Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

[1]  L. Santana-Cabrera,et al.  Hydrocephalus after decompressive craniectomy for malignant cerebral infarction , 2015, Clinical Neurology and Neurosurgery.

[2]  Ó. González-Pérez,et al.  The role of EGFR and ErbB family related proteins in the oligodendrocyte specification in germinal niches of the adult mammalian brain , 2013, Front. Cell. Neurosci..

[3]  J. Madsen,et al.  VEGF, which is elevated in the CSF of patients with hydrocephalus, causes ventriculomegaly and ependymal changes in rats , 2013, Experimental Neurology.

[4]  O. Abdullah,et al.  Decorin prevents the development of juvenile communicating hydrocephalus. , 2013, Brain : a journal of neurology.

[5]  R. Harris,et al.  Low nitric oxide bioavailability up-regulates renal heparin binding EGF-like growth factor expression , 2013, Kidney international.

[6]  S. Okubo,et al.  Subarachnoid Hemorrhage-Induced Hydrocephalus in Rats , 2013, Stroke.

[7]  Shuji Sato,et al.  A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF , 2012, PloS one.

[8]  Chun-li Zhang,et al.  Role of Krüppel-Like Factor 4 in Neurogenesis and Radial Neuronal Migration in the Developing Cerebral Cortex , 2012, Molecular and Cellular Biology.

[9]  E. Lo,et al.  Neuregulin-1 Effects on Endothelial and Blood–Brain Barrier Permeability After Experimental Injury , 2012, Translational Stroke Research.

[10]  Shenandoah Robinson,et al.  Neonatal posthemorrhagic hydrocephalus from prematurity: pathophysiology and current treatment concepts. , 2012, Journal of neurosurgery. Pediatrics.

[11]  Y. Yung,et al.  Lysophosphatidic Acid Signaling May Initiate Fetal Hydrocephalus , 2011, Science Translational Medicine.

[12]  Sic L. Chan,et al.  Expression of Aquaporin 1 and 4 in a Congenital Hydrocephalus Rat Model , 2011, Neurosurgery.

[13]  Tong Li,et al.  Thrombin induced TGF-β1 pathway: a cause of communicating hydrocephalus post subarachnoid hemorrhage , 2010 .

[14]  A. Laquérriere,et al.  Evidence for tangential migration disturbances in human lissencephaly resulting from a defect in LIS1, DCX and ARX genes , 2010, Acta Neuropathologica.

[15]  K. Yoneda,et al.  HB-EGF-induced VEGF production and eNOS activation depend on both PI3 kinase and MAP kinase in HaCaT cells. , 2009, Journal of dermatological science.

[16]  J. García-Verdugo,et al.  Disruption of the Neurogenic Niche in the Subventricular Zone of Postnatal Hydrocephalic hyh Mice , 2009, Journal of neuropathology and experimental neurology.

[17]  M. Shibuya,et al.  VEGFR-1 Regulates Adult Olfactory Bulb Neurogenesis and Migration of Neural Progenitors in the Rostral Migratory Stream In Vivo , 2009, The Journal of Neuroscience.

[18]  R. Faull,et al.  The cellular composition and morphological organization of the rostral migratory stream in the adult human brain , 2009, Journal of Chemical Neuroanatomy.

[19]  J. Madsen,et al.  VEGF-A is elevated in CSF of pediatric patients undergoing surgery for hydrocephalus , 2009, Cerebrospinal Fluid Research.

[20]  M. Berry,et al.  High CSF transforming growth factor β levels after subarachnoid haemorrhage: association with chronic communicating hydrocephalus , 2008, Journal of Neurology, Neurosurgery, and Psychiatry.

[21]  J. García-Verdugo,et al.  Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. , 2008, Cell stem cell.

[22]  M. Klagsbrun,et al.  Calcification of multipotent prostate tumor endothelium. , 2008, Cancer cell.

[23]  B. Tranmer,et al.  Heparin-binding EGF-like growth factor mediates oxyhemoglobin-induced suppression of voltage-dependent potassium channels in rabbit cerebral artery myocytes. , 2007, American journal of physiology. Heart and circulatory physiology.

[24]  R. Duman,et al.  VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants , 2007, Proceedings of the National Academy of Sciences.

