Gut microbial GABAergic signaling improves stress-associated innate immunity to respiratory viral infection

[1]  K. Chow,et al.  Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients , 2022, Gut microbes.

[2]  R. Weissleder,et al.  Brain motor and fear circuits regulate leukocytes during acute stress , 2022, Nature.

[3]  M. Rana,et al.  Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis. , 2022, Cell host & microbe.

[4]  B. McDonald,et al.  Long-distance relationships - regulation of systemic host defense against infections by the gut microbiota , 2022, Mucosal Immunology.

[5]  S. Mazmanian,et al.  Gut microbiome-mediated regulation of neuroinflammation. , 2022, Current opinion in immunology.

[6]  J. Lieberman,et al.  Inflammasome activation in infected macrophages drives COVID-19 pathology , 2021, Nature.

[7]  M. Lazar,et al.  Isoform-specific functions of PPARγ in gene regulation and metabolism , 2022, Genes & development.

[8]  Julien Maurizio,et al.  Long-term culture-expanded alveolar macrophages restore their full epigenetic identity after transfer in vivo , 2022, Nature Immunology.

[9]  Xiao-Fan Wang,et al.  Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression , 2022, Nature Cell Biology.

[10]  Jordi Espadaler Mazo,et al.  Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial , 2022, Gut microbes.

[11]  T. Alenghat,et al.  Epigenetic regulation by gut microbiota , 2022, Gut microbes.

[12]  Yanhua Kang,et al.  PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway , 2022, Frontiers in Immunology.

[13]  A. Rothchild,et al.  Alveolar macrophages: novel therapeutic targets for respiratory diseases , 2021, Expert Reviews in Molecular Medicine.

[14]  C. Plass,et al.  Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease , 2021, Nature Communications.

[15]  Keiichiro Suzuki,et al.  B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity , 2021, Nature.

[16]  S. Bhattacharyya,et al.  α-Ketoglutarate Inhibits Thrombosis and Inflammation by Prolyl Hydroxylase-2 Mediated Inactivation of Phospho-Akt , 2021, EBioMedicine.

[17]  B. Lim,et al.  Effects of RGD-grafted phosphatidylserine-containing liposomes on the polarization of macrophages and bone tissue regeneration. , 2021, Biomaterials.

[18]  E. Boerwinkle,et al.  Analysis of COVID-19 Infection and Mortality Among Patients With Psychiatric Disorders, 2020 , 2021, JAMA network open.

[19]  Jianxin Zhao,et al.  Bifidobacteria exhibited stronger ability to utilize fructooligosaccharides, compared with other bacteria in the mouse intestine. , 2021, Journal of the science of food and agriculture.

[20]  Samouil L. Farhi,et al.  GABA-receptive microglia selectively sculpt developing inhibitory circuits , 2021, Cell.

[21]  V. Sexl,et al.  Murine ex vivo Cultured Alveolar Macrophages Provide a Novel Tool to Study Tissue-Resident Macrophage Behavior and Function. , 2021, American journal of respiratory cell and molecular biology.

[22]  K. Moore,et al.  Chronic stress primes innate immune responses in mice and humans , 2021, Cell reports.

[23]  Brittany D. Needham,et al.  Microbiota regulate social behaviour via stress response neurons in the brain , 2021, Nature.

[24]  A. Bhandage,et al.  GABAergic signaling by cells of the immune system: more the rule than the exception , 2021, Cellular and Molecular Life Sciences.

[25]  Xin Zhang,et al.  Mitochondrial metabolism regulates macrophage biology , 2021, The Journal of biological chemistry.

[26]  Weitao Geng,et al.  Metabolism Characteristics of Lactic Acid Bacteria and the Expanding Applications in Food Industry , 2021, Frontiers in Bioengineering and Biotechnology.

[27]  P. He,et al.  GABAergic synapses suppress intestinal innate immunity via insulin signaling in Caenorhabditis elegans , 2021, Proceedings of the National Academy of Sciences.

[28]  Quynh P. Nguyen,et al.  Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection , 2021, Immunity.

[29]  Xun Sun,et al.  Targeted apoptosis of macrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis , 2021, Nature Communications.

[30]  J. Schneider,et al.  Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis , 2021, Nature Communications.

[31]  Gongying Li,et al.  Fecal microbiota transplantation ameliorates gut microbiota imbalance and intestinal barrier damage in rats with stress‐induced depressive‐like behavior , 2021, The European journal of neuroscience.

[32]  D. Goff,et al.  Association of Psychiatric Disorders With Mortality Among Patients With COVID-19. , 2021, JAMA psychiatry.

[33]  Biqing Chen,et al.  Depression and anxiety in patients with active ulcerative colitis: crosstalk of gut microbiota, metabolomics and proteomics , 2021, Gut microbes.

[34]  B. Colsch,et al.  Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system , 2020, Nature Communications.

[35]  M. Wong,et al.  Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders , 2020, Science Advances.

[36]  L. Joosten,et al.  The Intersection of Epigenetics and Metabolism in Trained Immunity. , 2020, Immunity.

[37]  S. R. Datta,et al.  GABA-receptive microglia selectively sculpt developing inhibitory circuits , 2020, Cell.

