Instability of uncertain large-scale networks

This paper is concerned with instability analysis of uncertain large-scale networks. First, we present an instability counterpart of the small gain-type robust stability condition for uncertain linear systems without network structure. Next, we extend the instability condition to that for a class of uncertain large-scale networks. Every node in the network has certain homogeneous dynamics and uncertain heterogeneous dynamics. Finally, an illustrative example is presented for instability analysis of an uncertain cyclic gene network model.

[1]  Hyungbo Shim,et al.  Consensus of high-order linear systems using dynamic output feedback compensator: Low gain approach , 2009, Autom..

[2]  M. Steinbuch,et al.  A fast algorithm to computer the H ∞ -norm of a transfer function matrix , 1990 .

[3]  C. Desoer,et al.  Feedback Systems: Input-Output Properties , 1975 .

[4]  Domitilla Del Vecchio,et al.  A method for determining the robustness of bio-molecular oscillator models , 2009, BMC Systems Biology.

[5]  J. Doyle,et al.  Robust and optimal control , 1995, Proceedings of 35th IEEE Conference on Decision and Control.

[6]  M. Elowitz,et al.  A synthetic oscillatory network of transcriptional regulators , 2000, Nature.

[7]  Pablo A. Iglesias,et al.  Quantifying robustness of biochemical network models , 2002, BMC Bioinformatics.

[8]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[9]  Ian Postlethwaite,et al.  Multivariable Feedback Control: Analysis and Design , 1996 .

[10]  D. Hinrichsen,et al.  Mathematical Systems Theory I: Modelling, State Space Analysis, Stability and Robustness , 2010 .

[11]  A Frequency-domain Robust Instability Criterion for Time-varying and Non-linear Systems , 1993 .

[12]  Shinji Hara,et al.  Existence criteria of periodic oscillations in cyclic gene regulatory networks , 2011, Autom..

[13]  Ya. Z. Tsypkin,et al.  STABILITY AND ROBUST STABILITY OF UNIFORM SYSTEMS , 1996 .

[14]  J. Collins,et al.  Construction of a genetic toggle switch in Escherichia coli , 2000, Nature.

[15]  G. Zames On the input-output stability of time-varying nonlinear feedback systems Part one: Conditions derived using concepts of loop gain, conicity, and positivity , 1966 .

[16]  Declan G. Bates,et al.  Feedback Control in Systems Biology , 2011 .

[17]  Hideaki Tanaka,et al.  D-stability and robust stability conditions for LTI systems with generalized frequency variables , 2010, 49th IEEE Conference on Decision and Control (CDC).

[18]  Shoichi Takeda,et al.  Instability of feedback systems by orthogonal decomposition of L 2 , 1973 .

[19]  M. Khammash,et al.  Repressilators and promotilators: loop dynamics in synthetic gene networks , 2005, Proceedings of the 2005, American Control Conference, 2005..

[20]  A. Stoorvogel STABILIZING SOLUTIONS OF THE H ALGEBRAIC RICCATI EQUATION , 1996 .

[21]  M. Vidyasagar L//2-INSTABILITY CRITERIA FOR INTERCONNECTED SYSTEMS. , 1977 .

[22]  Jun-ichi Imura,et al.  An instability condition for uncertain systems toward robust bifurcation analysis , 2013, 2013 European Control Conference (ECC).

[23]  Mathukumalli Vidyasagar,et al.  Input-Output Analysis of Large-Scale Interconnected Systems , 1981 .

[24]  Jun-ichi Imura,et al.  Instability criteria for Lur'e systems toward oscillation analysis of uncertain gene networks , 2013, 2013 American Control Conference.

[25]  J. Willems Least squares stationary optimal control and the algebraic Riccati equation , 1971 .

[26]  Shinji Hara,et al.  Robust stability analysis for cyclic gene regulatory networks with uncertainty , 2011, 2011 8th Asian Control Conference (ASCC).