Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth

[1]  Anupama E. Gururaj,et al.  Novel Mechanisms of Resistance to Endocrine Therapy: Genomic and Nongenomic Considerations , 2006, Clinical Cancer Research.

[2]  A. Bilancio,et al.  Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. , 2005, Cancer research.

[3]  A. Sahin,et al.  Functional implications of altered subcellular localization of PELP1 in breast cancer cells. , 2005, Cancer research.

[4]  C. Roberts,et al.  Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells. , 2005, Cancer research.

[5]  A. Bilancio,et al.  Role of Atypical Protein Kinase C in Estradiol-Triggered G1/S Progression of MCF-7 Cells , 2004, Molecular and Cellular Biology.

[6]  A. Bilancio,et al.  Androgen-stimulated DNA synthesis and cytoskeletal changes in fibroblasts by a nontranscriptional receptor action , 2003, The Journal of cell biology.

[7]  E. Levin Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor. , 2003, Molecular endocrinology.

[8]  S. Hayward,et al.  Role of stroma in carcinogenesis of the prostate. , 2002, Differentiation; research in biological diversity.

[9]  Chi-Wai Wong,et al.  Estrogen receptor-interacting protein that modulates its nongenomic activity-crosstalk with Src/Erk phosphorylation cascade , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[10]  A. Cato,et al.  Rapid Actions of Steroid Receptors in Cellular Signaling Pathways , 2002, Science's STKE.

[11]  D. Márquez,et al.  Epidermal growth factor receptor and tyrosine phosphorylation of estrogen receptor , 2001, Endocrine.

[12]  A. Bilancio,et al.  PI3‐kinase in concert with Src promotes the S‐phase entry of oestradiol‐stimulated MCF‐7 cells , 2001, The EMBO journal.

[13]  B. Katzenellenbogen,et al.  Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors Dissociation from Transcriptional Activity , 2001, Cell.

[14]  A. Bilancio,et al.  Steroid‐induced androgen receptor–oestradiol receptor β–Src complex triggers prostate cancer cell proliferation , 2000, The EMBO journal.

[15]  K. Ley,et al.  Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase , 2000, Nature.

[16]  Donna M. Peehl,et al.  Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor , 2000, Nature Medicine.

[17]  F. Claessens,et al.  Change of Specificity Mutations in Androgen-selective Enhancers , 2000, The Journal of Biological Chemistry.

[18]  M. Sudol,et al.  The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  A. Bilancio,et al.  Non‐transcriptional action of oestradiol and progestin triggers DNA synthesis , 1999, The EMBO journal.

[20]  D. Dorsa,et al.  The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons , 1999, The Journal of Neuroscience.

[21]  C. López-Otín,et al.  Breast and prostate cancer: an analysis of common epidemiological, genetic, and biochemical features. , 1998, Endocrine reviews.

[22]  Wen-rong Gong,et al.  Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross‐talk with estrogen receptor , 1998, The EMBO journal.

[23]  P. Bontempo,et al.  Tyrosine kinase/p21ras/MAP‐kinase pathway activation by estradiol‐receptor complex in MCF‐7 cells. , 1996, The EMBO journal.

[24]  Chawnshang Chang,et al.  Molecular cloning of human and rat complementary DNA encoding androgen receptors. , 1988, Science.

[25]  G. Castoria,et al.  In vitro interaction of estradiol receptor with Ca2+-calmodulin. , 1988, Molecular Endocrinology.

[26]  R. Vessella,et al.  Molecular determinants of resistance to antiandrogen therapy , 2004, Nature Medicine.

[27]  R. McPherson,et al.  Linkage of Rapid Estrogen Action to MAPK Activation by ER-Shc Association and Shc Pathway Activation , 2001 .

[28]  E. Baldi,et al.  Androgen receptor expression in prostate carcinoma cells suppresses alpha6beta4 integrin-mediated invasive phenotype. , 2000, Endocrinology.

[29]  H. Klocker,et al.  Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. , 1994, Cancer research.

[30]  I. M. Neiman,et al.  [Inflammation and cancer]. , 1974, Patologicheskaia fiziologiia i eksperimental'naia terapiia.