[38]  N. Volkow,et al.  Increased risk of COVID‐19 infection and mortality in people with mental disorders: analysis from electronic health records in the United States , 2020, World psychiatry : official journal of the World Psychiatric Association.

[39]  S. Farhadian,et al.  Sex differences in immune responses that underlie COVID-19 disease outcomes , 2020, Nature.

[40]  S. Di Giovanni,et al.  Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19 , 2020, Nature Reviews Neurology.

[41]  Li Lin,et al.  Evodiamine has therapeutic efficacy in ulcerative colitis by increasing Lactobacillus acidophilus levels and acetate production. , 2020, Pharmacological research.

[42]  E. Sibille,et al.  Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders , 2020, Molecular Psychiatry.

[43]  Ji Hyeong Baek,et al.  Glutamine Supplementation Prevents Chronic Stress-Induced Mild Cognitive Impairment , 2020, Nutrients.

[44]  Dean P. Jones,et al.  Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury. , 2020, Cell metabolism.

[45]  E. Elinav,et al.  The microbiota programs DNA methylation to control intestinal homeostasis and inflammation , 2020, Nature Microbiology.

[46]  P. Xie,et al.  An integrated meta-analysis of peripheral blood metabolites and biological functions in major depressive disorder , 2020, Molecular Psychiatry.

[47]  M. Mack,et al.  Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection , 2019, Nature Immunology.

[48]  P. Frenette,et al.  The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation. , 2019, Immunity.

[49]  Tomasz P. Wypych,et al.  The influence of the microbiome on respiratory health , 2019, Nature Immunology.

[50]  R. Månsson,et al.  Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity , 2019, The EMBO journal.

[51]  R. Valdés-Mas,et al.  Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice , 2019, Nature Medicine.

[52]  M. Sieweke,et al.  Isolation and Long-term Cultivation of Mouse Alveolar Macrophages. , 2019, Bio-protocol.

[53]  Bo Zhu,et al.  Daphnetin ameliorates experimental colitis by modulating microbiota composition and Treg/Th17 balance , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[54]  Ming D. Li,et al.  Gut Microbiota Changes in Patients with Bipolar Depression , 2019, Advanced science.

[55]  A. Iwasaki,et al.  Ketogenic diet activates protective γδ T cell responses against influenza virus infection , 2019, Science Immunology.

[56]  J. Raes,et al.  The neuroactive potential of the human gut microbiota in quality of life and depression , 2019, Nature Microbiology.

[57]  Mingbang Wang,et al.  Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder , 2019, mSystems.

[58]  M. Ishii,et al.  GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites , 2019, Nature.

[59]  Karsten Zengler,et al.  GABA Modulating Bacteria of the Human Gut Microbiota , 2018, Nature Microbiology.

[60]  Tristan T. Hays,et al.  The Nuclear Receptor PPAR&ggr; Controls Progressive Macrophage Polarization as a Ligand‐Insensitive Epigenomic Ratchet of Transcriptional Memory , 2018, Immunity.

[61]  E. Hsiao,et al.  The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet , 2018, Cell.

[62]  R. Locksley,et al.  Pulmonary neuroendocrine cells amplify allergic asthma responses , 2018, Science.

[63]  Z. Ju,et al.  Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1α/TNFAIP3 Axis. , 2018, Cell reports.

[64]  L. Birnbaumer,et al.  Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response , 2018, Proceedings of the National Academy of Sciences.

[65]  S. Liberles,et al.  Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia , 2018, Nature Medicine.

[66]  Rebecca L. Brown,et al.  The microbiota protects against respiratory infection via GM-CSF signaling , 2017, Nature Communications.

[67]  H. Hammad,et al.  A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes , 2017, Nature Immunology.

[68]  A. Leutz,et al.  SIRT1 regulates macrophage self‐renewal , 2017, The EMBO journal.

[69]  Maxim N. Artyomov,et al.  The microbial metabolite desaminotyrosine protects from influenza through type I interferon , 2017, Science.

[70]  M. Ota,et al.  Possible association of Bifidobacterium and Lactobacillus in the gut microbiota of patients with major depressive disorder. , 2016, Journal of affective disorders.

[71]  N. Hacohen,et al.  Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells , 2016, Science.

[72]  M. Kurrer,et al.  Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages , 2014, Nature Immunology.

[73]  Alex K. Heer,et al.  Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection , 2014, PLoS pathogens.

[74]  F. Ginhoux,et al.  Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. , 2013, Immunity.

[75]  S. Coughlin,et al.  Anxiety and Depression: Linkages with Viral Diseases , 2012, Public Health Reviews.

[76]  John F. Cryan,et al.  Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve , 2011, Proceedings of the National Academy of Sciences.

[77]  M. Sieweke,et al.  MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages , 2009, Science.

[78]  Erik D Herzog,et al.  GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons , 2006, Proceedings of the National Academy of Sciences.

[79]  G. Wilkinson,et al.  Gender differences in depression. Critical review. , 2000, The British journal of psychiatry : the journal of mental science.

[80]  K. Djafarian,et al.  Gut microbiota and depression , 2021 .

[81]  The Lancet Respiratory Medicine Harnessing the microbiome for lung health. , 2019, The Lancet. Respiratory medicine.