. Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. , 1995, Biochimica et biophysica acta.
[42] B. Cravatt,et al. The endogenous cannabinoid system protects against colonic inflammation. , 2004, The Journal of clinical investigation.
[43] S. Gaetani,et al. Modulation of anxiety through blockade of anandamide hydrolysis , 2003, Nature Medicine.
[44] M. Korabiowska,et al. Inhibition of nuclear factor-κB attenuates atherosclerosis in apoE/LDLR - double knockout mice , 2005 .
[45] C. Szabó,et al. A New, Potent Poly(ADP-ribose) Polymerase Inhibitor Improves Cardiac and Vascular Dysfunction Associated with Advanced Aging , 2004, Journal of Pharmacology and Experimental Therapeutics.
[46] B. Cravatt,et al. Structure and function of fatty acid amide hydrolase. , 2005, Annual review of biochemistry.
[47] M. Korabiowska,et al. Inhibition of nuclear factor-kappaB attenuates artherosclerosis in apoE/LDLR - double knockout mice. , 2005, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
[48] R. Schwabe,et al. Anandamide induces necrosis in primary hepatic stellate cells , 2005, Hepatology.
[49] H. Nishimatsu,et al. Blockade of Endogenous Cytokines Mitigates Neointimal Formation in Obese Zucker Rats , 2005, Circulation.
[50] J. Liao,et al. A functional role of I kappa B-epsilon in endothelial cell activation. , 2000, Journal of immunology.
[51] Z. Ungvari,et al. Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[52] J. Schwartz,et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons , 1994, Nature.
[53] Y. Izumi,et al. Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF‐κB pathway inhibition , 2006, FEBS letters.
[54] A. Makriyannis,et al. Functional CB1 cannabinoid receptors in human vascular endothelial cells. , 2000, The Biochemical journal.
[55] Stephen P. Mayfield,et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides , 1996, Nature.
[56] Z. Ungvari,et al. Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. , 2005, Current vascular pharmacology.
[57] K. Mackie,et al. Identification functional characterization of brainstem cannabinoid CB2 receptors. , 2022 .
[58] D. Deutsch,et al. Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist. , 1993, Biochemical pharmacology.
[59] P. Pacher,et al. Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock‐out mice , 2004, The Journal of physiology.
[60] Pál Pacher,et al. Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure. , 2004, American journal of physiology. Heart and circulatory physiology.
[61] R. Schulz. Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches. , 2007, Annual review of pharmacology and toxicology.
[62] E. Bertoli,et al. Oleoylethanolamide Protects Human Sperm Cells from Oxidation Stress: Studies on Cases of Idiopathic Infertility1 , 2006, Biology of reproduction.
[63] T. Klein. Cannabinoid-based drugs as anti-inflammatory therapeutics , 2005, Nature Reviews Immunology.
[64] L. Mestre,et al. The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection. , 2006, Biochemical pharmacology.
[65] P. Pacher,et al. Cardiovascular pharmacology of cannabinoids. , 2005, Handbook of experimental pharmacology.
[66] F. Lenz,et al. Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. , 2004, Brain research. Molecular brain research.
[67] Z. Ungvari,et al. Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar Function , 2002, Circulation research.
[68] J. Liao,et al. A Functional Role of IκB-ε in Endothelial Cell Activation1 , 2000, The Journal of Immunology.
[69] B. Cravatt,et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry Published, JLR Papers in Press, January 16, 2004. DOI 10.1194/jlr.M300475-JLR200 , 2004, Journal of Lipid Research.
[70] Z. Vogel,et al. Anandamide Protects from Low Serum-induced Apoptosis via Its Degradation to Ethanolamine* , 2007, Journal of Biological Chemistry.
[71] C. Fowler,et al. Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. , 2007, European journal of pharmacology.
[72] L. Petrocellis,et al. Prostaglandin Ethanolamides (Prostamides): In Vitro Pharmacology and Metabolism , 2004, Journal of Pharmacology and Experimental Therapeutics.
[73] B. Cravatt,et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[74] L. Hovgaard,et al. Inhibition of Tumor Necrosis Factor-&agr; Reduces Atherosclerosis in Apolipoprotein E Knockout Mice , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[75] Peter Libby,et al. The immune response in atherosclerosis: a double-edged sword , 2006, Nature Reviews Immunology.
[76] L. Liaudet,et al. Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.