[25]  B. Conklin,et al.  Development of Hydrocephalus in Mice Expressing the Gi-Coupled GPCR Ro1 RASSL Receptor in Astrocytes , 2007, The Journal of Neuroscience.

[26]  G. Meyer Genetic control of neuronal migrations in human cortical development. , 2006, Advances in anatomy, embryology, and cell biology.

[27]  Hideyuki Okano,et al.  New Neurons Follow the Flow of Cerebrospinal Fluid in the Adult Brain , 2006, Science.

[28]  Colin A. Johnson,et al.  The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat , 2006, Nature Genetics.

[29]  George M. Smith,et al.  Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes , 2005, Glia.

[30]  Q. Anjum,et al.  Hydrocephalus in children. , 2005, JPMA. The Journal of the Pakistan Medical Association.

[31]  M. Hori,et al.  Adenovirus-Mediated Gene Transfer of Heparin-Binding Epidermal Growth Factor-Like Growth Factor Enhances Neurogenesis and Angiogenesis After Focal Cerebral Ischemia in Rats , 2005, Stroke.

[32]  J. Yamate,et al.  Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12. , 2004, Brain research. Developmental brain research.

[33]  O. Marín,et al.  Cell migration in the forebrain. , 2003, Annual review of neuroscience.

[34]  L. Niklason,et al.  Possible Role for Vascular Cell Proliferation in Cerebral Vasospasm After Subarachnoid Hemorrhage , 2003, Stroke.

[35]  Arturo Alvarez-Buylla,et al.  EGF Converts Transit-Amplifying Neurogenic Precursors in the Adult Brain into Multipotent Stem Cells , 2002, Neuron.

[36]  E. Jacobs,et al.  Influence of the Embryonic Preplate on the Organization of the Cerebral Cortex: A Targeted Ablation Model , 2002, The Journal of Neuroscience.

[37]  M. Harrigan,et al.  Intraventricular Infusion of Vascular Endothelial Growth Factor Promotes Cerebral Angiogenesis with Minimal Brain Edema , 2002, Neurosurgery.

[38]  L. Lillien,et al.  EGFRs mediate chemotactic migration in the developing telencephalon. , 2001, Development.

[39]  E. Mekada,et al.  A Dual Signaling Cascade That Regulates the Ectodomain Shedding of Heparin-binding Epidermal Growth Factor-like Growth Factor* , 2001, The Journal of Biological Chemistry.

[40]  K. Bland,et al.  Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. , 2000, Molecular endocrinology.

[41]  J. Abraham,et al.  Heparin blockade of thrombin-induced smooth muscle cell migration involves inhibition of epidermal growth factor (EGF) receptor transactivation by heparin-binding EGF-like growth factor. , 2000, Circulation research.

[42]  E. Stopa,et al.  Altered formation and bulk absorption of cerebrospinal fluid in FGF-2-induced hydrocephalus. , 1999, The American journal of physiology.

[43]  E. Haber,et al.  Vascular Endothelial Growth Factor Induces Heparin-binding Epidermal Growth Factor-like Growth Factor in Vascular Endothelial Cells* , 1998, The Journal of Biological Chemistry.

[44]  M. Klagsbrun,et al.  Heparin-binding EGF-like growth factor. , 1997, Biochimica et biophysica acta.

[45]  F. Gage,et al.  Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain , 1997, The Journal of Neuroscience.

[46]  A. Álvarez-Buylla,et al.  Network of tangential pathways for neuronal migration in adult mammalian brain. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[47]  A. Mantovani,et al.  Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. , 1996, Blood.

[48]  D. van der Kooy,et al.  In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[49]  A. Messing,et al.  Overexpression of TGF‐β1 in the Central Nervous System of Transgenic Mice Results in Hydrocephalus , 1995, Journal of neuropathology and experimental neurology.

[50]  A. Yayon,et al.  Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[51]  M. Klagsbrun,et al.  Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[52]  H. Adams,et al.  Factors associated with hydrocephalus after subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study. , 1989, Archives of neurology.

[53]  David P. Todd,et al.  THE DEARBORN OBSERVATORY. , 1880, Science.

[54]  A. Ullrich,et al.  EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF , 1999, Nature.